Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Mer The Rejuvenating Night Cream Versus Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face And Neck Creme

La Mer The Rejuvenating Night Cream Versus Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face And Neck Creme Detailed comparison of La Mer The Rejuvenating Night Cream versus Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face And Neck Creme.

This source-based comparison does not add ratings or recommend a winner.

La Mer The Rejuvenating Night Cream Versus Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face And Neck Creme Detailed comparison of La Mer The Rejuvenating Night Cream versus Estée Lauder Resilience Multi-Effect Night Tri-Peptide Face And Neck Creme. This anti-aging night moisturizer is formulated around Butyrospermum Parkii Butter and Palmitoyl Tripeptide-1 to soften the look of wrinkles and hydrate skin. This anti-aging night moisturizer is formulated around Acetyl Hexapeptide-8 to soften the look of wrinkles. Water Algae Extract Butyrospermum Parkii Butter Dimethicone Butylene Glycol Caprylic/Capric/Myristic/Stearic Triglyceride Polyglyceryl-3 Methylglucose Distearate Glycerin Silica Coco-Caprylate/Caprate Simmondsia Chinensis Seed Oil Mangifera Indica Seed Butter Polyglyceryl-10 Pentastearate Glyceryl Stearate Behenyl Alcohol PEG-100 Stearate Dimethicone/Vinyl Dimethicone Crosspolymer Sesamum Indicum Seed Oil Medicago Sativa Seed Powder Helianthus Annuus Seedcake Prunus Amygdalus Dulcis Seed Meal Eucalyptus Globulus Leaf Oil Sodium Gluconate Copper Gluconate Calcium Gluconate Magnesium Gluconate Zinc Gluconate Tocopheryl Succinate Niacin Sesamum Indicum Seed Powder Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Acetyl Hexapeptide-8 Sodium Hyaluronate Crithmum Maritimum Extract Laminaria Digitata Extract Faex Extract Crithmum Maritimum Callus Culture Filtrate Bambusa Vulgaris Extract Citrus Aurantifolia Peel Extract Coffea Arabica Seed Extract Pisum Sativum Extract Magnesium Ascorbyl Phosphate Caffeine Tocopherol Tocopheryl Acetate Lecithin Caprylic/Capric Triglyceride Ethylhexylglycerin Potassium Cetyl Phosphate Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer PEG-8 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Sodium Stearoyl Lactylate Glyceryl Polymethacrylate Carbomer Sodium Hydroxide Polysorbate 60 Glucosamine Hcl Sorbitan Isostearate Polysorbate 20 Hydrogenated Vegetable Oil Caprylyl Glycol Hexylene Glycol Alcohol Denat. Parfum Limonene Linalool Hydroxycitronellal Citronellol Geraniol Benzyl Salicylate Benzyl Benzoate BHT Disodium EDTA Phenoxyethanol Chlorphenesin Potassium Sorbate CI 15985 Water, Algae Extract, Butyrospermum Parkii Butter, Dimethicone, Butylene Glycol, Caprylic/Capric/Myristic/Stearic Triglyceride, Polyglyceryl-3 Methylglucose Distearate, Glycerin, Silica, Coco-Caprylate/Caprate, Simmondsia Chinensis Seed Oil, Mangifera Indica Seed Butter, Polyglyceryl-10 Pentastearate, Glyceryl Stearate, Behenyl Alcohol, PEG-100 Stearate, Dimethicone/Vinyl Dimethicone Crosspolymer, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Helianthus Annuus Seedcake, Prunus Amygdalus Dulcis Seed Meal, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Acetyl Hexapeptide-8, Sodium Hyaluronate, Crithmum Maritimum Extract, Laminaria Digitata Extract, Faex Extract, Crithmum Maritimum Callus Culture Filtrate, Bambusa Vulgaris Extract, Citrus Aurantifolia Peel Extract, Coffea Arabica Seed Extract, Pisum Sativum Extract, Magnesium Ascorbyl Phosphate, Caffeine, Tocopherol, Tocopheryl Acetate, Lecithin, Caprylic/Capric Triglyceride, Ethylhexylglycerin, Potassium Cetyl Phosphate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, PEG-8, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Stearoyl Lact These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Algae Extract is a confusing name. This is because algae is an informal term for a group of 30,000 aquatic organisms that can photosynthesize. The term 'algae extract' can refer to any one, or a blend of, the 30,000 types. Algae is rich in antioxidants. Antioxidants help fight free-radicals. Free-radicals are molecules that may damage your skin cells, such as pollution. Algae can also help with soothing and hydrating skin. Many different types of algae have different benefits. BHT is a synthetic antioxidant and preservative. As an antioxidant, it helps your body fight off free-radicals. Free-radicals are molecules that may damage your skin cells. As a preservative, it is used to stabilize products and prevent them from degrading. Specifically, BHT prevents degradation from oxidation. The concerns related to BHT come from oral studies; this ingredient is currently allowed for use by both the FDA and EU. However, it was recently restricted for use in the UK as of April 2024. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounde