Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Mer The Treatment Lotion Versus Paula's Choice 1% Retinol Treatment

La Mer The Treatment Lotion Versus Paula's Choice 1% Retinol Treatment Detailed comparison of La Mer The Treatment Lotion versus Paula's Choice 1% Retinol Treatment US. This hydrating treatment is formulated around Sodium Hyaluronate and Acetyl Hexapeptide-8 t

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La Mer The Treatment Lotion Versus Paula's Choice 1% Retinol Treatment Detailed comparison of La Mer The Treatment Lotion versus Paula's Choice 1% Retinol Treatment US. This hydrating treatment is formulated around Sodium Hyaluronate and Acetyl Hexapeptide-8 to hydrate skin and strengthen the skin barrier. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Algae Extract Glycerin Methyl Gluceth-20 Bis-PEG-18 Methyl Ether Dimethyl Silane Sucrose Faex Extract Sesamum Indicum Seed Oil Medicago Sativa Seed Powder Prunus Amygdalus Dulcis Seed Meal Helianthus Annuus Seedcake Eucalyptus Globulus Leaf Oil Sodium Gluconate Copper Gluconate Calcium Gluconate Magnesium Gluconate Zinc Gluconate Tocopheryl Succinate Niacin Sesamum Indicum Seed Powder Citrus Aurantifolia Peel Extract Laminaria Digitata Extract Laminaria Saccharina Extract Plankton Extract Palmaria Palmata Extract Sodium Hyaluronate Butylene Glycol Caffeine Dipotassium Glycyrrhizate Acetyl Hexapeptide-8 Glycereth-26 Alcaligenes Polysaccharides Trehalose Lactobacillus Ferment Maris Sal Tourmaline Urea Sodium PCA Glycine Soja Protein Glycosaminoglycans Glycine Soja Seed Extract Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Caprylyl Glycol PEG-8 Magnesium Chloride Calcium Chloride Sodium Sulfate Potassium Phosphate Potassium Nitrate Pentylene Glycol Triacetin Lecithin PPG-5-Ceteth-20 Jojoba Wax PEG-120 Esters Polysorbate 20 Polyquaternium-51 Hydroxypropyl Cyclodextrin Alcohol Denat. Parfum Limonene Linalool Hydroxycitronellal Citronellol Geraniol BHT Disodium EDTA Potassium Sorbate Chlorphenesin Sorbic Acid Phenoxyethanol Water, Algae Extract, Glycerin, Methyl Gluceth-20, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sucrose, Faex Extract, Sesamum Indicum Seed Oil, Medicago Sativa Seed Powder, Prunus Amygdalus Dulcis Seed Meal, Helianthus Annuus Seedcake, Eucalyptus Globulus Leaf Oil, Sodium Gluconate, Copper Gluconate, Calcium Gluconate, Magnesium Gluconate, Zinc Gluconate, Tocopheryl Succinate, Niacin, Sesamum Indicum Seed Powder, Citrus Aurantifolia Peel Extract, Laminaria Digitata Extract, Laminaria Saccharina Extract, Plankton Extract, Palmaria Palmata Extract, Sodium Hyaluronate, Butylene Glycol, Caffeine, Dipotassium Glycyrrhizate, Acetyl Hexapeptide-8, Glycereth-26, Alcaligenes Polysaccharides, Trehalose, Lactobacillus Ferment, Maris Sal, Tourmaline, Urea, Sodium PCA, Glycine Soja Protein, Glycosaminoglycans, Glycine Soja Seed Extract, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Caprylyl Glycol, PEG-8, Magnesium Chloride, Calcium Chloride, Sodium Sulfate, Potassium Phosphate, Potassium Nitrate, Pentylene Glycol, Triacetin, Lecithin, PPG-5-Ceteth-20, Jojoba Wax PEG-120 Esters, Polysorbate 20, Polyquaternium-51, Hydroxypropyl Cyclodextrin, Alcohol Denat., Parfum, Limonene, Linalool, Hydroxycitronellal, Citronellol, Geraniol, BHT, Disodium EDTA, Potassium Sorbate, Chlorphenesin, Sorbic Acid, Phenoxyethanol Dimethicone Isononyl Isononanoate Castor Isostearate Succinate Glyceryl Stearate C12-15 Alkyl Benzoate Dimethicone Crosspolymer PEG-33 Behenyl Alcohol PEG-100 Stearate Pentaerythrityl Tetraisostearate Polymethylsilsesquioxane Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Seed Oil Sa These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Dipotassium Glycyrrhizate comes from licorice root. Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties. One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs. Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties. Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. However, more research is needed to support this. Liquiritin is one of the flavone compounds found in licorice. It has been found to help lighten skin by preventing tyrosinase from reacting with tyrosine. When the two react, protein is converted to melanin. Melanin is the substance in your body that gives your features pigmentation. Licorice root is native to Southern Europe and Asia. It has been used in traditional Chinese medicine to help with respiratory issues. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glyceri