Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Roche-Posay Anthelios UV Clear Sunscreen SPF 50 Versus Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50

La Roche-Posay Anthelios UV Clear Sunscreen SPF 50 Versus Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50 Detailed comparison of La Roche-Posay Anthelios UV Clear Sunscreen SPF 50 versus Paula's Choice Resist Youth-Extending Daily Hydrating

This source-based comparison does not add ratings or recommend a winner.

La Roche-Posay Anthelios UV Clear Sunscreen SPF 50 Versus Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50 Detailed comparison of La Roche-Posay Anthelios UV Clear Sunscreen SPF 50 versus Paula's Choice Resist Youth-Extending Daily Hydrating Fluid SPF 50. This chemical sunscreen covers most of the UV range, lighter on the deep UVA that drives aging. This hybrid sunscreen covers the full UV range and blocks ~98% of UVB at SPF 50. Butyl Methoxydibenzoylmethane 3% Homosalate 7% Ethylhexyl Salicylate 5% Octocrylene 7% Water Glycerin C15-19 Alkane Propanediol C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer Tocopherol Azelaic Acid Sodium Stearoyl Glutamate Cetearyl Alcohol Sclerotium Gum Hydroxyacetophenone Caprylyl Glycol Sodium Hydroxide Sodium Starch Octenylsuccinate Glyceryl Stearate Jojoba Esters Helianthus Annuus Seed Wax Hydroxypropyl Starch Phosphate Trisodium Ethylenediamine Disuccinate Pentylene Glycol Diethylhexyl Syringylidenemalonate Cassia Alata Leaf Extract Maltodextrin Caprylic/Capric Triglyceride Polyglycerin-3 Citric Acid Butyl Methoxydibenzoylmethane 3%, Homosalate 7%, Ethylhexyl Salicylate 5%, Octocrylene 7%, Water, Glycerin, C15-19 Alkane, Propanediol, C12-22 Alkyl Acrylate/Hydroxyethylacrylate Copolymer, Tocopherol, Azelaic Acid, Sodium Stearoyl Glutamate, Cetearyl Alcohol, Sclerotium Gum, Hydroxyacetophenone, Caprylyl Glycol, Sodium Hydroxide, Sodium Starch Octenylsuccinate, Glyceryl Stearate, Jojoba Esters, Helianthus Annuus Seed Wax, Hydroxypropyl Starch Phosphate, Trisodium Ethylenediamine Disuccinate, Pentylene Glycol, Diethylhexyl Syringylidenemalonate, Cassia Alata Leaf Extract, Maltodextrin, Caprylic/Capric Triglyceride, Polyglycerin-3, Citric Acid Butyl Methoxydibenzoylmethane 2% Ethylhexyl Methoxycinnamate 7.5% Octocrylene 2% Silica Dimethicone Chamomilla Recutita Flower Extract Vitis Vinifera Seed Extract Camellia Sinensis Leaf Extract Camellia Oleifera Leaf Extract Peucedanum Graveolens Extract Sambucus Nigra Fruit Extract Avena Sativa Bran Extract Punica Granatum Extract Lycium Barbarum Fruit Extract Hydrogenated Lecithin Titanium Dioxide Dimethicone/Vinyl Dimethicone Crosspolymer Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Xanthan Gum Sodium Carbomer Benzyl Alcohol Sodium Benzoate Potassium Sorbate Phenoxyethanol Butyl Methoxydibenzoylmethane 2%, Ethylhexyl Methoxycinnamate 7.5%, Ethylhexyl Salicylate 5%, Octocrylene 2%, Water, Glycerin, Silica, Dimethicone, Tocopherol, Chamomilla Recutita Flower Extract, Vitis Vinifera Seed Extract, Camellia Sinensis Leaf Extract, Camellia Oleifera Leaf Extract, Peucedanum Graveolens Extract, Sambucus Nigra Fruit Extract, Avena Sativa Bran Extract, Punica Granatum Extract, Lycium Barbarum Fruit Extract, Hydrogenated Lecithin, Titanium Dioxide, Dimethicone/Vinyl Dimethicone Crosspolymer, Diethylhexyl Syringylidenemalonate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Sodium Carbomer, Benzyl Alcohol, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Also known as Avobenzone, this ingredient is an oil-soluble used to absorb the full spectrum of UVA rays (peak 357 nm). It's one of the most effective UVA filters available but has a major caveat of photostability: avobenzone is susceptible to photodegradation. This means it can lose efficacy when exposed to sunlight without the help of a stabilizing agent. Studies show antioxidants (like vitamin E or vitamin C) and some UV filters (like octocrylene and Tinosorb S) can meaningfully improve its stability in a formulation. The maximum allowable concentration according to regulation is 3% in the US + Canada, and 5% in the EU, Australia, China, Korea, and ASEAN countries. It has a well-support safety profile: a comprehensive 2025 review found minimal toxicity with no evidence of carcinogenicity. Overall, avobenzone is a safe and regulated ingredient used in sunscreen for over 40 years. Diethylhexyl Syringylidenemalonate (DESM) is a photostabilizer, antioxidant, and SPF booster. One of DESM's main roles is stabilizing UV filters, especially avobenzone. Avobenzone is notoriously unstable when exposed to sunlight. By enhancing the stability of these filters, DESM helps maintain the sunscreen's effectivess through wear. It also helps improve protection against long-wave UVA rays by increasing the wavelength of the formula. Besides enhancing UVA protection, DESM can boost the SPF of high-SPF formulations by up to 5 units. DESM also preserves the color integrity of cosmetic products and helps reduce the chance of yellowing of fading due to light exposure. This ingredient is typically found in concentrations between 0.3% - 0.5%. There are currently no maximum usage limits by regulatory bodies. Though this ingredient is a chemical UV filter, it can often be found in "100% mineral" sunscreens. This is due to regulatory loopholes. Ethylhexyl Salicylate (also called Octisalate or Octyl Salicylate) is an oil-soluble organic UV filter that's been used in sunscreen since the 1950's. It absorbs UVB light in the 280-320 nm range with a peak absorbance around 306 nm. You'll often see it paired with other UV filters to boost overall SPF because octisalate is a fairly week filter on its own. The reason you'll see it so often is because it can help solubilize and stabilize the trickier filters like oxybenzone and avobenzone. Unlike these filters, octisalate has pretty good photostability and doesn't create skin-damaging free radicals when exposed to sunlight. The fatty-alcohol part of the molecule also gives it a light, emollient feel so it doubles as a nice texture enhancer. Usage levels vary around the world: Safety-wise, this ingredient has a pretty reassuring track record. The EU's Scientific Committee on Consumer Products (SCCP) found very low skin penetration in human skin tests and negative results for irritation, phototoxicity, and