Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Roche-Posay Effaclar A.Z. Gel Cream Versus Paula's Choice 10% Azelaic Acid Booster

La Roche-Posay Effaclar A.Z. Gel Cream Versus Paula's Choice 10% Azelaic Acid Booster Detailed comparison of La Roche-Posay Effaclar A.Z. Gel Cream UK versus Paula's Choice 10% Azelaic Acid Booster. This acne moisturizer is formulated around Azelaic Acid and S

This source-based comparison does not add ratings or recommend a winner.

La Roche-Posay Effaclar A.Z. Gel Cream Versus Paula's Choice 10% Azelaic Acid Booster Detailed comparison of La Roche-Posay Effaclar A.Z. Gel Cream UK versus Paula's Choice 10% Azelaic Acid Booster. This acne moisturizer is formulated around Azelaic Acid and Salicylic Acid to clear breakouts and refine skin texture. This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots. Water Azelaic Acid C15-19 Alkane Glycerin Triethyl Citrate Diglycerin Salicylic Acid Panthenol Silica Ammonium Polyacryloyldimethyl Taurate Taraxacum Officinale Rhizome/Root Extract Zinc Gluconate Glyceryl Stearate PEG-100 Stearate Sodium Hyaluronate Sodium Hydroxide Sodium Phosphate Disodium Phosphate Hydroxyethylcellulose Hydroxypropyl Starch Phosphate Tetrasodium Glutamate Diacetate Citric Acid Trisodium Ethylenediamine Disuccinate Pentylene Glycol Polysorbate 60 Parfum Water, Azelaic Acid, C15-19 Alkane, Glycerin, Triethyl Citrate, Diglycerin, Salicylic Acid, Panthenol, Silica, Ammonium Polyacryloyldimethyl Taurate, Taraxacum Officinale Rhizome/Root Extract, Zinc Gluconate, Glyceryl Stearate, PEG-100 Stearate, Sodium Hyaluronate, Sodium Hydroxide, Sodium Phosphate, Disodium Phosphate, Hydroxyethylcellulose, Hydroxypropyl Starch Phosphate, Tetrasodium Glutamate Diacetate, Citric Acid, Trisodium Ethylenediamine Disuccinate, Pentylene Glycol, Polysorbate 60, Parfum C12-15 Alkyl Benzoate Caprylic/Capric Triglyceride Methyl Glucose Sesquistearate Cetearyl Alcohol Dimethicone Adenosine Glycyrrhiza Glabra Root Extract Boerhavia Diffusa Root Extract Allantoin Bisabolol Cyclopentasiloxane Xanthan Gum Sclerotium Gum Propanediol Butylene Glycol Phenoxyethanol Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin. What makes it special? OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription. Here's what each tier does best: Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive. Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive. Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture. This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic. A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier. Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range. Fun fact: The human body also creates Glyceryl Stearate naturally. Salicylic Acid (also known as beta hydroxy acid or BHA) is a well-known ingredient for treating skin that struggles with acne and clogged pores. It exfoliates both the skin's surface and deep within the pores to help clear out buildup, control oil, and reduce inflammation. Unlike AHAs (alpha hydroxy acids), salicylic acid is oil-soluble. This allows it to penetrate into pores which makes it especially effective for treating blackheads and preventing future breakouts. Salicylic acid is also known for its