Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Roche-Posay Effaclar H Moisturizer Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol

La Roche-Posay Effaclar H Moisturizer Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol Detailed comparison of La Roche-Posay Effaclar H Moisturizer versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol. This barrier-repair da

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La Roche-Posay Effaclar H Moisturizer Versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol Detailed comparison of La Roche-Posay Effaclar H Moisturizer versus Paula's Choice Resist Barrier Repair Moisturizer with Retinol. This barrier-repair day moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Retinol and Ceramide NP to strengthen the skin barrier and soften the look of wrinkles. Water Dimethicone Glycerin Propylene Glycol Ethylhexyl Palmitate Squalane Niacinamide Caprylic/Capric Triglyceride Butyrospermum Parkii Butter PEG-100 Stearate Glyceryl Stearate PEG-20 Stearate Carbomer Triethanolamine Dimethicone/Vinyl Dimethicone Crosspolymer Myristyl Malate Phosphonic Acid Ammonium Polyacryloyldimethyl Taurate Hydroxypalmitoyl Sphinganine Caprylyl Glycol Tetrasodium EDTA Xanthan Gum Cetyl Alcohol Tocopherol Phenoxyethanol Parfum Water, Dimethicone, Glycerin, Propylene Glycol, Ethylhexyl Palmitate, Squalane, Niacinamide, Caprylic/Capric Triglyceride, Butyrospermum Parkii Butter, PEG-100 Stearate, Glyceryl Stearate, PEG-20 Stearate, Carbomer, Triethanolamine, Dimethicone/Vinyl Dimethicone Crosspolymer, Myristyl Malate Phosphonic Acid, Ammonium Polyacryloyldimethyl Taurate, Hydroxypalmitoyl Sphinganine, Caprylyl Glycol, Tetrasodium EDTA, Xanthan Gum, Cetyl Alcohol, Tocopherol, Phenoxyethanol, Parfum Dicaprylyl Carbonate Ethylhexyl Stearate Cocoglycerides Sodium Polyacrylate Lecithin Adenosine Palmitoyl Tripeptide-1 Ceramide NP Retinol Punica Granatum Extract Camellia Oleifera Leaf Extract Glycyrrhiza Glabra Root Extract Tetrahydrodiferuloylmethane Tetrahydrodemethoxydiferuloylmethane Tetrahydrobisdemethoxydiferuloylmethane Tocopheryl Acetate Chamomilla Recutita Flower Extract Glycine Soja Seed Extract Glycine Soja Oil Butylene Glycol Glyceryl Polymethacrylate Water, Dicaprylyl Carbonate, Glycerin, Ethylhexyl Stearate, Cocoglycerides, Butyrospermum Parkii Butter, Squalane, Sodium Polyacrylate, Lecithin, Adenosine, Palmitoyl Tripeptide-1, Ceramide NP, Retinol, Punica Granatum Extract, Camellia Oleifera Leaf Extract, Glycyrrhiza Glabra Root Extract, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Tocopheryl Acetate, Chamomilla Recutita Flower Extract, Glycine Soja Seed Extract, Glycine Soja Oil, Butylene Glycol, Propylene Glycol, Glyceryl Polymethacrylate, Xanthan Gum, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula,