Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer Versus Drunk Elephant Protini Powerpeptide Resurfacing Serum

La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer Versus Drunk Elephant Protini Powerpeptide Resurfacing Serum Detailed comparison of La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer versus Drunk Elephant Protini Powerpeptide Resurfacing Ser

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La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer Versus Drunk Elephant Protini Powerpeptide Resurfacing Serum Detailed comparison of La Roche-Posay Pigmentclar Serum Visible Dark Spot Reducer versus Drunk Elephant Protini Powerpeptide Resurfacing Serum. This brightening serum is formulated around Niacinamide and Phenylethyl Resorcinol to fade the look of dark spots and brighten dull-looking skin. This smoothing serum is formulated around Lactic Acid and Sh-Oligopeptide-1 to refine skin texture and soften the look of wrinkles. Water Glycerin Dimethicone Alcohol Denat. Niacinamide Isopropyl Lauroyl Sarcosinate Octyldodecanol PEG-20 Methyl Glucose Sesquistearate Dimethiconol Cetearyl Ethylhexanoate Isohexadecane Sodium Hyaluronate Ginkgo Biloba Leaf Extract Phenylethyl Resorcinol Poloxamer 338 Ammonium Polyacryloyldimethyl Taurate Disodium EDTA Isopropyl Myristate Capryloyl Salicylic Acid Xanthan Gum Ferulic Acid Polysorbate 80 Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Phenoxyethanol CI 77891 Mica Parfum Water, Glycerin, Dimethicone, Alcohol Denat., Niacinamide, Isopropyl Lauroyl Sarcosinate, Octyldodecanol, PEG-20 Methyl Glucose Sesquistearate, Dimethiconol, Cetearyl Ethylhexanoate, Isohexadecane, Sodium Hyaluronate, Ginkgo Biloba Leaf Extract, Phenylethyl Resorcinol, Poloxamer 338, Ammonium Polyacryloyldimethyl Taurate, Disodium EDTA, Isopropyl Myristate, Capryloyl Salicylic Acid, Xanthan Gum, Ferulic Acid, Polysorbate 80, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, CI 77891, Mica, Parfum Lactic Acid Dicaprylyl Carbonate Squalane Sodium Hydroxide Glycine Max Seed Extract Sclerocarya Birrea Seed Oil Camellia Sinensis Seed Oil Sodium PCA Caprylic/Capric Triglyceride Borago Officinalis Seed Oil Tremella Fuciformis Polysaccharide Tocotrienols Sh-Oligopeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-1 Sh-Polypeptide-9 Sh-Polypeptide-11 Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-38 Palmitoyl Hexapeptide-12 Tripeptide-1 Pyrus Malus Fruit Extract Propanediol Panthenol Sodium Hyaluronate Crosspolymer Sodium Lactate PCA Alanine Arginine Glycine Histidine Isoleucine Phenylalanine Proline Serine Threonine Valine Adenosine Nymphaea Alba Root Extract Bacillus/Folic Acid Ferment Filtrate Extract Symphytum Officinale Callus Culture Extract Dextran Oryza Sativa Bran Oil Linoleic Acid Linolenic Acid Butylene Glycol Acetyl Glutamine Coconut Alkanes Coco-Caprylate/Caprate Pentylene Glycol Isomalt Lecithin Aspartic Acid Phytosphingosine Phospholipids Glycine Soja Sterols Tocopherol Citric Acid Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Sodium Benzoate Hydroxypropyl Cyclodextrin Polysorbate 20 Caprylyl Glycol Phenylpropanol Chlorphenesin Carbomer Glyceryl Caprylate Ethylhexylglycerin Water, Glycerin, Lactic Acid, Dicaprylyl Carbonate, Squalane, Sodium Hydroxide, Glycine Max Seed Extract, Sclerocarya Birrea Seed Oil, Camellia Sinensis Seed Oil, Sodium PCA, Caprylic/Capric Triglyceride, Borago Officinalis Seed Oil, Tremella Fuciformis Polysaccharide, Tocotrienols, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-9, Sh-Polypeptide-11, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-38, Palmitoyl Hexapeptide-12, Tripeptide-1, Pyrus Malus Fruit Extract, Propanediol, Sodium Hyaluronate, Panthenol, Sodium Hyaluronate Crosspolymer, Sodium Lactate, PCA, Alanine, Arginine, These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Sodium Hyaluronate is the salt form of hyaluronic acid. It is a long sugar chain that is naturally found in your skin, joints, and connective tissue that maintains hydration and elasticity. In skincare, it works as a humectant. It pulls water from the environment and deeper layers of skin and binds it to the surface. Interestingly, the size of the molecule affects its behavior: Some clinical evidence links low molecular weight versions to improved wrinkle depth, elasticity, anti-inflammatory effects, and barrier repair. Many serums use a blend of both weights so you can