La Roche-Posay Toleriane Double Repair Face Moisturizer Versus Paula's Choice Omega+ Complex Moisturizer

La Roche-Posay Toleriane Double Repair Face Moisturizer Versus Paula's Choice Omega+ Complex Moisturizer Detailed comparison of La Roche-Posay Toleriane Double Repair Face Moisturizer versus Paula's Choice Omega+ Complex Moisturizer. This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Butyrospermum Parkii Butter and Linoleic Acid to strengthen the skin barrier and hydrate skin. Water Glycerin Squalane Dimethicone Zea Mays Starch Niacinamide Ammonium Polyacryloyldimethyl Taurate Myristyl Myristate Stearic Acid Ceramide NP Potassium Cetyl Phosphate Glyceryl Stearate Se Sodium Hydroxide Myristic Acid Palmitic Acid Capryloyl Glycine Caprylyl Glycol Xanthan Gum Water, Glycerin, Squalane, Dimethicone, Zea Mays Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Stearic Acid, Ceramide NP, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Capryloyl Glycine, Caprylyl Glycol, Xanthan Gum Butyrospermum Parkii Butter Ceteareth-6 Olivate Butylene Glycol C13-15 Alkane Glyceryl Stearate Polyglyceryl-4 Laurate Decyl Oleate Linum Usitatissimum Seed Oil Salvia Hispanica Seed Oil Olea Europaea Fruit Oil Passiflora Edulis Seed Oil Borago Officinalis Seed Oil Hydrogenated Olive Oil Psidium Guajava Fruit Extract Olea Europaea Oil Unsaponifiables Limnanthes Alba Seed Oil Linoleic Acid Linolenic Acid Oleic Acid Euterpe Oleracea Sterols Ceramide AP Ceramide EOP Serine Alanine Glycine Proline Lysine Hcl Threonine Arginine Cholesterol Phytosphingosine Anastatica Hierochuntica Extract Lecithin Sodium Hyaluronate Sodium Lactate Boerhavia Diffusa Root Extract Adenosine Phytic Acid Glutamic Acid Betaine Pullulan PCA Sodium PCA Carbomer Sodium Polyacrylate Starch Sclerotium Gum Sodium Lauroyl Lactylate Phenoxyethanol Ethylhexylglycerin Water, Butyrospermum Parkii Butter, Ceteareth-6 Olivate, Butylene Glycol, C13-15 Alkane, Glycerin, Glyceryl Stearate, Polyglyceryl-4 Laurate, Decyl Oleate, Linum Usitatissimum Seed Oil, Salvia Hispanica Seed Oil, Olea Europaea Fruit Oil, Passiflora Edulis Seed Oil, Borago Officinalis Seed Oil, Hydrogenated Olive Oil, Psidium Guajava Fruit Extract, Olea Europaea Oil Unsaponifiables, Limnanthes Alba Seed Oil, Linoleic Acid, Linolenic Acid, Oleic Acid, Euterpe Oleracea Sterols, Ceramide AP, Ceramide EOP, Ceramide NP, Serine, Alanine, Glycine, Proline, Lysine Hcl, Threonine, Arginine, Squalane, Cholesterol, Phytosphingosine, Anastatica Hierochuntica Extract, Lecithin, Sodium Hyaluronate, Sodium Lactate, Boerhavia Diffusa Root Extract, Adenosine, Phytic Acid, Glutamic Acid, Betaine, Pullulan, PCA, Sodium PCA, Carbomer, Sodium Polyacrylate Starch, Sclerotium Gum, Xanthan Gum, Sodium Lauroyl Lactylate, Phenoxyethanol, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum). It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores. This is due to how structurally similar it is to what your skin already produces. Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer. Research shows it has antioxidant capabilities that help protect against stressors like UV exposure, specifically UVA induced oxidative stress. This study also found that it supports collagen biosynthesis in human dermal fibroblasts. No clinical study has reported significant adverse effects and irritation reactions are very rare from this ingredient (even at 10