Lancôme Rénergie H.P.N. 300-Peptide Cream Versus Paula's Choice Resist Anti-Aging Clear Skin Hydrator

Lancôme Rénergie H.P.N. 300-Peptide Cream Versus Paula's Choice Resist Anti-Aging Clear Skin Hydrator Detailed comparison of Lancôme Rénergie H.P.N. 300-Peptide Cream versus Paula's Choice Resist Anti-Aging Clear Skin Hydrator. This anti-aging moisturizer is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture. This anti-aging moisturizer is formulated around Sodium Ascorbyl Phosphate and Niacinamide to soften the look of wrinkles and balance excess oil. Water Glycerin Dimethicone Cetearyl Alcohol Theobroma Grandiflorum Seed Butter Alcohol Denat. Cetearyl Isononanoate Niacinamide Glyceryl Stearate PEG-100 Stearate Isopropyl Palmitate Octyldodecanol Cyclodextrin Hydrolyzed Lupine Protein Pisum Sativum Extract Adenosine Capryloyl Salicylic Acid Hydrolyzed Hyaluronic Acid Hydrolyzed Linseed Extract Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Trisodium Ethylenediamine Disuccinate Tocopheryl Acetate Cera Alba Orbignya Oleifera Seed Oil Simmondsia Chinensis Butter Cetearyl Glucoside Citric Acid Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Polysorbate 60 Potassium Cetyl Phosphate Sorbitan Isostearate Tocopherol Dimethicone/Polyglycerin-3 Crosspolymer Benzyl Alcohol Geraniol Limonene Chlorphenesin Dipropylene Glycol Phenoxyethanol Sodium Benzoate Parfum Water, Glycerin, Dimethicone, Cetearyl Alcohol, Theobroma Grandiflorum Seed Butter, Alcohol Denat., Cetearyl Isononanoate, Niacinamide, Glyceryl Stearate, PEG-100 Stearate, Isopropyl Palmitate, Octyldodecanol, Cyclodextrin, Hydrolyzed Lupine Protein, Pisum Sativum Extract, Adenosine, Capryloyl Salicylic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Linseed Extract, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Trisodium Ethylenediamine Disuccinate, Tocopheryl Acetate, Cera Alba, Orbignya Oleifera Seed Oil, Simmondsia Chinensis Butter, Cetearyl Glucoside, Citric Acid, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Potassium Cetyl Phosphate, Sorbitan Isostearate, Tocopherol, Dimethicone/Polyglycerin-3 Crosspolymer, Benzyl Alcohol, Geraniol, Limonene, Chlorphenesin, Dipropylene Glycol, Phenoxyethanol, Sodium Benzoate, Parfum Cyclopentasiloxane Octyldodecyl Neopentanoate Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer Sodium Ascorbyl Phosphate Cetyl Alcohol Butylene Glycol Epigallocatechin Gallate Glucose Oxidase Lactoperoxidase Boerhavia Diffusa Root Extract Cocos Nucifera Fruit Extract Lactobacillus Polysilicone-11 Sodium Chloride Potassium Thiocyanate Glucose Xanthan Gum Ceteareth-20 Decyl Glucoside Water, Cyclopentasiloxane, Octyldodecyl Neopentanoate, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Glycerin, Sodium Ascorbyl Phosphate, Cetyl Alcohol, Niacinamide, Dimethicone, Cetearyl Alcohol, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Adenosine, Epigallocatechin Gallate, Glucose Oxidase, Lactoperoxidase, Boerhavia Diffusa Root Extract, Cocos Nucifera Fruit Extract, Lactobacillus, Polysilicone-11, Sodium Chloride, Potassium Thiocyanate, Glucose, Xanthan Gum, Ceteareth-20, Decyl Glucoside, Citric Acid, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elasticity, and hydration. On concentrations, South Korea's Ministry of Food and Drug Safety has set 0.04% as the approved functional anti-wrinkle level. You'll typically see this ingredient used somewhere in the 0.04-0.1% range since it works at low doses. This ingredient has been found safe for cosmetics with the data showing no irritation or sensitization. Overall, this is a great ingredient for any anti-aging routine and has no photosensitizing effect, so it suits both AM and PM use. Cetearyl alcohol is a waxy mixture of two fatty alcohols: cetyl alcohol and stearyl alcohol. It is an emollient and emulsifier. Despite having "alcohol" in its name, it has nothing to do with drying solvent alcohols; the FDA also allows "alcohol-free" products to contain fatty alcohols like this ingredient. It plays several roles in a formula: Typical use levels for this ingredient sit around 1-10% and the Cosmetic Ingredient Review Expert Panel has affirmed safety at concentrations up to 25% in leave-on products. Multiple assessments have found it to be non-irritating and non-sensitizing to most people. However, there have been some cases of allergic contact dermatitis in patients with chronically compromised skin barriers. Cetearyl alcohol has a comedogenic rating of 2 and irritancy rating of 1. Both of these numbers come from the 1989 study that used rabbit ears; a "2" means mildly comedogenic and a "1" means low irritancy. Here's the catch: rabbit skin is more sensitive than human skin and throws a lot of false positives. A 1996 reappraisal found that ingredients rated 1-2 in the rabbit ear tests are generally safe for humans. Remember comedogenic ratings are unable to assess the entire formula of a product or how it will react on your skin. Just be sure to patch test if you are unsure about certain ingredients. This ingredient is not fungal acne safe. Cetearyl alcohol is a fatty alcohol with chain le