Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Laneige Lip Treatment Balm Versus Mac Cosmetics Prep + Prime Lip Primer

Laneige Lip Treatment Balm Versus Mac Cosmetics Prep + Prime Lip Primer Detailed comparison of Laneige Lip Treatment Balm versus Mac Cosmetics Prep + Prime Lip Primer. This anti-aging lip moisturizer is formulated around Butyrospermum Parkii Butter and Adenosi

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Laneige Lip Treatment Balm Versus Mac Cosmetics Prep + Prime Lip Primer Detailed comparison of Laneige Lip Treatment Balm versus Mac Cosmetics Prep + Prime Lip Primer. This anti-aging lip moisturizer is formulated around Butyrospermum Parkii Butter and Adenosine to soften the look of wrinkles and hydrate lips. This smoothing lip moisturizer is formulated around Tocopherol and Palmitoyl Tripeptide-1 to refine skin texture and soften the look of wrinkles. Diisostearyl Malate Hydrogenated Polyisobutene Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate Polybutene Hydrogenated Poly(C6-14 Olefin) Butyrospermum Parkii Butter Cera Microcristallina Synthetic Wax Ethylene/Propylene/Styrene Copolymer Sucrose Tetrastearate Triacetate Mica CI 77891 Euphorbia Cerifera Wax Ethylhexyl Palmitate Parfum Candelilla Wax Esters Astrocaryum Murumuru Seed Butter Tribehenin Menthoxypropanediol Glycerin Cocos Nucifera Oil Oenothera Biennis Oil Lecithin Butylene/Ethylene/Styrene Copolymer Sorbitan Isostearate Copernicia Cerifera Cera Dehydroacetic Acid Adenosine Tocopherol Lactic Acid Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Palmitoyl Tripeptide-1 Diisostearyl Malate, Hydrogenated Polyisobutene, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Polybutene, Hydrogenated Poly(C6-14 Olefin), Butyrospermum Parkii Butter, Cera Microcristallina, Synthetic Wax, Ethylene/Propylene/Styrene Copolymer, Sucrose Tetrastearate Triacetate, Mica, CI 77891, Euphorbia Cerifera Wax, Ethylhexyl Palmitate, Parfum, Candelilla Wax Esters, Astrocaryum Murumuru Seed Butter, Tribehenin, Menthoxypropanediol, Glycerin, Cocos Nucifera Oil, Oenothera Biennis Oil, Lecithin, Butylene/Ethylene/Styrene Copolymer, Sorbitan Isostearate, Copernicia Cerifera Cera, Dehydroacetic Acid, Adenosine, Tocopherol, Lactic Acid, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Palmitoyl Tripeptide-1 Cyclopentasiloxane Octyldodecyl Stearoyl Stearate Ceresin Microcrystalline Wax Ozokerite Disteardimonium Hectorite Vanillin Cyclopentasiloxane, Octyldodecyl Stearoyl Stearate, Ceresin, Polybutene, Microcrystalline Wax, Ozokerite, Tocopherol, Ethylhexyl Palmitate, Tribehenin, Palmitoyl Tripeptide-1, Disteardimonium Hectorite, Sorbitan Isostearate, Vanillin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ethylhexyl Palmitate, also known as octyl palmitate, is created from 2-ethylhexyl alcohol and palmitic acid. In cosmetics, it plays many roles: One thing worth noting: a controlled study found this ingredient applied under occlusion to acne-prone subjects increased microcomedones. Just keep in mind this was under occlusive conditions and don't reflect how most products are used day-to-day. For most people, this is a well-tolerated and lightweight ingredient. This ingredient may not be fungal acne safe because it is an ester of palmitic acid, a C16 fatty acid that falls within the C11-24 range that Malassezia can metabolize. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid. In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing. Human clinical data is promising, but modest: A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm. A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks. You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex. Fungal acne note: Usually a palmitic acid component can feed Malassezia in unbound form, but here is is covalently bonded to the peptide. This means it is very difficult for Malassezia to access, and therefore very unlikely to cause fungal acne. Polybutene is used to help control the viscosity of a product. This just means it helps adjusts the texture. It is a polymer and does not get absorbed into the skin due to its large size. Studies found this ingredient did not irritate skin in concentrations below 15%. Sorbitan Isostearate is an emulsifer. It is created from isostearic acid and sorbitol. As an emulsifier, it keeps the water and oil ingredients from separating. This keeps formulas stable and smooth. In a 24 hour occlusive patch test on 56 subjects, 10% sorbitan isostearate was completely non-irritating. Most formulas use less than 10%. Because it's a fatty acid ester, it may not be fungal acne safe since the Malassezia yeast can utilize it as a nutrient source. Tocopherol is a fat-soluble antioxidant known as V