Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Mario Badescu Protein Night Cream Versus DRMTLGY Peptide Night Cream

Mario Badescu Protein Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Mario Badescu Protein Night Cream versus DRMTLGY Peptide Night Cream. This night moisturizer is formulated around Oryza Sativa Bran Oil and Retinyl Palmitate to hydrate

This source-based comparison does not add ratings or recommend a winner.

Mario Badescu Protein Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Mario Badescu Protein Night Cream versus DRMTLGY Peptide Night Cream. This night moisturizer is formulated around Oryza Sativa Bran Oil and Retinyl Palmitate to hydrate skin. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Petrolatum Oryza Sativa Bran Oil Glycerin Ethylhexyl Palmitate Cetyl Alcohol C10-30 Cholesterol/Lanosterol Esters Cera Alba Dimethicone Olus Oil Stearic Acid Propylene Glycol Oligopeptide-5 Retinyl Palmitate Soluble Collagen Zea Mays Oil Sodium Borate Triethanolamine Diazolidinyl Urea Sodium Benzoate Propylparaben Methylparaben Glyceryl Acrylate/Acrylic Acid Copolymer Parfum Phenoxyethanol Tocopherol Hexyl Cinnamal Water, Petrolatum, Oryza Sativa Bran Oil, Glycerin, Ethylhexyl Palmitate, Cetyl Alcohol, C10-30 Cholesterol/Lanosterol Esters, Cera Alba, Dimethicone, Olus Oil, Stearic Acid, Propylene Glycol, Oligopeptide-5, Retinyl Palmitate, Soluble Collagen, Zea Mays Oil, Sodium Borate, Triethanolamine, Diazolidinyl Urea, Sodium Benzoate, Propylparaben, Methylparaben, Glyceryl Acrylate/Acrylic Acid Copolymer, Parfum, Phenoxyethanol, Tocopherol, Hexyl Cinnamal Glyceryl Stearate Propanediol C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Ethylhexylglycerin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Xanthan Gum Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. Its main roles are: Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols. This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethyl