Peptide Skincare & BeautySkin science and ingredient guides

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MediCube Hyaluronic Multi Peptide Serum Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence

MediCube Hyaluronic Multi Peptide Serum Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence Detailed comparison of MediCube Hyaluronic Multi Peptide Serum versus Numbuzin 9+ NAD Bio Lifting-Sil Essence. This hydrating serum is formulated around Niacinamide and Sodi

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MediCube Hyaluronic Multi Peptide Serum Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence Detailed comparison of MediCube Hyaluronic Multi Peptide Serum versus Numbuzin 9+ NAD Bio Lifting-Sil Essence. This hydrating serum is formulated around Niacinamide and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles. This anti-aging essence is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture. Water Neopentyl Glycol Dicaprate Propanediol Glycerin 1,2-Hexanediol Niacinamide Trehalose Glyceryl Glucoside Sorbitol Sodium Hyaluronate Sodium Chloride Panthenol Ethylhexylglycerin Allantoin Adenosine Disodium EDTA Glucose Melia Azadirachta Leaf Extract Melia Azadirachta Flower Extract Butylene Glycol Alpha-Arbutin Squalane Coccinia Indica Fruit Extract Solanum Melongena Fruit Extract Sodium DNA Aloe Barbadensis Flower Extract Citrus Aurantium Bergamia Fruit Oil Sodium Hyaluronate Crosspolymer Ocimum Sanctum Leaf Extract Simmondsia Chinensis Seed Oil Corallina Officinalis Extract Curcuma Longa Root Extract Acetyl Hexapeptide-8 Acetyl Tetrapeptide-3 Arginine/Lysine Polypeptide Collagen Extract Copper Tripeptide-1 Dipeptide-2 Hexapeptide-11 Nonapeptide-1 Oligopeptide-1 Palmitoyl Hexapeptide-12 Palmitoyl Pentapeptide-4 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Tripeptide-1 Hyaluronic Acid Hydrolyzed Hyaluronic Acid Hydrolyzed Sodium Hyaluronate Hydroxypropyltrimonium Hyaluronate Potassium Hyaluronate Pentylene Glycol Sodium Acetylated Hyaluronate Water, Neopentyl Glycol Dicaprate, Propanediol, Glycerin, 1,2-Hexanediol, Niacinamide, Trehalose, Glyceryl Glucoside, Sorbitol, Sodium Hyaluronate, Sodium Chloride, Panthenol, Ethylhexylglycerin, Allantoin, Adenosine, Disodium EDTA, Glucose, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Butylene Glycol, Alpha-Arbutin, Squalane, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Sodium DNA, Aloe Barbadensis Flower Extract, Citrus Aurantium Bergamia Fruit Oil, Sodium Hyaluronate Crosspolymer, Ocimum Sanctum Leaf Extract, Simmondsia Chinensis Seed Oil, Corallina Officinalis Extract, Curcuma Longa Root Extract, Acetyl Hexapeptide-8, Acetyl Tetrapeptide-3, Arginine/Lysine Polypeptide, Collagen Extract, Copper Tripeptide-1, Dipeptide-2, Hexapeptide-11, Nonapeptide-1, Oligopeptide-1, Palmitoyl Hexapeptide-12, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Tripeptide-1, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Pentylene Glycol, Sodium Acetylated Hyaluronate Hydrogenated Poly(C6-14 Olefin) Polyglycerin-3 Pentaerythrityl Tetraethylhexanoate Dimethicone Methylpropanediol Cetearyl Alcohol Glyceryl Stearate Hydrogenated Vegetable Oil Polyglyceryl-3 Methylglucose Distearate Butyrospermum Parkii Butter Dimethicone Crosspolymer Ammonium Acryloyldimethyltaurate/Vp Copolymer Sodium Polyacrylate Hydrogenated Lecithin Carbomer Xanthan Gum Tromethamine Palmitic Acid Stearic Acid Sodium Phytate Cholesterol Adenosine Triphosphate Hydroxypropyl Cyclodextrin Nicotinamide Adenine Dinucleotide Beta-Glucan Tocopherol Palmitoyl Tripeptide-5 Copper Gluconate Saccharomyces/Copper Ferment Saccharomyces/Iron Ferment Saccharomyces/Magnesium Ferment Saccharomyces/Silicon Ferment Saccharomyces/Zinc Ferment Capryloyl Dipeptide-17 Thioctic Acid Leuconostoc/Radish Root Ferment Filtrat These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. This biometic peptide is designed to support hair growth. According to a manufacturer, it stimulates hair growth by: The manufacturer has found combining this ingredient with red clover extract (Capixyl) boosted benefits. Not only does it enforce the scalp's extracellular matrix, it also inhibits the enzyme that creates DHT, a hormone that leads to hair loss. While this ingredient is promising, more research is still needed to confirm its full effectiveness. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A later study using Adenosine-loaded dissolving microneedle patches reported gains in wrinkle depth, dermal density, elas