Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

MediCube Triple Collagen Cream Versus DRMTLGY Peptide Night Cream

MediCube Triple Collagen Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of MediCube Triple Collagen Cream versus DRMTLGY Peptide Night Cream. This anti-aging moisturizer is formulated around Niacinamide and Collagen Extract to soften the look of

This source-based comparison does not add ratings or recommend a winner.

MediCube Triple Collagen Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of MediCube Triple Collagen Cream versus DRMTLGY Peptide Night Cream. This anti-aging moisturizer is formulated around Niacinamide and Collagen Extract to soften the look of wrinkles and hydrate skin. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Glycerin Dipropylene Glycol Cetearyl Alcohol Cyclopentasiloxane Caprylic/Capric Triglyceride Triethylhexanoin Hydrogenated Polydecene 1,2-Hexanediol Niacinamide Hydrogenated Poly(C6-14 Olefin) Cyclohexasiloxane Glyceryl Stearate Se Dioscorea Japonica Root Extract Aesculus Hippocastanum Extract Laminaria Japonica Extract Eclipta Prostrata Leaf Extract Collagen Extract Hydrogenated Lecithin Argania Spinosa Kernel Oil Sodium Hyaluronate Cetearyl Olivate C12-16 Alcohols Dimethicone Glyceryl Stearate PEG-100 Stearate Microcrystalline Cellulose Cetearyl Glucoside Sorbitan Olivate Fructose Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Butylene Glycol Squalane Palmitic Acid Betaine Cellulose Gum Hydrolyzed Corn Starch Polysorbate 60 Ethylhexylglycerin Adenosine Hydrogenated Polyisobutene Beta-Glucan Alcohol Disodium EDTA Isononyl Isononanoate Polyglyceryl-10 Stearate Sorbitan Isostearate Sucrose Stearic Acid Butyrospermum Parkii Butter Polyglyceryl-2 Dipolyhydroxystearate Fructooligosaccharides Inulin Lauryl Carbamate Hydrolyzed Hyaluronic Acid Citric Acid Disodium Stearoyl Glutamate Collagen Hydrolyzed Elastin Hyaluronic Acid Tocopherol Leuconostoc/Radish Root Ferment Filtrate Parfum Potassium Sorbate Linalool Benzyl Salicylate Limonene Hydroxycitronellal Water, Glycerin, Dipropylene Glycol, Cetearyl Alcohol, Cyclopentasiloxane, Caprylic/Capric Triglyceride, Triethylhexanoin, Hydrogenated Polydecene, 1,2-Hexanediol, Niacinamide, Hydrogenated Poly(C6-14 Olefin), Cyclohexasiloxane, Glyceryl Stearate Se, Dioscorea Japonica Root Extract, Aesculus Hippocastanum Extract, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Collagen Extract, Hydrogenated Lecithin, Argania Spinosa Kernel Oil, Sodium Hyaluronate, Cetearyl Olivate, C12-16 Alcohols, Dimethicone, Glyceryl Stearate, PEG-100 Stearate, Microcrystalline Cellulose, Cetearyl Glucoside, Sorbitan Olivate, Fructose, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Butylene Glycol, Squalane, Palmitic Acid, Betaine, Cellulose Gum, Hydrolyzed Corn Starch, Polysorbate 60, Ethylhexylglycerin, Adenosine, Hydrogenated Polyisobutene, Beta-Glucan, Alcohol, Disodium EDTA, Isononyl Isononanoate, Polyglyceryl-10 Stearate, Sorbitan Isostearate, Sucrose, Stearic Acid, Butyrospermum Parkii Butter, Polyglyceryl-2 Dipolyhydroxystearate, Fructooligosaccharides, Inulin Lauryl Carbamate, Hydrolyzed Hyaluronic Acid, Citric Acid, Disodium Stearoyl Glutamate, Collagen, Hydrolyzed Elastin, Hyaluronic Acid, Tocopherol, Leuconostoc/Radish Root Ferment Filtrate, Parfum, Potassium Sorbate, Linalool, Benzyl Salicylate, Limonene, Hydroxycitronellal Propanediol C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Cetyl Alcohol Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Palmitoyl Tetrapeptide-7 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosin Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What