Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

MediCube Triple Collagen Serum Versus AXIS - Y Dark Spot Correcting Glow Serum

MediCube Triple Collagen Serum Versus AXIS - Y Dark Spot Correcting Glow Serum Detailed comparison of MediCube Triple Collagen Serum versus AXIS - Y Dark Spot Correcting Glow Serum. This anti-aging serum is formulated around Niacinamide and Adenosine to soften

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MediCube Triple Collagen Serum Versus AXIS - Y Dark Spot Correcting Glow Serum Detailed comparison of MediCube Triple Collagen Serum versus AXIS - Y Dark Spot Correcting Glow Serum. This anti-aging serum is formulated around Niacinamide and Adenosine to soften the look of wrinkles. This brightening serum is formulated around Niacinamide and Squalane to fade the look of dark spots and brighten dull-looking skin. Sea Water Glycerin Butylene Glycol Cetyl Ethylhexanoate 1,2-Hexanediol Alcohol Denat. Niacinamide Glycereth-26 Adenosine Hydrolyzed Collagen Hyaluronic Acid Hydrolyzed Hyaluronic Acid Sodium Hyaluronate Soluble Collagen Collagen Extract Atelocollagen Propanediol Cyclopentasiloxane Trehalose Carbomer Cetearyl Olivate Tromethamine Cyclohexasiloxane Sorbitan Olivate Ethylhexylglycerin Disodium EDTA Dimethicone Parfum Sea Water, Glycerin, Butylene Glycol, Cetyl Ethylhexanoate, 1,2-Hexanediol, Alcohol Denat., Niacinamide, Glycereth-26, Adenosine, Hydrolyzed Collagen, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Sodium Hyaluronate, Soluble Collagen, Collagen Extract, Atelocollagen, Propanediol, Cyclopentasiloxane, Trehalose, Carbomer, Cetearyl Olivate, Tromethamine, Cyclohexasiloxane, Sorbitan Olivate, Ethylhexylglycerin, Disodium EDTA, Dimethicone, Parfum Water Erythritol Squalane Oryza Sativa Bran Extract Calendula Officinalis Flower Extract Carica Papaya Fruit Extract Hippophae Rhamnoides Fruit Extract Malpighia Glabra Fruit Extract Polyglyceryl-10 Laurate Chlorphenesin Arginine Glutathione Hydroxypropyl Cyclodextrin Hydroxyethylcellulose Allantoin Rosmarinus Officinalis Leaf Oil Water, Glycerin, Niacinamide, Sodium Hyaluronate, Propanediol, Erythritol, Butylene Glycol, Squalane, Oryza Sativa Bran Extract, Calendula Officinalis Flower Extract, Carica Papaya Fruit Extract, Hippophae Rhamnoides Fruit Extract, Malpighia Glabra Fruit Extract, Polyglyceryl-10 Laurate, Chlorphenesin, Arginine, Ethylhexylglycerin, Carbomer, Glutathione, 1,2-Hexanediol, Hydroxypropyl Cyclodextrin, Disodium EDTA, Hydroxyethylcellulose, Allantoin, Rosmarinus Officinalis Leaf Oil These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes