Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Medik8 Bakuchiol Peptides Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment

Medik8 Bakuchiol Peptides Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Detailed comparison of Medik8 Bakuchiol Peptides versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment. This anti-aging serum is formulated around Bak

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Medik8 Bakuchiol Peptides Versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Detailed comparison of Medik8 Bakuchiol Peptides versus Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment. This anti-aging serum is formulated around Bakuchiol and Centella Asiatica Leaf Extract to soften the look of wrinkles and calm redness. This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Caprylic/Capric Triglyceride Helianthus Annuus Seed Oil Bakuchiol Krameria Triandra Root Extract Plukenetia Volubilis Seed Oil Moringa Oleifera Seed Oil Tocopherol Centella Asiatica Leaf Extract Aloe Barbadensis Flower Extract Corallina Officinalis Extract Coccinia Indica Fruit Extract Solanum Melongena Fruit Extract Simmondsia Chinensis Seed Oil Curcuma Longa Root Extract Ocimum Basilicum Flower/Leaf Extract Ocimum Sanctum Leaf Extract Eclipta Prostrata Extract Melia Azadirachta Leaf Extract Melia Azadirachta Flower Extract Undecylenoyl Phenylalanine Olea Europaea Fruit Oil Caprylic/Capric Triglyceride, Helianthus Annuus Seed Oil, Bakuchiol, Krameria Triandra Root Extract, Plukenetia Volubilis Seed Oil, Moringa Oleifera Seed Oil, Tocopherol, Centella Asiatica Leaf Extract, Aloe Barbadensis Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Solanum Melongena Fruit Extract, Simmondsia Chinensis Seed Oil, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Ocimum Sanctum Leaf Extract, Eclipta Prostrata Extract, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Undecylenoyl Phenylalanine, Olea Europaea Fruit Oil Water Dimethicone Pentaerythrityl Tetraisostearate Isononyl Isononanoate Butylene Glycol Arachidyl Alcohol Glyceryl Polymethacrylate Dimethicone Crosspolymer Behenyl Alcohol Glycerin PEG-75 Shea Butter Glycerides Glyceryl Stearate C12-15 Alkyl Benzoate Polysorbate 20 Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Sodium Hyaluronate Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Salix Alba Bark Extract Glycine Soja Sterols Lecithin Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Palmitoyl Tripeptide-1 Sodium Hydroxide Tribehenin Caprylyl Glycol Dipeptide-2 Polygonum Cuspidatum Root Extract PEG-10 Phytosterol PEG-8 Magnesium Aluminum Silicate Arachidyl Glucoside Chrysin Pentylene Glycol Sodium Acrylates Copolymer Steareth-20 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol Coco-Glucoside Hesperidin Methyl Chalcone N-Hydroxysuccinimide Disodium EDTA Phenoxyethanol Benzoic Acid Ethylhexylglycerin Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extrac These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Bakuchiol is a plant-derived antioxidant from the seeds of the Psoralea corylifolia plant. It has antimicrobial, emollient, skin conditioning, and antioxidant properties. You'll likely see it called a "retinol replacement" but the two are technically not related. This is because bakuchiol is able to flip many of the same switches in your skin cells to tell them to: 1) produce more collagen (type I, III, and IV) 2) activate the same genes retinoids do Unlike retinoids, this ingredient will not increase photosensitivity and is safe to use during pregnancy (but please still check in with your doctor!). The flagship clinical trial from Dhaliwal et al. 2019 found 0.5% bakuchiol (twice daily) and 0.5% retinol (once daily) reduced wrinkles and hyperpigmentation equally, but bakuchiol had significantly less irritation. Systematic reviews also back this up: Bakuchiol is comparable to retinol for photoaging but with better tolerability. It also has mild antibacterial properties against Cutibacterium acnes and antifungal activity in vitro against Candida and dermatophytes. The reason bakuchiol works well is due to its structure; it is a meroterpene phenol, or a hybrid molecule. The phenol half acts as an antioxidant while the terpene half is fat-loving. This helps the molecule slip through the skin barrier. This ingredient is usually used between 0.5-2%. Only one case of contact dermatitis has ever been reported for this ingredient.