Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Medik8 Liquid Peptides Versus DRMTLGY Peptide Night Cream

Medik8 Liquid Peptides Versus DRMTLGY Peptide Night Cream Detailed comparison of Medik8 Liquid Peptides versus DRMTLGY Peptide Night Cream. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refin

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Medik8 Liquid Peptides Versus DRMTLGY Peptide Night Cream Detailed comparison of Medik8 Liquid Peptides versus DRMTLGY Peptide Night Cream. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Glycerin Butylene Glycol Inulin Sodium Hyaluronate Panthenol Alpha-Glucan Oligosaccharide Carnosine Carbomer Polysorbate 20 Caprylyl Glycol Phenoxyethanol Hydroxypropyl Cyclodextrin Dunaliella Salina Extract Ethylhexylglycerin Citric Acid Palmitoyl Tripeptide-5 Sodium Benzoate Acetyl Hexapeptide-8 Tetrapeptide-21 Pentapeptide-18 Palmitoyl Tripeptide-1 Pantolactone Palmitoyl Tripeptide-38 Palmitoyl Tetrapeptide-7 Glyceryl Caprylate Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Phenylpropanol Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Potassium Sorbate Xanthan Gum Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum Glyceryl Stearate Propanediol C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Butyrospermum Parkii Butter Caprylic/Capric Triglyceride Cetyl Alcohol Dimethicone PEG-100 Stearate Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Tocopherol Glycol Distearate Potassium Cetyl Phosphate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Dextran Magnesium Chloride Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Palmitoyl Tetrapeptide-7 (formerly Palmitoyl Tetrapeptide-3) is a synthetic peptide. Its main job is to fight what researchers call "inflammaging". "Inflammaging" is the slow, low-grade chronic inflammation that quietly breaks down collagen as we age. This ingredient calms down a specific inflammation signal in your skin cells (called IL-6). When left unchecked, this signal triggers enzymes that break dow