Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Medik8 Liquid Peptides Versus Mizon Peptide 500

Medik8 Liquid Peptides Versus Mizon Peptide 500 Detailed comparison of Medik8 Liquid Peptides versus Mizon Peptide 500. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This

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Medik8 Liquid Peptides Versus Mizon Peptide 500 Detailed comparison of Medik8 Liquid Peptides versus Mizon Peptide 500. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Sodium Hyaluronate and Copper Tripeptide-1 to soften the look of wrinkles and hydrate skin. Water Glycerin Butylene Glycol Inulin Sodium Hyaluronate Panthenol Alpha-Glucan Oligosaccharide Carnosine Carbomer Polysorbate 20 Caprylyl Glycol Phenoxyethanol Hydroxypropyl Cyclodextrin Dunaliella Salina Extract Ethylhexylglycerin Citric Acid Palmitoyl Tripeptide-5 Sodium Benzoate Acetyl Hexapeptide-8 Tetrapeptide-21 Pentapeptide-18 Palmitoyl Tripeptide-1 Pantolactone Palmitoyl Tripeptide-38 Palmitoyl Tetrapeptide-7 Glyceryl Caprylate Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Phenylpropanol Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Potassium Sorbate Xanthan Gum Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum Methylpropanediol 1,2-Hexanediol Polyglyceryl-10 Oleate Copper Tripeptide-1 Adenosine Disodium EDTA Biosaccharide Gum-1 Beta-Glucan Glycine Tocopherol Serine Glutamic Acid Houttuynia Cordata Extract Centella Asiatica Extract Hydrolyzed Hyaluronic Acid Hydrolyzed Sodium Hyaluronate Hyaluronic Acid Hydroxypropyltrimonium Hyaluronate Potassium Hyaluronate Aspartic Acid Leucine Pentylene Glycol Alanine Lysine Arginine Tyrosine Phenylalanine Threonine Proline Valine Isoleucine Sodium Sodium Hyaluronate Crosspolymer Histidine Methionine Cysteine Sodium Acetylated Hyaluronate Phosphatidylcholine Sh-Oligopeptide-1 Oligopeptide-29 Oligopeptide-32 Palmitoyl Pentapeptide-4 Sh-Polypeptide-1 Sh-Oligopeptide-2 Sh-Polypeptide-22 Water, Methylpropanediol, Butylene Glycol, 1,2-Hexanediol, Polyglyceryl-10 Oleate, Ethylhexylglycerin, Sodium Hyaluronate, Copper Tripeptide-1, Adenosine, Disodium EDTA, Biosaccharide Gum-1, Beta-Glucan, Glycine, Tocopherol, Serine, Glutamic Acid, Houttuynia Cordata Extract, Centella Asiatica Extract, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Aspartic Acid, Leucine, Pentylene Glycol, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Sodium, Sodium Hyaluronate Crosspolymer, Histidine, Methionine, Cysteine, Sodium Acetylated Hyaluronate, Phosphatidylcholine, Acetyl Hexapeptide-8, Sh-Oligopeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl Pentapeptide-4, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-22, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredi