Medik8 Liquid Peptides Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence

Medik8 Liquid Peptides Versus Numbuzin 9+ NAD Bio Lifting-Sil Essence Detailed comparison of Medik8 Liquid Peptides versus Numbuzin 9+ NAD Bio Lifting-Sil Essence. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging essence is formulated around Niacinamide and Adenosine to soften the look of wrinkles and refine skin texture. Water Glycerin Butylene Glycol Inulin Sodium Hyaluronate Panthenol Alpha-Glucan Oligosaccharide Carnosine Carbomer Polysorbate 20 Caprylyl Glycol Phenoxyethanol Hydroxypropyl Cyclodextrin Dunaliella Salina Extract Ethylhexylglycerin Citric Acid Palmitoyl Tripeptide-5 Sodium Benzoate Acetyl Hexapeptide-8 Tetrapeptide-21 Pentapeptide-18 Palmitoyl Tripeptide-1 Pantolactone Palmitoyl Tripeptide-38 Palmitoyl Tetrapeptide-7 Glyceryl Caprylate Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Phenylpropanol Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Potassium Sorbate Xanthan Gum Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum Hydrogenated Poly(C6-14 Olefin) Polyglycerin-3 Pentaerythrityl Tetraethylhexanoate Propanediol Dimethicone 1,2-Hexanediol Niacinamide Methylpropanediol Cetearyl Alcohol Glyceryl Stearate Hydrogenated Vegetable Oil Polyglyceryl-3 Methylglucose Distearate Butyrospermum Parkii Butter Dimethicone Crosspolymer Ammonium Acryloyldimethyltaurate/Vp Copolymer Sodium Polyacrylate Hydrogenated Lecithin Pentylene Glycol Tromethamine Adenosine Palmitic Acid Stearic Acid Sodium Phytate Cholesterol Adenosine Triphosphate Nicotinamide Adenine Dinucleotide Beta-Glucan Tocopherol Copper Gluconate Saccharomyces/Copper Ferment Saccharomyces/Iron Ferment Saccharomyces/Magnesium Ferment Saccharomyces/Silicon Ferment Saccharomyces/Zinc Ferment Capryloyl Dipeptide-17 Thioctic Acid Leuconostoc/Radish Root Ferment Filtrate Glutathione Tremella Fuciformis Extract Haematococcus Pluvialis Oil Potassium Hydroxide Resveratrol Hesperidin Methyl Chalcone Sorbitan Laurate Steareth-20 Astaxanthin Sodium Lactate Hydroxyethylcellulose Acetyl Dipeptide-1 Cetyl Ester Dipeptide Diaminobutyroyl Benzylamide Diacetate Heptasodium Hexacarboxymethyl Dipeptide-12 Sodium Citrate Chlorhexidine Digluconate Dextran Hexapeptide-2 Magnesium Chloride Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Acetyl Tetrapeptide-5 Dipeptide-2 Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Biotin Biotinoyl Tripeptide-1 Acetyl Tetrapeptide-3 Trifolium Pratense Flower Extract Tocopheryl Acetate Palmitoyl Tripeptide-8 Dipeptide-4 Hexapeptide-11 Tripeptide-3 Sh-Decapeptide-7 Sh-Octapeptide-4 Ascorbic Acid Polypeptide Hexapeptide-9 Oligopeptide-3 Palmitoyl Hexapeptide-12 Tripeptide-1 Palmitoyl Pentapeptide-4 Ubiquinone Copper Tripeptide-1 Caffeoyl Tripeptide-1 Caffeoyl Sh-Octapeptide-4 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Carnosine is a dipeptide made from two amino acids. This ingredient helps: Glycation is the process of sugars binding to and damaging proteins. Too much sugar in our skin can lead to damaged collagen, contributing to factors of aging. Carnosine is water-soluble and is not able to travel deeper layers of skin. This leads to some doubt about whether it can boost collagen in skin, since collagen is located in the deeper layers of skin. Fun fact: Carnosine can be naturally found in our muscles and brain. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other