Peptide Skincare & BeautySkin science and ingredient guides

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Medik8 Liquid Peptides Versus Sesderma Factor G Renew Serum

Medik8 Liquid Peptides Versus Sesderma Factor G Renew Serum Detailed comparison of Medik8 Liquid Peptides versus Sesderma Factor G Renew Serum. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and r

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Medik8 Liquid Peptides Versus Sesderma Factor G Renew Serum Detailed comparison of Medik8 Liquid Peptides versus Sesderma Factor G Renew Serum. This anti-aging serum is formulated around Carnosine and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 and Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 to soften the look of wrinkles and refine skin texture. Water Glycerin Butylene Glycol Inulin Sodium Hyaluronate Panthenol Alpha-Glucan Oligosaccharide Carnosine Carbomer Polysorbate 20 Caprylyl Glycol Phenoxyethanol Hydroxypropyl Cyclodextrin Dunaliella Salina Extract Ethylhexylglycerin Citric Acid Palmitoyl Tripeptide-5 Sodium Benzoate Acetyl Hexapeptide-8 Tetrapeptide-21 Pentapeptide-18 Palmitoyl Tripeptide-1 Pantolactone Palmitoyl Tripeptide-38 Palmitoyl Tetrapeptide-7 Glyceryl Caprylate Lactic Acid/Glycolic Acid Copolymer Polyvinyl Alcohol Phenylpropanol Copper Palmitoyl Heptapeptide-14 Heptapeptide-15 Palmitate Potassium Sorbate Xanthan Gum Water, Glycerin, Butylene Glycol, Inulin, Sodium Hyaluronate, Panthenol, Alpha-Glucan Oligosaccharide, Carnosine, Carbomer, Polysorbate 20, Caprylyl Glycol, Phenoxyethanol, Hydroxypropyl Cyclodextrin, Dunaliella Salina Extract, Ethylhexylglycerin, Citric Acid, Palmitoyl Tripeptide-5, Sodium Benzoate, Acetyl Hexapeptide-8, Tetrapeptide-21, Pentapeptide-18, Palmitoyl Tripeptide-1, Pantolactone, Palmitoyl Tripeptide-38, Palmitoyl Tetrapeptide-7, Glyceryl Caprylate, Lactic Acid/Glycolic Acid Copolymer, Polyvinyl Alcohol, Phenylpropanol, Copper Palmitoyl Heptapeptide-14, Heptapeptide-15 Palmitate, Potassium Sorbate, Xanthan Gum Bis-PEG-18 Methyl Ether Dimethyl Silane Propanediol Lecithin PEG-40 Hydrogenated Castor Oil Malus Domestica Fruit Cell Culture Extract Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76 Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2 Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1 Nicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40 Alcohol Caprooyl Tetrapeptide-3 Centella Asiatica Extract Dextran Dipotassium Phosphate Disodium EDTA Tocopheryl Acetate Ergothioneine Hydrochloric Acid Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2 Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6 Nicotiana Benthamiana Sh-Polypedtide-7 Parfum Potassium Phosphate Quercetin Resveratrol Dimethyl Ether Sodium Chloride Sodium Cholate Triethanolamine Tromethamine Water, Glycerin, Bis-PEG-18 Methyl Ether Dimethyl Silane, Propanediol, Lecithin, PEG-40 Hydrogenated Castor Oil, Malus Domestica Fruit Cell Culture Extract, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-76, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-2, Nicotiana Benthamiana Hexapeptide-40 Sh-Oligopeptide-1, Nicotiana Benthamiana Sh-Polypeptide-15 Hexapeptide-40, Alcohol, Caprooyl Tetrapeptide-3, Carbomer, Centella Asiatica Extract, Dextran, Dipotassium Phosphate, Disodium EDTA, Tocopheryl Acetate, Ergothioneine, Ethylhexylglycerin, Hydrochloric Acid, Nicotiana Benthamiana Octapeptide-30 Sh-Oligopeptide-2, Nicotiana Benthamiana Hexapeptide-40 Sh-Polypeptide-6, Nicotiana Benthamiana Sh-Polypedtide-7, Palmitoyl Tripeptide-5, Parfum, Phenoxyethanol, Polysorbate 20, Potassium Phosphate, Quercetin, Resveratrol Dimethyl Ether, Sodium Chloride, Sodium Cholate, Triethanolamine, Tromethamine, Xanthan Gum Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Palmitoyl Tripeptide-5 is a synthetic signal lipopeptide. This just means it is a three amino acid chain bolted onto a palmitic acid tail so it can slip through the skin's lipid barrier. This peptide has a "build more, lose less" approach. It's designed to mimic the collagen-stimulating activity in your skin by copying a snippet of one of your skin's own matrix proteins. This nudges fibroblasts into making more collagen while inhibiting the enzyme that breaks down skin protein. The manufacturer's in vivo study of 45 volunteers found 1% and 2.5% reduced the appearance of wrinkles by 7% and 12% respectively, after using it twice daily for 84 days. This is in the expected range for peptides; they're slow and cumulative actives and not overnight fixers. Typical