Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

MIAMO Multi-Peptide 20% Lifting Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum

MIAMO Multi-Peptide 20% Lifting Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Detailed comparison of MIAMO Multi-Peptide 20% Lifting Serum versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum. This anti-aging serum is formulated around Ace

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MIAMO Multi-Peptide 20% Lifting Serum Versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum Detailed comparison of MIAMO Multi-Peptide 20% Lifting Serum versus Peter Thomas Roth Peptide 21 Wrinkle Resist Serum. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Tripeptide-10 Citrulline and Acetyl Octapeptide-3 to soften the look of wrinkles. Water Glycerin Pentylene Glycol Chondrus Crispus Acetyl Hexapeptide-8 Pentapeptide-18 Acetyl Octapeptide-3 Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Butylene Glycol Hydroxyacetophenone Sodium Hyaluronate Glycol Carbomer Dipeptide Diaminobutyroyl Benzylamide Diacetate Polysorbate 20 Water, Glycerin, Pentylene Glycol, Chondrus Crispus, Acetyl Hexapeptide-8, Pentapeptide-18, Acetyl Octapeptide-3, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Butylene Glycol, Hydroxyacetophenone, Sodium Hyaluronate, Glycol, Carbomer, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Polysorbate 20 Rosa Centifolia Flower Water Isopropyl Myristate Squalane Mannitol Natto Gum Tripeptide-10 Citrulline Palmitoyl Hexapeptide-12 Acetyl Tetrapeptide-11 Acetyl Hexapeptide-1 Palmitoyl Oligopeptide Acetyl Tetrapeptide-9 Acetyl Tetrapeptide-2 Tripeptide-1 Hexapeptide-11 Palmitoyl Tripeptide-5 Trifluoroacetyl Tripeptide-2 Sodium Polyglutamate Tocopheryl Acetate Retinyl Palmitate Ascorbic Acid Hydrolyzed Soy Protein Hydrolyzed Wheat Protein Lecithin Pseudoalteromonas Ferment Extract Acrylates Copolymer Magnesium Chloride Dimethyl Isosorbide Acrylates/C10-30 Alkyl Acrylate Crosspolymer Leuconostoc/Radish Root Ferment Filtrate PEG-8 Dimethicone Disodium Phosphate Dextran Sodium Lactate Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Xanthan Gum Triethanolamine Sodium Phosphate Octyldodecanol Silica Sodium Propoxyhydroxypropyl Thiosulfate Silica Sodium Hydroxide Caprylyl Glycol Potassium Sorbate Sodium Benzoate Phenoxyethanol Water, Glycerin, Rosa Centifolia Flower Water, Isopropyl Myristate, Squalane, Mannitol, Butylene Glycol, Natto Gum, Tripeptide-10 Citrulline, Acetyl Octapeptide-3, Palmitoyl Hexapeptide-12, Acetyl Tetrapeptide-11, Acetyl Hexapeptide-8, Acetyl Hexapeptide-1, Palmitoyl Oligopeptide, Acetyl Tetrapeptide-9, Acetyl Tetrapeptide-2, Tripeptide-1, Palmitoyl Tetrapeptide-7, Hexapeptide-11, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Palmitoyl Tripeptide-5, Trifluoroacetyl Tripeptide-2, Palmitoyl Tripeptide-1, Sodium Polyglutamate, Sodium Hyaluronate, Tocopheryl Acetate, Retinyl Palmitate, Ascorbic Acid, Hydrolyzed Soy Protein, Hydrolyzed Wheat Protein, Lecithin, Pseudoalteromonas Ferment Extract, Acrylates Copolymer, Magnesium Chloride, Polysorbate 20, Dimethyl Isosorbide, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Leuconostoc/Radish Root Ferment Filtrate, PEG-8 Dimethicone, Disodium Phosphate, Carbomer, Dextran, Sodium Lactate, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Xanthan Gum, Triethanolamine, Sodium Phosphate, Octyldodecanol, Silica, Sodium Propoxyhydroxypropyl Thiosulfate Silica, Sodium Hydroxide, Caprylyl Glycol, Potassium Sorbate, Sodium Benzoate, Phenoxyethanol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Acetyl Octapeptide-3 is a synthetic peptide also commonly known as SNAP-8. It is a lab-made peptide often marketed as a gentler, topical alternative to Botox. It works by mimicking part of a protein involved in muscle contractions, which may help relax facial tension and reduce the appearance of fine lines (mostly around the eyes and forehead). It’s considered a “next-gen” version of Argireline (Acetyl Hexapeptide-8), an older peptide with more research behind it that also supports collagen production. SNAP-8 showed slightly better results than Argireline in one small manufacturer-funded study, but there’s limited independent research. Plus, most tests use concentrations higher than what’s typically found in skincare products. This ingredient might offer a subtle smoothing effect but it won't don’t deliver the dramatic results of actual Botox injections. Think of it more like a supporting actor in your skincare lineup. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrie