Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

NAELI 4.25% Retinoid Collagen Night Moisturizer Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

NAELI 4.25% Retinoid Collagen Night Moisturizer Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of NAELI 4.25% Retinoid Collagen Night Moisturizer versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This night moist

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NAELI 4.25% Retinoid Collagen Night Moisturizer Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of NAELI 4.25% Retinoid Collagen Night Moisturizer versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This night moisturizer is formulated around Aloe Barbadensis Leaf Juice and Thioctic Acid to hydrate skin. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. Water Aloe Barbadensis Leaf Juice Caprylic/Capric Triglyceride Propanediol C12-15 Alkyl Benzoate Cetearyl Alcohol Cetearyl Glucoside Isostearyl Palmitate Butyrospermum Parkii Butter Saccharide Isomerate Polyacrylamide C13-14 Isoparaffin Laureth-7 Mangifera Indica Seed Butter Ethoxydiglycol Glycerin Argania Spinosa Kernel Oil Allantoin Camellia Sinensis Extract Hyaluronic Acid Tocopheryl Acetate Thioctic Acid Sodium PCA Punica Granatum Extract Tetrahexyldecyl Ascorbate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Cymbopogon Schoenanthus Oil Phenoxyethanol Caprylyl Glycol Water, Aloe Barbadensis Leaf Juice, Caprylic/Capric Triglyceride, Propanediol, C12-15 Alkyl Benzoate, Cetearyl Alcohol, Cetearyl Glucoside, Isostearyl Palmitate, Butyrospermum Parkii Butter, Saccharide Isomerate, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Mangifera Indica Seed Butter, Ethoxydiglycol, Glycerin, Argania Spinosa Kernel Oil, Allantoin, Camellia Sinensis Extract, Hyaluronic Acid, Tocopheryl Acetate, Thioctic Acid, Sodium PCA, Punica Granatum Extract, Tetrahexyldecyl Ascorbate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cymbopogon Schoenanthus Oil, Phenoxyethanol, Caprylyl Glycol Dimethicone Tapioca Starch Dimethicone Crosspolymer Retinol Retinyl Propionate Niacinamide Palmitoyl Pentapeptide-4 DMDM Hydantoin Polysorbate 20 Laureth-4 Dimethiconol Polymethylsilsesquioxane Aminomethyl Propanol Titanium Dioxide Disodium EDTA Iodopropynyl Butylcarbamate Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. C13-14 Isoparaffin is a synthetic emollient, solvent, and thickening agent. It helps soften skin and improves spreadability without leaving a greasy residue. This ingredient has been found to be non-sensitizing and safe for use in cosmetics. Two things floating around online that cause fear-mongering: There's one scary-sounding study related to kidney tumors in male rats; this depends on a protein called alpha-2u-globulin that binds the ingredient and clogs up kidney cells. Female rats barely make this protein, and humans don't make it at all so this effect cannot happen to us. Regulatory bodies have states this rat-only pathway shouldn't be used to judge human risk. The other thing you'll see is 1,4-dioxane being a trace byproduct that can form during manufacturing of petroleum-derived ingredients. This is a real, but heavily managed/monitored issue. This byproduct is removed through purification steps before the ingredients goes into the formula. Regulatory bodies also actively monitor residual levels for safety. One last thing to note: this ingredient is a pure hydrocarbon with no fatty-acid or ester chains for Malassezia to feed on, so it's considered fungal acne safe. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actual