Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Multi-Peptide Advanced Serum Versus Medik8 Liquid Peptides Advanced MP

Naturium Multi-Peptide Advanced Serum Versus Medik8 Liquid Peptides Advanced MP Detailed comparison of Naturium Multi-Peptide Advanced Serum versus Medik8 Liquid Peptides Advanced MP. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic

This source-based comparison does not add ratings or recommend a winner.

Naturium Multi-Peptide Advanced Serum Versus Medik8 Liquid Peptides Advanced MP Detailed comparison of Naturium Multi-Peptide Advanced Serum versus Medik8 Liquid Peptides Advanced MP. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Ferulic Acid to soften the look of wrinkles. This anti-aging serum is formulated around Palmitoyl Tripeptide-38 and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. Water Propanediol Caprylic/Capric Triglyceride Isopentyldiol Ethylhexyl Polyhydroxystearate Squalane Tetradecane Glyceryl Stearate Citrate Butyrospermum Parkii Butter Polyglyceryl-3 Stearate Helianthus Annuus Extract Oryza Sativa Bran Extract Mannitol Phosphatidylcholine Ferulic Acid Arginine Acetyl Hexapeptide-8 Copper Palmitoyl Heptapeptide-14 Palmitoyl Sh-Heptapeptide-12 Sp Hydrolyzed Collagen Rosmarinus Officinalis Leaf Extract Lactic Acid/Glycolic Acid Copolymer Glycerin Tocopherol Pullulan Lysolecithin Sclerotium Gum Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Dimethicone Sodium Phytate Diglycerin Hydrogenated Lecithin Silica Cetyl Alcohol Hydroxyacetophenone Polysorbate 60 Sorbitan Isostearate Sodium Hydroxide Sodium Benzoate Potassium Sorbate Polyvinyl Alcohol Decyl Glucoside Xanthan Gum Tocopheryl Acetate Sodium Chloride Citric Acid Phenoxyethanol Water, Propanediol, Caprylic/Capric Triglyceride, Isopentyldiol, Ethylhexyl Polyhydroxystearate, Squalane, Tetradecane, Glyceryl Stearate Citrate, Butyrospermum Parkii Butter, Polyglyceryl-3 Stearate, Helianthus Annuus Extract, Oryza Sativa Bran Extract, Mannitol, Phosphatidylcholine, Ferulic Acid, Arginine, Acetyl Hexapeptide-8, Copper Palmitoyl Heptapeptide-14, Palmitoyl Sh-Heptapeptide-12 Sp, Hydrolyzed Collagen, Rosmarinus Officinalis Leaf Extract, Lactic Acid/Glycolic Acid Copolymer, Glycerin, Tocopherol, Pullulan, Lysolecithin, Sclerotium Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dimethicone, Sodium Phytate, Diglycerin, Hydrogenated Lecithin, Silica, Cetyl Alcohol, Hydroxyacetophenone, Polysorbate 60, Sorbitan Isostearate, Sodium Hydroxide, Sodium Benzoate, Potassium Sorbate, Polyvinyl Alcohol, Decyl Glucoside, Xanthan Gum, Tocopheryl Acetate, Sodium Chloride, Citric Acid, Phenoxyethanol Dimethyl Isosorbide Butylene Glycol Undecane Inulin Microcrystalline Cellulose Ceteareth-20 Tridecane Sodium Hyaluronate Palmitoyl Tripeptide-38 Panthenol Palmitoyl Tripeptide-5 Polyacrylate Crosspolymer-6 Palmitoyl Tripeptide-1 Tetrapeptide-21 Palmitoyl Tetrapeptide-10 Palmitoyl Tetrapeptide-7 Ammonium Polyacryloyldimethyl Taurate Glyceryl Linoleate Pentapeptide-18 Oligopeptide-1 Arginine/Lysine Polypeptide Sucrose Palmitate Cetyl Palmitate Ethylhexylglycerin Carbomer Heptapeptide-15 Palmitate Benzotriazolyl Dodecyl P-Cresol Polysorbate 80 Sorbitan Stearate Polysorbate 20 Carnosine Sodium Metabisulfite Dunaliella Salina Extract Helianthus Annuus Seed Oil Hydroxypropyl Cyclodextrin Dimethicone/Vinyl Dimethicone Crosspolymer Caprylyl Glycol Pantolactone Disodium EDTA T-Butyl Alcohol Glyceryl Caprylate Phenylpropanol Water, Glycerin, Dimethicone, Dimethyl Isosorbide, Butylene Glycol, Undecane, Arginine, Inulin, Microcrystalline Cellulose, Ceteareth-20, Tridecane, Tocopherol, Hydroxyacetophenone, Sodium Hyaluronate, Palmitoyl Tripeptide-38, Panthenol, Caprylic/Capric Triglyceride, Palmitoyl Tripeptide-5, Polyacrylate Crosspolymer-6, Palmitoyl Tripeptide-1, Pull These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Arginine is a semi-essential amino acid. This just means our bodies can product a bit on its own, but sometimes needs a little boost from food sources. It is a part of your skin's natural moisturizing factor (NMF), or the water-loving molecules in your outermost layer of skin (stratum corneum) that keeps everything hydrated and happy. Here's an interesting thing about Arginine: your skin converts it into urea through the Krebs-Henseleit urea cycle. Urea is one of the most effective humectants your skin naturally produces. A clinical study showed applying 2.5% arginine hydrochloride to atopic dermatitis skin showed significant urea levels in the stratum corneum and improved moisture in just four weeks. Arginine is also a precursor to nitric oxide; nitric oxide improves microcirculation and supports wound healing and collagen synthesis. One study found that an amino acid complex containing Arginine reduced skin irritation, improved hydration, and accelerated skin repair in clinical / in-vivo studies. Arginine itself is an amino acid and not a fatty acid, oil, or ester. On its own, it's not a direct food source for Malassezia, or the yeast that causes fungal acne. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores du