Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Multi-Peptide Eye Cream Versus Cetaphil Deep Hydration Refreshing Eye Serum

Naturium Multi-Peptide Eye Cream Versus Cetaphil Deep Hydration Refreshing Eye Serum Detailed comparison of Naturium Multi-Peptide Eye Cream versus Cetaphil Deep Hydration Refreshing Eye Serum. This anti-aging eye moisturizer is formulated around Acetyl Hexape

This source-based comparison does not add ratings or recommend a winner.

Naturium Multi-Peptide Eye Cream Versus Cetaphil Deep Hydration Refreshing Eye Serum Detailed comparison of Naturium Multi-Peptide Eye Cream versus Cetaphil Deep Hydration Refreshing Eye Serum. This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This calming eye moisturizer is formulated around 4-T-Butylcyclohexanol and Hydrolyzed Hyaluronic Acid to calm redness and hydrate skin. Water Glycerin Simmondsia Chinensis Seed Oil Stearic Acid Squalane Glyceryl Stearate Cetyl Alcohol Stearyl Alcohol Palmitic Acid Acetyl Hexapeptide-8 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Dunaliella Salina Extract Panthenol Sodium Hyaluronate Hydroxyacetophenone Sorbitan Oleate Aluminum Starch Octenylsuccinate Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Phenoxyethanol Butylene Glycol 1,2-Hexanediol Boron Nitride Caprylyl Glycol Tocopheryl Acetate Isohexadecane Chlorphenesin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Sodium Hydroxide Polysorbate 80 Carbomer Sodium Lactate Polysorbate 20 Citric Acid Ethylhexylglycerin Pantolactone Sodium Benzoate Potassium Sorbate Water, Glycerin, Simmondsia Chinensis Seed Oil, Stearic Acid, Squalane, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Palmitic Acid, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Dunaliella Salina Extract, Panthenol, Sodium Hyaluronate, Hydroxyacetophenone, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, Butylene Glycol, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Tocopheryl Acetate, Isohexadecane, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Polysorbate 80, Carbomer, Sodium Lactate, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Pantolactone, Sodium Benzoate, Potassium Sorbate Dicaprylyl Carbonate Polyglyceryl-6 Distearate Distarch Phosphate 4-T-Butylcyclohexanol Anhydroxylitol Bisabolol Caprylyl/Capryl Glucoside Globularia Alypum Leaf Extract Hydrolyzed Hyaluronic Acid Jojoba Esters Pentylene Glycol Polyglyceryl-3 Beeswax Polyisobutene Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Sodium PCA Tocopherol Xylitol Xylitylglucoside Water, Dicaprylyl Carbonate, Glycerin, 1,2-Hexanediol, Polyglyceryl-6 Distearate, Distarch Phosphate, 4-T-Butylcyclohexanol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Anhydroxylitol, Bisabolol, Caprylyl/Capryl Glucoside, Cetyl Alcohol, Citric Acid, Dunaliella Salina Extract, Ethylhexylglycerin, Globularia Alypum Leaf Extract, Hydrolyzed Hyaluronic Acid, Jojoba Esters, Palmitoyl Tripeptide-5, Panthenol, Pantolactone, Pentylene Glycol, Phenoxyethanol, Polyglyceryl-3 Beeswax, Polyisobutene, Potassium Sorbate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Sodium Benzoate, Sodium Hyaluronate, Sodium Hydroxide, Sodium PCA, Sorbitan Oleate, Tocopherol, Xylitol, Xylitylglucoside Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Cetyl Alcohol is a fatty alcohol. Fatty Alcohols are most often used as an emollient or to thicken a product. Its main roles are: Though it has "alcohol" in the name, it is not related to denatured alcohol or ethyl alcohol. The FDA allows products labeled "alcohol-free" to have fatty alcohols. This ingredient may not be fungal acne safe. It is a primary fatty alcohol with a chain length above 12 carbons. A study from 2019 show Malassezia can feed on fatty alcohols in this range, so it may trigger fungal acne in those prone to it. Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due to this, citric acid is usually included in small amounts as a pH adjuster. This helps keep products slightly more acidic and compatible with skin's natural pH. In skincare formulas, citric acid can: While it can provide some skin benefits, research shows lactic acid and glycolic acid are generally more effective and less irritating exfoliants. Most citric acid used in skincare today is made by fermenting sugars (usually from molasses). This synthetic version is identical to the natural citrus form but easier to stabilize and use in formulations. Rosacea skin has a lower threshold for acids generally, with 62.5% of rosacea subjects in one study reacting to lactic acid in a sting test. This is why we mark citric acid as a potential rosacea trigger. However, this ingredient shows up as a pH adjuster or chelator at roughly 0.1-1% in many products. These low levels are unlikely to be an issue for rosacea skin and becomes a potential trigger at exfoliating concentrations (20%). Because everybody's skin is unique, we recommend a patch test if you a