Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Multi-Peptide Eye Cream Versus Tiege Hanley AM/PM Eye Cream

Naturium Multi-Peptide Eye Cream Versus Tiege Hanley AM/PM Eye Cream Detailed comparison of Naturium Multi-Peptide Eye Cream versus Tiege Hanley AM/PM Eye Cream. This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapepti

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Naturium Multi-Peptide Eye Cream Versus Tiege Hanley AM/PM Eye Cream Detailed comparison of Naturium Multi-Peptide Eye Cream versus Tiege Hanley AM/PM Eye Cream. This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Niacinamide to soften the look of wrinkles and fade the look of dark spots. Water Glycerin Simmondsia Chinensis Seed Oil Stearic Acid Squalane Glyceryl Stearate Cetyl Alcohol Stearyl Alcohol Palmitic Acid Acetyl Hexapeptide-8 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Dunaliella Salina Extract Panthenol Sodium Hyaluronate Hydroxyacetophenone Sorbitan Oleate Aluminum Starch Octenylsuccinate Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Phenoxyethanol Butylene Glycol 1,2-Hexanediol Boron Nitride Caprylyl Glycol Tocopheryl Acetate Isohexadecane Chlorphenesin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Sodium Hydroxide Polysorbate 80 Carbomer Sodium Lactate Polysorbate 20 Citric Acid Ethylhexylglycerin Pantolactone Sodium Benzoate Potassium Sorbate Water, Glycerin, Simmondsia Chinensis Seed Oil, Stearic Acid, Squalane, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Palmitic Acid, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Dunaliella Salina Extract, Panthenol, Sodium Hyaluronate, Hydroxyacetophenone, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, Butylene Glycol, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Tocopheryl Acetate, Isohexadecane, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Polysorbate 80, Carbomer, Sodium Lactate, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Pantolactone, Sodium Benzoate, Potassium Sorbate Cyclopentasiloxane Dimethicone Crosspolymer Niacinamide Cetearyl Alcohol Polymethylsilsesquioxane Isopropyl Palmitate Caffeine Bis-PEG-12 Dimethicone Beeswax C32-36 Isoalkyl Stearate PEG-100 Stearate Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Glucoside Water, Cyclopentasiloxane, Dimethicone Crosspolymer, Glycerin, Potassium Sorbate, Acetyl Hexapeptide-8, Phenoxyethanol, Niacinamide, Cetearyl Alcohol, Polymethylsilsesquioxane, Isopropyl Palmitate, Caffeine, Bis-PEG-12 Dimethicone Beeswax, C32-36 Isoalkyl Stearate, Glyceryl Stearate, PEG-100 Stearate, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Polysorbate 80, Cetearyl Glucoside, Stearic Acid, Caprylyl Glycol, Tocopheryl Acetate Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive. Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture. This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototo