Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Multi-Peptide Eye Cream Versus Tula Skincare Instant De-Puff Eye Renewal Serum

Naturium Multi-Peptide Eye Cream Versus Tula Skincare Instant De-Puff Eye Renewal Serum Detailed comparison of Naturium Multi-Peptide Eye Cream versus Tula Skincare Instant De-Puff Eye Renewal Serum. This anti-aging eye moisturizer is formulated around Acetyl

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Naturium Multi-Peptide Eye Cream Versus Tula Skincare Instant De-Puff Eye Renewal Serum Detailed comparison of Naturium Multi-Peptide Eye Cream versus Tula Skincare Instant De-Puff Eye Renewal Serum. This anti-aging eye moisturizer is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles. This anti-aging eye moisturizer is formulated around Lactococcus Ferment Lysate and Acetyl Hexapeptide-8 to soften the look of wrinkles. Water Glycerin Simmondsia Chinensis Seed Oil Stearic Acid Squalane Glyceryl Stearate Cetyl Alcohol Stearyl Alcohol Palmitic Acid Acetyl Hexapeptide-8 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Palmitoyl Tripeptide-5 Dunaliella Salina Extract Panthenol Sodium Hyaluronate Hydroxyacetophenone Sorbitan Oleate Aluminum Starch Octenylsuccinate Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Phenoxyethanol Butylene Glycol 1,2-Hexanediol Boron Nitride Caprylyl Glycol Tocopheryl Acetate Isohexadecane Chlorphenesin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Sodium Hydroxide Polysorbate 80 Carbomer Sodium Lactate Polysorbate 20 Citric Acid Ethylhexylglycerin Pantolactone Sodium Benzoate Potassium Sorbate Water, Glycerin, Simmondsia Chinensis Seed Oil, Stearic Acid, Squalane, Glyceryl Stearate, Cetyl Alcohol, Stearyl Alcohol, Palmitic Acid, Acetyl Hexapeptide-8, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Dunaliella Salina Extract, Panthenol, Sodium Hyaluronate, Hydroxyacetophenone, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Phenoxyethanol, Butylene Glycol, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Tocopheryl Acetate, Isohexadecane, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Polysorbate 80, Carbomer, Sodium Lactate, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Pantolactone, Sodium Benzoate, Potassium Sorbate Caprylic/Capric Triglyceride Hydrogenated Ethylhexyl Olivate Cetearyl Alcohol Lactococcus Ferment Lysate Sodium Potassium Aluminum Silicate Carthamus Tinctorius Seed Oil Camelina Sativa Seed Oil Silybum Marianum Seed Oil Curcuma Longa Root Extract Citrus Aurantium Dulcis Peel Extract Albizia Julibrissin Bark Extract Avena Sativa Bran Extract Camellia Sinensis Leaf Extract Vaccinium Angustifolium Fruit Extract Cichorium Intybus Root Extract Algae Extract Bacillus Ferment Olus Oil Hydrogenated Olive Oil Unsaponifiables Lactic Acid Yogurt Powder Hydrolyzed Rice Protein Ascorbyl Palmitate Darutoside Ammonium Acryloyldimethyltaurate/Vp Copolymer Silica Xanthan Gum Inulin Sodium Chloride Sorbic Acid Hexylene Glycol Pentylene Glycol CI 77891 Water, Caprylic/Capric Triglyceride, Hydrogenated Ethylhexyl Olivate, Glycerin, Butylene Glycol, Cetearyl Alcohol, Lactococcus Ferment Lysate, Sodium Potassium Aluminum Silicate, Carthamus Tinctorius Seed Oil, Camelina Sativa Seed Oil, Silybum Marianum Seed Oil, Curcuma Longa Root Extract, Citrus Aurantium Dulcis Peel Extract, Albizia Julibrissin Bark Extract, Avena Sativa Bran Extract, Camellia Sinensis Leaf Extract, Vaccinium Angustifolium Fruit Extract, Cichorium Intybus Root Extract, Algae Extract, Bacillus Ferment, Olus Oil, Hydrogenated Olive Oil Unsaponifiables, Acetyl Hexapeptide-8, Lactic Acid, Yogurt Powder, Hydrolyzed Rice Protein, Tocopheryl Acetate, Ascorbyl Palmitate, Darutoside, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Silica, Xanthan Gum, Inulin, Acrylates/ Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Citric Acid is an alpha hydroxy acid (AHA) naturally found in citrus fruits like oranges, lemons, and limes. Like other AHAs, citric acid can exfoliate skin by breaking down the bonds that hold dead skin cells together. This helps reveal smoother and brighter skin underneath. However, this exfoliating effect only happens at high concentrations (20%) which can be hard to find in cosmetic products. Due