Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Multi-Peptide Moisturizer Versus Neutrogena Hydro Boost Gel Crème

Naturium Multi-Peptide Moisturizer Versus Neutrogena Hydro Boost Gel Crème Detailed comparison of Naturium Multi-Peptide Moisturizer versus Neutrogena Hydro Boost Gel Crème US. This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmito

This source-based comparison does not add ratings or recommend a winner.

Naturium Multi-Peptide Moisturizer Versus Neutrogena Hydro Boost Gel Crème Detailed comparison of Naturium Multi-Peptide Moisturizer versus Neutrogena Hydro Boost Gel Crème US. This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles. This barrier-repair moisturizer is formulated around Sodium Hyaluronate to strengthen the skin barrier and hydrate skin. Water Glycerin Dimethicone Simmondsia Chinensis Seed Oil Squalane Glyceryl Stearate Cetyl Alcohol Niacinamide Stearyl Alcohol Palmitoyl Tripeptide-5 Pantolactone Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Hydrolyzed Plukenetia Volubilis Seed Extract Dunaliella Salina Extract Sodium Hyaluronate 3-O-Ethyl Ascorbic Acid Panthenol Caryodendron Orinocense Seed Oil Honokiol Magnolol Palmitic Acid Sorbitan Oleate Aluminum Starch Octenylsuccinate Hydroxyacetophenone Stearic Acid Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Polyglyceryl-6 Laurate 1,2-Hexanediol Boron Nitride Caprylyl Glycol Polyglyceryl-10 Oleate Isohexadecane Butylene Glycol Chlorphenesin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tocopheryl Acetate Polysorbate 80 Sorbitan Palmitate Sodium Hydroxide Sodium Benzoate Carbomer Sodium Lactate Phenoxyethanol Polysorbate 20 Citric Acid Ethylhexylglycerin Potassium Sorbate Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Hydroxyacetophenone, Stearic Acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate Cetearyl Olivate Polyacrylamide Sorbitan Olivate Dimethicone/Vinyl Dimethicone Crosspolymer Synthetic Beeswax C13-14 Isoparaffin Dimethiconol Dimethicone Crosspolymer Laureth-7 C12-14 Pareth-12 Water, Dimethicone, Glycerin, Cetearyl Olivate, Polyacrylamide, Sorbitan Olivate, Phenoxyethanol, Dimethicone/Vinyl Dimethicone Crosspolymer, Synthetic Beeswax, C13-14 Isoparaffin, Dimethiconol, Dimethicone Crosspolymer, Chlorphenesin, Laureth-7, Carbomer, Sodium Hyaluronate, Ethylhexylglycerin, C12-14 Pareth-12, Sodium Hydroxide These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epid