Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Naturium Multi-Peptide Moisturizer Versus Vanicream Daily Facial Moisturizer

Naturium Multi-Peptide Moisturizer Versus Vanicream Daily Facial Moisturizer Detailed comparison of Naturium Multi-Peptide Moisturizer versus Vanicream Daily Facial Moisturizer. This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmit

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Naturium Multi-Peptide Moisturizer Versus Vanicream Daily Facial Moisturizer Detailed comparison of Naturium Multi-Peptide Moisturizer versus Vanicream Daily Facial Moisturizer. This anti-aging moisturizer is formulated around Palmitoyl Tripeptide-5 and Palmitoyl Tripeptide-1 to soften the look of wrinkles. This barrier-repair moisturizer is formulated around Squalane and Hyaluronic Acid to strengthen the skin barrier and hydrate skin. Water Glycerin Dimethicone Simmondsia Chinensis Seed Oil Squalane Glyceryl Stearate Cetyl Alcohol Niacinamide Stearyl Alcohol Palmitoyl Tripeptide-5 Pantolactone Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Hydrolyzed Plukenetia Volubilis Seed Extract Dunaliella Salina Extract Sodium Hyaluronate 3-O-Ethyl Ascorbic Acid Panthenol Caryodendron Orinocense Seed Oil Honokiol Magnolol Palmitic Acid Sorbitan Oleate Aluminum Starch Octenylsuccinate Hydroxyacetophenone Stearic Acid Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Polyglyceryl-6 Laurate 1,2-Hexanediol Boron Nitride Caprylyl Glycol Polyglyceryl-10 Oleate Isohexadecane Butylene Glycol Chlorphenesin Acrylates/C10-30 Alkyl Acrylate Crosspolymer Tocopheryl Acetate Polysorbate 80 Sorbitan Palmitate Sodium Hydroxide Sodium Benzoate Carbomer Sodium Lactate Phenoxyethanol Polysorbate 20 Citric Acid Ethylhexylglycerin Potassium Sorbate Water, Glycerin, Dimethicone, Simmondsia Chinensis Seed Oil, Squalane, Glyceryl Stearate, Cetyl Alcohol, Niacinamide, Stearyl Alcohol, Palmitoyl Tripeptide-5, Pantolactone, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Hydrolyzed Plukenetia Volubilis Seed Extract, Dunaliella Salina Extract, Sodium Hyaluronate, 3-O-Ethyl Ascorbic Acid, Panthenol, Caryodendron Orinocense Seed Oil, Honokiol, Magnolol, Palmitic Acid, Sorbitan Oleate, Aluminum Starch Octenylsuccinate, Hydroxyacetophenone, Stearic Acid, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Polyglyceryl-6 Laurate, 1,2-Hexanediol, Boron Nitride, Caprylyl Glycol, Polyglyceryl-10 Oleate, Isohexadecane, Butylene Glycol, Chlorphenesin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tocopheryl Acetate, Polysorbate 80, Sorbitan Palmitate, Sodium Hydroxide, Sodium Benzoate, Carbomer, Sodium Lactate, Phenoxyethanol, Polysorbate 20, Citric Acid, Ethylhexylglycerin, Potassium Sorbate Pentylene Glycol Polyglyceryl-2 Stearate Hyaluronic Acid Ceramide EOP Ceramide Ng Ceramide NP Ceramide As Ceramide AP Carnosine Hydrogenated Lecithin Phytosterols Polyacrylate Crosspolymer-11 Water, Squalane, Glycerin, Pentylene Glycol, Polyglyceryl-2 Stearate, Glyceryl Stearate, Stearyl Alcohol, Hyaluronic Acid, Ceramide EOP, Ceramide Ng, Ceramide NP, Ceramide As, Ceramide AP, Carnosine, Hydrogenated Lecithin, Phytosterols, Caprylyl Glycol, Polyacrylate Crosspolymer-11, 1,2-Hexanediol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Glyceryl Stearate is made by reacting glycerin with stearic acid (typically sourced from plant oils like palm or coconut). It's an emulsifier, emollient, and mild occlusive. Emulsifiers help ingredients like oil and water stay mixed so your formula stays nicely blended and uniform in texture. This ingredient is typically used in concentrations between 1-10%. Studies have found it to be non-sensitizing, non-phototoxic, and non-photoallergenic. A close cousin of this ingredient is Glyceryl Stearate SE ("self-emulsifying"). This just has a small amount of sodium or potassium stearate added so it can emulsify without a co-emulsifier. Since this ingredient is an ester of a C18 fatty acid, it may not be fungal acne safe. The Malassezia yeast can potentially metabolize within the C11-C24 range. Fun fact: The human body also creates Glyceryl Stearate naturally. Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum). It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores. This is due to how structurally similar it is to what your skin already produces. Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectan