Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Neogen Real Peptide Serum Versus Neogen Probiotics Double Action Serum

Neogen Real Peptide Serum Versus Neogen Probiotics Double Action Serum Detailed comparison of Neogen Real Peptide Serum versus Neogen Probiotics Double Action Serum. This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften th

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Neogen Real Peptide Serum Versus Neogen Probiotics Double Action Serum Detailed comparison of Neogen Real Peptide Serum versus Neogen Probiotics Double Action Serum. This anti-aging serum is formulated around Niacinamide and Palmitoyl Tripeptide-5 to soften the look of wrinkles and refine skin texture. This barrier-repair serum is formulated around Lactobacillus Ferment Lysate and Niacinamide to strengthen the skin barrier and calm redness. Water Dipropylene Glycol Propanediol Glycerin Niacinamide Caprylic/Capric Triglyceride 1,2-Hexanediol Hydroxyethyl Urea Diethoxyethyl Succinate Acrylates/C10-30 Alkyl Acrylate Crosspolymer Butylene Glycol Tromethamine Polyglyceryl-10 Laurate Inonotus Obliquus Extract Xanthan Gum Ethylhexylglycerin Adenosine Cyamopsis Tetragonoloba Gum Sodium Hyaluronate Agar Ubiquinone Tropaeolum Majus Flower/Leaf/Stem Extract Palmitoyl Tripeptide-5 Morinda Citrifolia Leaf Extract Morinda Citrifolia Flower Extract Coccinia Indica Fruit Extract Moringa Oleifera Seed Oil Solanum Melongena Fruit Extract Simmondsia Chinensis Seed Oil Curcuma Longa Root Extract Corallina Officinalis Extract Ocimum Sanctum Leaf Extract Acetyl Hexapeptide-8 Copper Tripeptide-1 Tripeptide-1 Tripeptide-29 Palmitoyl Tetrapeptide-7 Palmitoyl Tripeptide-1 Palmitoyl Pentapeptide-4 Hexapeptide-12 Hexapeptide-9 Tripeptide-2 Nonapeptide-1 Hexapeptide-11 Water, Dipropylene Glycol, Propanediol, Glycerin, Niacinamide, Caprylic/Capric Triglyceride, 1,2-Hexanediol, Hydroxyethyl Urea, Diethoxyethyl Succinate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Butylene Glycol, Tromethamine, Polyglyceryl-10 Laurate, Inonotus Obliquus Extract, Xanthan Gum, Ethylhexylglycerin, Adenosine, Cyamopsis Tetragonoloba Gum, Sodium Hyaluronate, Agar, Ubiquinone, Tropaeolum Majus Flower/Leaf/Stem Extract, Palmitoyl Tripeptide-5, Morinda Citrifolia Leaf Extract, Morinda Citrifolia Flower Extract, Coccinia Indica Fruit Extract, Moringa Oleifera Seed Oil, Solanum Melongena Fruit Extract, Simmondsia Chinensis Seed Oil, Curcuma Longa Root Extract, Corallina Officinalis Extract, Ocimum Sanctum Leaf Extract, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Tripeptide-29, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Hexapeptide-12, Hexapeptide-9, Tripeptide-2, Nonapeptide-1, Hexapeptide-11 Lactobacillus Ferment Lysate 21% Isopentyldiol Triethylhexanoin Betaine Allantoin Trehalose Panthenol Lavandula Angustifolia Oil Citrus Aurantium Bergamia Fruit Oil Citrus Aurantium Dulcis Peel Oil Aniba Rosaeodora Wood Oil Rosmarinus Officinalis Leaf Oil Eucalyptus Globulus Leaf Oil Bifida Ferment Lysate Xylitol Juglans Regia Seed Oil Lactic Acid Undaria Pinnatifida Extract Streptococcus Thermophilus Ferment Honey Extract Sodium PCA Sodium Lactate Glyceryl Caprylate Arginine Aspartic Acid PCA Phospholipids Gluconic Acid Ceramide NP Glycine Alanine Musa Sapientum Fruit Extract Tuber Melanosporum Extract Daucus Carota Sativa Root Extract Serine Valine Cholesterol Isoleucine Threonine Proline Tuber Magnatum Extract Phenylalanine Histidine Phellinus Linteus Extract Glutathione Hyaluronic Acid Beta-Glucan Phytosterols Hydrolyzed Hyaluronic Acid Limonene Linalool Cetyl Ethylhexanoate Coco-Caprylate/Caprate Carbomer Coptis Japonica Extract Dextrin Theobroma Cacao Extract Hydrolyzed Collagen Squalane Polydecene Olea Europaea Fruit Oil Adansonia Digitata Seed Oil Hydrogenated Lecithin Acacia Senegal Gum Royal Je These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. 1,2-Hexanediol is a synthetic liquid and another multi-functional powerhouse. It is a: Humectant, drawing moisture into the skin Emollient, helping to soften skin Solvent, dispersing and stabilizing formulas Preservative booster, enhancing the antimicrobial activity of other preservatives Acetyl Hexapeptide-8 (also known as Argireline) is a synthetic hexapeptide that is often called a "topical Botox alternative". It works by mimicking how Botox relaxes muscles; it interferes with the signaling process that tells your facial muscles to contract. This can help soften expression lines like forehead wrinkles or crow's feet over time. The comparison to Botox does have limits because the molecule is water-loving and relatively large. Acetyl Hexapeptide-8 has a hard time absorbing deeply enough through the skin's outer barrier to actually reach the muscles. So whether it truly works the way Botox does at a biological level is still up for debate, but early clinical outcomes are fairly encouraging. A 12 week human study of a multi-ingredient regimen containing this ingredient saw: While some studies have observed improvements in wrinkle appearance, it is important to note that more consistent results are seen in multi-ingredient formulations (vs just Acetyl Hexapeptide-8 alone). Some research studies also used higher concentrations (up to 10%) while this ingredient is usually found in concentrations up to 0.005% in leave-on formulations. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Adenosine is a purine nucleoside that your body already makes in every cell. In skincare, it acts mainly as a skin conditioning and anti-aging agent. The way it works is fairly well mapped out: Your skin has cells called fibroblasts that build collagen (the stuff that keeps skin firm and smooth). Adenosine basically flips a switch on these cells that tells them to get to work making more collagen and other proteins. These cells slow down on their own as skin ages, so Adenosine helps give them a little nudge to keep going. The clinical backing is pretty solid too. A blind, randomized, placebo-controlled trial of 126 women aged 45-65 tested a 0.1% cream twice daily and found real improvements in crow's feet and frown lines using a precise 3D skin-mapping technique; these changes showed up by week 3 and held at 2 months. A la