Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum versus Paula's Choice Resist Intensive Wrinkl

This source-based comparison does not add ratings or recommend a winner.

Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Neutrogena Ageless Intensives Anti-Wrinkle Deep Wrinkle Serum versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum. This anti-aging serum is formulated around Squalane and Retinol to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Cyclopentasiloxane Dipropylene Glycol Dimethicone Isononyl Isononanoate Adipic Acid/Diglycol Crosspolymer Dimethicone/PEG-10/15 Crosspolymer Dimethicone/Vinyl Dimethicone Crosspolymer Squalane Glycerin Bisabolol Ethylhexylglycerin Sodium Chloride Caprylic/Capric Triglyceride Sodium Citrate Erythorbic Acid Dipotassium Glycyrrhizate BHT Retinol Tocopherol Avena Sativa Kernel Extract Water, Cyclopentasiloxane, Dipropylene Glycol, Dimethicone, Isononyl Isononanoate, Adipic Acid/Diglycol Crosspolymer, Dimethicone/PEG-10/15 Crosspolymer, Dimethicone/Vinyl Dimethicone Crosspolymer, Squalane, Glycerin, Bisabolol, Ethylhexylglycerin, Sodium Chloride, Caprylic/Capric Triglyceride, Sodium Citrate, Erythorbic Acid, Dipotassium Glycyrrhizate, BHT, Retinol, Tocopherol, Avena Sativa Kernel Extract Dimethiconol Neopentyl Glycol Diheptanoate Dicaprylyl Carbonate Phenyl Trimethicone Tetrahexyldecyl Ascorbate Tocotrienols Lecithin Laminaria Ochroleuca Extract Elaeis Guineensis Oil Stearyl Glycyrrhetinate Hexylene Glycol Caprylyl Glycol Phenoxyethanol Cyclopentasiloxane, Dimethiconol, Neopentyl Glycol Diheptanoate, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Squalane, Bisabolol, Tetrahexyldecyl Ascorbate, Retinol, Tocotrienols, Tocopherol, Lecithin, Laminaria Ochroleuca Extract, Avena Sativa Kernel Extract, Elaeis Guineensis Oil, Stearyl Glycyrrhetinate, Hexylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too. This ingredient helps sooth, hydrate, and protect the skin. The starches in colloidal oatmeal are able to bind water, keeping the skin hydrated. The cellulose and fiber in colloidal oatmeal help reduce inflammation. This can also help the skin feel softer. Colloidal Oatmeal is also an antioxidant. Antioxidants protect our skin from free-radical damage. Oatmeal also contains beneficial compounds: This ingredient is created by mixing grounded oatmeal and a liquid base. Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient. It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation. A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin. In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum. You'll likely see use concentrations quite low, usually 0.1-0.2%. Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in