Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Niod Copper Amino Isolate Lipid 1% (CAIL) Versus Biossance Squalane + Copper Peptide Rapid Plumping Serum

Niod Copper Amino Isolate Lipid 1% (CAIL) Versus Biossance Squalane + Copper Peptide Rapid Plumping Serum Detailed comparison of Niod Copper Amino Isolate Lipid 1% (CAIL) versus Biossance Squalane + Copper Peptide Rapid Plumping Serum Original. This barrier-re

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Niod Copper Amino Isolate Lipid 1% (CAIL) Versus Biossance Squalane + Copper Peptide Rapid Plumping Serum Detailed comparison of Niod Copper Amino Isolate Lipid 1% (CAIL) versus Biossance Squalane + Copper Peptide Rapid Plumping Serum Original. This barrier-repair serum is formulated around Bisabolol to strengthen the skin barrier. This hydrating serum is formulated around Squalane and Sodium Hyaluronate to hydrate skin and soften the look of wrinkles. Squalane Caprylic/Capric Triglyceride Glycerin Water Hydrogenated Starch Hydrolysate Sucrose Laurate Propanediol Sucrose Stearate Copper Tripeptide-1 Palmitamide Glycolipids Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran Vetiveria Zizanoides Root Extract Aphanizomenon Flos-Aquae Extract Hydroxymethoxyphenyl Decanone Bisabolol Biosaccharide Gum-1 Maltodextrin Potassium Sorbate Sodium Benzoate Chlorphenesin Phenoxyethanol Squalane, Caprylic/Capric Triglyceride, Glycerin, Water, Hydrogenated Starch Hydrolysate, Sucrose Laurate, Propanediol, Sucrose Stearate, Copper Tripeptide-1 Palmitamide, Glycolipids, Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran, Vetiveria Zizanoides Root Extract, Aphanizomenon Flos-Aquae Extract, Hydroxymethoxyphenyl Decanone, Bisabolol, Biosaccharide Gum-1, Maltodextrin, Potassium Sorbate, Sodium Benzoate, Chlorphenesin, Phenoxyethanol Sodium Hyaluronate Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Copper Tripeptide-1 Acmella Oleracea Extract Ectoin Tetrapeptide-30 Palmitoyl Hexapeptide-52 Copper PCA Panthenol Sodium Polyglutamate Camellia Sinensis Leaf Extract Aloe Barbadensis Flower Extract Passiflora Incarnata Flower Extract Melia Azadirachta Leaf Extract Solanum Melongena Fruit Extract Curcuma Longa Root Extract Ocimum Basilicum Flower/Leaf Extract Coccinia Indica Fruit Extract Melia Azadirachta Flower Extract Ocimum Sanctum Leaf Extract Corallina Officinalis Extract Polyacrylate Crosspolymer-6 Acacia Senegal Gum Xanthan Gum Ethylhexylglycerin Citric Acid Caprylyl Glycol Water, Glycerin, Propanediol, Squalane, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Copper Tripeptide-1, Acmella Oleracea Extract, Ectoin, Tetrapeptide-30, Palmitoyl Hexapeptide-52, Copper PCA, Panthenol, Sodium Polyglutamate, Camellia Sinensis Leaf Extract, Aloe Barbadensis Flower Extract, Passiflora Incarnata Flower Extract, Melia Azadirachta Leaf Extract, Solanum Melongena Fruit Extract, Curcuma Longa Root Extract, Ocimum Basilicum Flower/Leaf Extract, Coccinia Indica Fruit Extract, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Polyacrylate Crosspolymer-6, Acacia Senegal Gum, Xanthan Gum, Phenoxyethanol, Ethylhexylglycerin, Citric Acid, Caprylyl Glycol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Propanediol is an all-star ingredient. It softens, hydrates, and smooths the skin. It’s often used to: Propanediol is not likely to cause sensitivity and considered safe to use. It is derived from corn or petroleum with a clear color and no scent. Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum). It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores. This is due to how structurally similar it is to what your skin already produce