Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) Versus Niod Copper Amino Isolate Lipid 1% (CAIL)

Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) Versus Niod Copper Amino Isolate Lipid 1% (CAIL) Detailed comparison of Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) versus Niod Copper Amino Isolate Lipid 1% (CAIL). This anti-aging serum is formulated around Tripeptide-29 and Tripeptide-1 to soften the look of wrinkles. This barrier-repair serum is formulated around Bisabolol to strengthen the skin barrier. Water Glycerin Tripeptide-29 Bis(Tripeptide-1) Copper Acetate Tripeptide-1 Myristoyl Nonapeptide-3 Trifluoroacetyl Tripeptide-2 Acetyl Tetrapeptide-2 Sodium Hyaluronate Crosspolymer Glycogen Propanediol Pentylene Glycol Dextran Dimethyl Isosorbide Ethoxydiglycol Isoceteth-20 Leuconostoc/Radish Root Ferment Filtrate Caprylyl Glycol Ethylhexylglycerin Phenoxyethanol Chlorphenesin Water, Glycerin, Tripeptide-29, Bis(Tripeptide-1) Copper Acetate, Tripeptide-1, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin Squalane Caprylic/Capric Triglyceride Hydrogenated Starch Hydrolysate Sucrose Laurate Sucrose Stearate Copper Tripeptide-1 Palmitamide Glycolipids Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran Vetiveria Zizanoides Root Extract Aphanizomenon Flos-Aquae Extract Hydroxymethoxyphenyl Decanone Bisabolol Biosaccharide Gum-1 Maltodextrin Potassium Sorbate Sodium Benzoate Squalane, Caprylic/Capric Triglyceride, Glycerin, Water, Hydrogenated Starch Hydrolysate, Sucrose Laurate, Propanediol, Sucrose Stearate, Copper Tripeptide-1 Palmitamide, Glycolipids, Hydroxymethoxyphenyl Propylmethylmethoxybenzofuran, Vetiveria Zizanoides Root Extract, Aphanizomenon Flos-Aquae Extract, Hydroxymethoxyphenyl Decanone, Bisabolol, Biosaccharide Gum-1, Maltodextrin, Potassium Sorbate, Sodium Benzoate, Chlorphenesin, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Chlorphenesin is a synthetic preservative. It helps protect a product against bacteria in order to extend shelf life. In most cases, Chlorphenesin is paired with other preservatives such as phenoxyethanol and caprylyl glycol. Chlorphenesin is a biocide. This means it is able to help fight the microorganisms on our skin. It is also able to fight odor-releasing bacteria. Chlorphenesin is soluble in both water and glycerin. Studies show Chlorphenesin is easily absorbed by our skin. You should speak with a skincare professional if you have concerns about using Chlorphenesin. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon