Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) Versus Theramid Azid 15% Azelaic Acid Treatment

Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) Versus Theramid Azid 15% Azelaic Acid Treatment Detailed comparison of Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) versus Theramid Azid 15% Azelaic Acid Treatment. This anti-aging serum is formulated around Tripe

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Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) Versus Theramid Azid 15% Azelaic Acid Treatment Detailed comparison of Niod Copper Amino Isolate Serum 3 1:1 (CAIS3) versus Theramid Azid 15% Azelaic Acid Treatment. This anti-aging serum is formulated around Tripeptide-29 and Tripeptide-1 to soften the look of wrinkles. This calming serum is formulated around Azelaic Acid and Avena Sativa Kernel Flour to calm redness and clear breakouts. Water Glycerin Tripeptide-29 Bis(Tripeptide-1) Copper Acetate Tripeptide-1 Myristoyl Nonapeptide-3 Trifluoroacetyl Tripeptide-2 Acetyl Tetrapeptide-2 Sodium Hyaluronate Crosspolymer Glycogen Propanediol Pentylene Glycol Dextran Dimethyl Isosorbide Ethoxydiglycol Isoceteth-20 Leuconostoc/Radish Root Ferment Filtrate Caprylyl Glycol Ethylhexylglycerin Phenoxyethanol Chlorphenesin Water, Glycerin, Tripeptide-29, Bis(Tripeptide-1) Copper Acetate, Tripeptide-1, Myristoyl Nonapeptide-3, Trifluoroacetyl Tripeptide-2, Acetyl Tetrapeptide-2, Sodium Hyaluronate Crosspolymer, Glycogen, Propanediol, Pentylene Glycol, Dextran, Dimethyl Isosorbide, Ethoxydiglycol, Isoceteth-20, Leuconostoc/Radish Root Ferment Filtrate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin Azelaic Acid 15% Glycereth-26 Avena Sativa Kernel Flour Carnosine Ceramide NP Ceramide EOP Ceramide Ns Ceramide As Ceramide AP Gallyl Glucoside Propyl Gallate Epigallocatechin Gallatyl Glucoside Daucus Carota Sativa Root Cell Culture Lysate Gossypium Herbaceum Callus Culture Sphingomonas Ferment Extract Hydrogenated Lecithin Sucrose Distearate Glyceryl Stearate Dipropylene Glycol Dehydroacetic Acid Triethanolamine Benzyl Alcohol Citric Acid Water, Azelaic Acid 15%, Glycerin, Propanediol, Glycereth-26, Avena Sativa Kernel Flour, Carnosine, Acetyl Tetrapeptide-2, Ceramide NP, Ceramide EOP, Ceramide Ns, Ceramide As, Ceramide AP, Gallyl Glucoside, Propyl Gallate, Epigallocatechin Gallatyl Glucoside, Daucus Carota Sativa Root Cell Culture Lysate, Gossypium Herbaceum Callus Culture, Sphingomonas Ferment Extract, Ethylhexylglycerin, Hydrogenated Lecithin, Sucrose Distearate, Glyceryl Stearate, Dipropylene Glycol, Dehydroacetic Acid, Caprylyl Glycol, Phenoxyethanol, Triethanolamine, Benzyl Alcohol, Citric Acid These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This peptide is more commonly known as Thymulen 4 BG. It is derived from a youth hormone called thymopoietin. Thymopoietin helps regulate the immune system and decreases naturally with age. According to the manufacturer, this peptide boosts the skin's immune defenses and regenerates the outer layers of skin. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use co