Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Numbuzin No.5 Goodbye Blemish Serum Versus Paula's Choice 1% Retinol Treatment

Numbuzin No.5 Goodbye Blemish Serum Versus Paula's Choice 1% Retinol Treatment Detailed comparison of Numbuzin No.5 Goodbye Blemish Serum versus Paula's Choice 1% Retinol Treatment US. This brightening serum is formulated around Niacinamide and 3-O-Ethyl Ascor

This source-based comparison does not add ratings or recommend a winner.

Numbuzin No.5 Goodbye Blemish Serum Versus Paula's Choice 1% Retinol Treatment Detailed comparison of Numbuzin No.5 Goodbye Blemish Serum versus Paula's Choice 1% Retinol Treatment US. This brightening serum is formulated around Niacinamide and 3-O-Ethyl Ascorbic Acid to fade the look of dark spots and brighten dull-looking skin. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Hippophae Rhamnoides Extract Butylene Glycol Methyl Gluceth-20 Dipropylene Glycol Glycerin 1,2-Hexanediol Niacinamide Melia Azadirachta Flower Extract Ocimum Sanctum Leaf Extract Melia Azadirachta Leaf Extract Curcuma Longa Root Extract Corallina Officinalis Extract Citrus Limon Peel Oil Citrus Aurantium Dulcis Peel Oil Citrus Aurantifolia Oil Polygonum Cuspidatum Root Extract Scutellaria Baicalensis Root Extract Camellia Sinensis Leaf Extract Glycyrrhiza Glabra Root Extract Chamomilla Recutita Flower Extract Rosmarinus Officinalis Leaf Extract Centella Asiatica Extract Ascorbyl Glucoside Ascorbic Acid 3-O-Ethyl Ascorbic Acid Panthenol Sodium Hyaluronate Dipotassium Glycyrrhizate Glycereth-26 Ammonium Acryloyldimethyltaurate/Vp Copolymer Polyglyceryl-10 Laurate Carbomer Allantoin Tromethamine Water Hydrolyzed Jojoba Esters Disodium EDTA Citral Limonene Hippophae Rhamnoides Extract, Butylene Glycol, Methyl Gluceth-20, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Melia Azadirachta Leaf Extract, Curcuma Longa Root Extract, Corallina Officinalis Extract, Citrus Limon Peel Oil, Citrus Aurantium Dulcis Peel Oil, Citrus Aurantifolia Oil, Polygonum Cuspidatum Root Extract, Scutellaria Baicalensis Root Extract, Camellia Sinensis Leaf Extract, Glycyrrhiza Glabra Root Extract, Chamomilla Recutita Flower Extract, Rosmarinus Officinalis Leaf Extract, Centella Asiatica Extract, Ascorbyl Glucoside, Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Panthenol, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycereth-26, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Polyglyceryl-10 Laurate, Carbomer, Allantoin, Tromethamine, Water, Hydrolyzed Jojoba Esters, Disodium EDTA, Citral, Limonene Dimethicone Isononyl Isononanoate Castor Isostearate Succinate Glyceryl Stearate C12-15 Alkyl Benzoate Dimethicone Crosspolymer PEG-33 Polysorbate 20 Behenyl Alcohol PEG-100 Stearate Pentaerythrityl Tetraisostearate Polymethylsilsesquioxane Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Avena Sativa Kernel Extract Arctium Lappa Seed Oil Salix Alba Extract Glycine Soja Sterols Lecithin Tocopheryl Acetate Hydrolyzed Soy Protein Sorbitan Laurate Acetyl Dipeptide-1 Cetyl Ester Hydroxyethylcellulose Palmitoyl Tripeptide-1 Sodium Hydroxide Tribehenin Caprylyl Glycol Ethylhexylglycerin Pentylene Glycol PEG-75 Shea Butter Glycerides PPG-12/Smdi Copolymer PEG-10 Phytosterol PEG-8 Dimethicone PEG-14 Magnesium Aluminum Silicate Arachidyl Glucoside Arachidyl Alcohol Sclerotium Gum Phenoxyethanol Benzoic Acid Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hex These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics. Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity. Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation. It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh. Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated. This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%. Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating. Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Carbomer is a synthetic thickening and gelling agent. It's basically the ingredient that gives a lot of serums, gels, creams, and sunscreens their smooth, non-sticky texture. Although legally permitted at very high levels, carbomers are normally used at concentrations below 1%. It also needs to be neutralized to actually thicken, and because it is a large molecule, it doesn't really penetrate the skin barrier. Allergy-wise, the risk is very low. Clinical studies show carbomers have low potential for skin irritation/sensitization even at concentrations up to 100%. A 2024 UK study patch-tested 1,302 patients and found true allergy to the parent group of carbomer to be rare with no confirmed relevant reactions. Dipotassium Glycyrrhizate comes from licorice root. Extracts of licorice have demonstrated to have antibacterial, anti‐inflammatory, antiviral, antioxidant properties. One component, glabridin, has extra potent antioxidant and soothing properties. It has also been found to block pigmentation from UVB rays in guinea pigs. Licorice Root also contains a flavonoid. Flavonoids are a natural substance from in plants. Flavonoids also have antioxidant properties. Another component, glycyrrhizin, has been found to have anti-inflammatory and antimicrobial benefits. This may make licorice root extract effective at treating acne. Howe