Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Obagi Elastiderm Eye Cream Versus SkinMedica TNS® Advanced+ Serum

Obagi Elastiderm Eye Cream Versus SkinMedica TNS® Advanced+ Serum Detailed comparison of Obagi Elastiderm Eye Cream versus SkinMedica TNS® Advanced+ Serum. Water C12-15 Alkyl Benzoate Ethylhexyl Palmitate C13-15 Alkane Cyclopentasiloxane Glycerin Glyceryl Stea

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Obagi Elastiderm Eye Cream Versus SkinMedica TNS® Advanced+ Serum Detailed comparison of Obagi Elastiderm Eye Cream versus SkinMedica TNS® Advanced+ Serum. Water C12-15 Alkyl Benzoate Ethylhexyl Palmitate C13-15 Alkane Cyclopentasiloxane Glycerin Glyceryl Stearate PEG-100 Stearate Propylene Glycol Stearyl Alcohol Dipropylene Glycol Dibenzoate Dimethicone PPG-15 Stearyl Ether Benzoate Polyacrylamide Cetyl Alcohol Cetyl Dimethicone C13-14 Isoparaffin Xanthan Gum Magnesium Aluminum Silicate Laureth-7 Tocopheryl Acetate Glycyrrhiza Glabra Root Extract Algae Extract Vaccinium Angustifolium Fruit Extract Phenoxyethanol Methylparaben Ethylparaben Butylparaben Propylparaben Isobutylparaben Hdi/Trimethylol Hexyllactone Crosspolymer Sodium Hydroxide Malonic Acid Malachite Zinc Carbonate Silica Talc Alumina Mica CI 77891 CI 77491 CI 42090 Water, C12-15 Alkyl Benzoate, Ethylhexyl Palmitate, C13-15 Alkane, Cyclopentasiloxane, Glycerin, Glyceryl Stearate, PEG-100 Stearate, Propylene Glycol, Stearyl Alcohol, Dipropylene Glycol Dibenzoate, Dimethicone, PPG-15 Stearyl Ether Benzoate, Polyacrylamide, Cetyl Alcohol, Cetyl Dimethicone, C13-14 Isoparaffin, Xanthan Gum, Magnesium Aluminum Silicate, Laureth-7, Tocopheryl Acetate, Glycyrrhiza Glabra Root Extract, Algae Extract, Vaccinium Angustifolium Fruit Extract, Phenoxyethanol, Methylparaben, Ethylparaben, Butylparaben, Propylparaben, Isobutylparaben, Hdi/Trimethylol Hexyllactone Crosspolymer, Sodium Hydroxide, Malonic Acid, Malachite, Zinc Carbonate, Silica, Talc, Alumina, Mica, CI 77891, CI 77491, CI 42090 Pentylene Glycol Human Neonatal Fibroblast Conditioned Media Glycereth-7 Triacetate Shea Butter Ethyl Esters Ethoxydiglycol Lactococcus Ferment Lysate Whey Protein Chlorella Vulgaris Extract Saccharide Isomerate Dimer Tripeptide-43 Vitis Vinifera Flower Cell Extract Pyrus Malus Fruit Extract Hydroxyacetophenone Propanediol Polyacrylate Crosspolymer-6 Polyacrylate-13 Polyisobutene Sclerotium Gum PEG-12 Dimethicone Lecithin Pullulan Butylene Glycol Sodium Citrate Polysorbate 20 Aminomethyl Propanol Disodium EDTA Ethylhexylglycerin Water, Pentylene Glycol, Human Neonatal Fibroblast Conditioned Media, Glycereth-7 Triacetate, Shea Butter Ethyl Esters, Glycerin, Ethoxydiglycol, Lactococcus Ferment Lysate, Whey Protein, Chlorella Vulgaris Extract, Saccharide Isomerate, Dimer Tripeptide-43, Vitis Vinifera Flower Cell Extract, Pyrus Malus Fruit Extract, Hydroxyacetophenone, Tocopheryl Acetate, Propanediol, Xanthan Gum, Polyacrylate Crosspolymer-6, Polyacrylate-13, Polyisobutene, Sclerotium Gum, PEG-12 Dimethicone, Lecithin, Pullulan, Butylene Glycol, Sodium Citrate, Polysorbate 20, Aminomethyl Propanol, Disodium EDTA, Phenoxyethanol, Ethylhexylglycerin Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingredient is a rare sensitizer and allergic reactions are uncommon. Tocopheryl Acetate is a stable, shelf-friendly form of vitamin E. Formulators love it because plain vitamin E oxidizes quickly once it hits air. This acetate version stays stable and resists going off, helping to extend a product's shelf life. It's actually inactive on its own and works like a slow-release "storage" form; the enzymes in your skin called esterases gradually convert it into active vitamin E over time. One in vivo study showed 5% of the acetate in the living layer of the epidermis converted to vitamin E after 5 days of application. This study also found th