Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Obagi Retinol 1.0 Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum

Obagi Retinol 1.0 Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Obagi Retinol 1.0 versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum. This anti-aging treatment is formulated around Retinol to soften

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Obagi Retinol 1.0 Versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum Detailed comparison of Obagi Retinol 1.0 versus Paula's Choice Resist Intensive Wrinkle-Repair Retinol Serum. This anti-aging treatment is formulated around Retinol to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Caprylic/Capric Triglyceride Glyceryl Stearate Cyclopentasiloxane Butylene Glycol Stearic Acid Butyrospermum Parkii Butter Polysorbate 60 Stearyl Alcohol Glycerin Allyl Methacrylates Crosspolymer Retinol Polysorbate 20 Dimethicone Simmondsia Chinensis Seed Oil Chamomilla Recutita Flower Extract Hypericum Perforatum Flower Extract Malva Sylvestris Flower Extract Salvia Officinalis Leaf Extract Sambucus Nigra Flower Extract Cyclohexasiloxane Sorbitol Tocopheryl Acetate Ascorbic Acid Ubiquinone Sodium Hyaluronate Propylene Glycol BHT Bisabolol Dimethicone/Vinyl Dimethicone Crosspolymer Dipotassium Glycyrrhizate Disodium EDTA Triethanolamine Carbomer Glyceryl Acrylate/Acrylic Acid Copolymer Caprylyl Glycol Ethylhexylglycerin Hexylene Glycol Phenoxyethanol Water, Caprylic/Capric Triglyceride, Glyceryl Stearate, Cyclopentasiloxane, Butylene Glycol, Stearic Acid, Butyrospermum Parkii Butter, Polysorbate 60, Stearyl Alcohol, Glycerin, Allyl Methacrylates Crosspolymer, Retinol, Polysorbate 20, Dimethicone, Simmondsia Chinensis Seed Oil, Chamomilla Recutita Flower Extract, Hypericum Perforatum Flower Extract, Malva Sylvestris Flower Extract, Salvia Officinalis Leaf Extract, Sambucus Nigra Flower Extract, Cyclohexasiloxane, Sorbitol, Tocopheryl Acetate, Ascorbic Acid, Ubiquinone, Sodium Hyaluronate, Propylene Glycol, BHT, Bisabolol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dipotassium Glycyrrhizate, Disodium EDTA, Triethanolamine, Carbomer, Glyceryl Acrylate/Acrylic Acid Copolymer, Caprylyl Glycol, Ethylhexylglycerin, Hexylene Glycol, Phenoxyethanol Dimethiconol Neopentyl Glycol Diheptanoate Dicaprylyl Carbonate Phenyl Trimethicone Squalane Tetrahexyldecyl Ascorbate Tocotrienols Tocopherol Lecithin Laminaria Ochroleuca Extract Avena Sativa Kernel Extract Elaeis Guineensis Oil Stearyl Glycyrrhetinate Cyclopentasiloxane, Dimethiconol, Neopentyl Glycol Diheptanoate, Dicaprylyl Carbonate, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Squalane, Bisabolol, Tetrahexyldecyl Ascorbate, Retinol, Tocotrienols, Tocopherol, Lecithin, Laminaria Ochroleuca Extract, Avena Sativa Kernel Extract, Elaeis Guineensis Oil, Stearyl Glycyrrhetinate, Hexylene Glycol, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Bisabolol is a gentle skin conditioner, antioxidant, and soothing ingredient. It's primary claim to fame is soothing and research shows topically applied bisabolol can quiet the chemical messengers that cause your skin to become inflamed, helping to sooth any irritation. A clinical study found that applying 0.5% bisabolol daily for 8 weeks produced an average 9% decrease in skin pigmentation. Researchers found it can also suppress the process that leads to excess melanin production in skin. In vitro studies found that bisabolol combined with propylene glycol significantly increased skin permeability by increasing lipid fluidity in the stratum corneum. You'll likely see use concentrations quite low, usually 0.1-0.2%. Overall, this is a well-tolerated ingredient that works well in formulas designed for sensitive, reactive, or post-procedure skin. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy. Since D5 is volatile, it does its thing and then evaporates off the skin quickly. The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded