Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Olay Regenerist Retinol 24 Night Facial Serum Versus Paula's Choice Resist Intensive Repair Cream

Olay Regenerist Retinol 24 Night Facial Serum Versus Paula's Choice Resist Intensive Repair Cream Detailed comparison of Olay Regenerist Retinol 24 Night Facial Serum versus Paula's Choice Resist Intensive Repair Cream. This anti-aging serum is formulated arou

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Olay Regenerist Retinol 24 Night Facial Serum Versus Paula's Choice Resist Intensive Repair Cream Detailed comparison of Olay Regenerist Retinol 24 Night Facial Serum versus Paula's Choice Resist Intensive Repair Cream. This anti-aging serum is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This anti-aging moisturizer is formulated around Retinol and Simmondsia Chinensis Seed Oil to soften the look of wrinkles and hydrate skin. Water Dimethicone Glycerin Retinol Retinyl Propionate Niacinamide Palmitoyl Pentapeptide-4 Dimethiconol C13-14 Isoparaffin Laureth-4 Polysorbate 20 Laureth-7 Disodium EDTA Dimethicone Crosspolymer Polyacrylamide Titanium Dioxide Mica DMDM Hydantoin Iodopropynyl Butylcarbamate Water, Dimethicone, Glycerin, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Dimethiconol, C13-14 Isoparaffin, Laureth-4, Polysorbate 20, Laureth-7, Disodium EDTA, Dimethicone Crosspolymer, Polyacrylamide, Titanium Dioxide, Mica, DMDM Hydantoin, Iodopropynyl Butylcarbamate Ethylhexyl Stearate Simmondsia Chinensis Seed Oil Butylene Glycol Caprylic/Capric Triglyceride Petrolatum Cetearyl Alcohol Dipentaerythrityl Hexacaprylate/Hexacaprate Glyceryl Stearate Tridecyl Trimellitate PEG-100 Stearate Phenyl Trimethicone Adenosine Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Palmitoyl Tripeptide-1 Ceramide Ng Sodium Hyaluronate Magnesium Ascorbyl Phosphate Tocopherol Lecithin Linoleic Acid Linolenic Acid Retinyl Palmitate Glycyrrhiza Glabra Root Extract Camellia Oleifera Leaf Extract Citrullus Lanatus Fruit Extract Lens Esculenta Fruit Extract Pyrus Malus Fruit Extract Glycine Soja Sterols Tribehenin PEG-10 Phytosterol Magnesium Aluminum Silicate Sodium PCA Sodium Lactate Pullulan Xanthan Gum Sodium Hydroxide Neopentyl Glycol Dicaprylate/Dicaprate Cetearyl Glucoside Tridecyl Stearate Behenyl Alcohol Sclerotium Gum Carbomer C12-15 Alkyl Benzoate Sorbic Acid Phenoxyethanol Chlorphenesin Benzoic Acid Water, Ethylhexyl Stearate, Simmondsia Chinensis Seed Oil, Butylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Petrolatum, Cetearyl Alcohol, Dimethicone, Dipentaerythrityl Hexacaprylate/Hexacaprate, Glyceryl Stearate, Tridecyl Trimellitate, PEG-100 Stearate, Phenyl Trimethicone, Retinol, Adenosine, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Palmitoyl Tripeptide-1, Ceramide Ng, Sodium Hyaluronate, Magnesium Ascorbyl Phosphate, Niacinamide, Tocopherol, Lecithin, Linoleic Acid, Linolenic Acid, Retinyl Palmitate, Glycyrrhiza Glabra Root Extract, Camellia Oleifera Leaf Extract, Citrullus Lanatus Fruit Extract, Lens Esculenta Fruit Extract, Pyrus Malus Fruit Extract, Glycine Soja Sterols, Tribehenin, PEG-10 Phytosterol, Magnesium Aluminum Silicate, Sodium PCA, Sodium Lactate, Pullulan, Xanthan Gum, Sodium Hydroxide, Neopentyl Glycol Dicaprylate/Dicaprate, Cetearyl Glucoside, Tridecyl Stearate, Behenyl Alcohol, Sclerotium Gum, Carbomer, C12-15 Alkyl Benzoate, Polysorbate 20, Disodium EDTA, Sorbic Acid, Phenoxyethanol, Chlorphenesin, Benzoic Acid Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Niacinamide is a multitasking form of vitamin B3 that strengthens the skin barrier, reduces pores and dark spots, regulates oil, and improves signs of aging. And the best part? It's gentle and well-tolerated by most skin types, including sensitive and reactive skin. You might have heard of "niacin flush",