Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Clinique Smart Clinical Repair Wrinkle Correcting Cream

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Clinique Smart Clinical Repair Wrinkle Correcting Cream Detailed comparison of Olay Regenerist Retinol 24 + Peptide Night Moisturizer versus Clinique Smart Clinical Repair Wrinkle Correcting Cream.

This source-based comparison does not add ratings or recommend a winner.

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Clinique Smart Clinical Repair Wrinkle Correcting Cream Detailed comparison of Olay Regenerist Retinol 24 + Peptide Night Moisturizer versus Clinique Smart Clinical Repair Wrinkle Correcting Cream. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This anti-aging moisturizer is formulated around Acetyl Hexapeptide-8 and Acetyl Octapeptide-3 to soften the look of wrinkles and refine skin texture. Water Dimethicone Glycerin Tapioca Starch Dimethicone Crosspolymer Retinol Retinyl Propionate Niacinamide Palmitoyl Pentapeptide-4 Polyacrylamide C13-14 Isoparaffin DMDM Hydantoin Polysorbate 20 Laureth-4 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Laureth-7 Dimethiconol Polymethylsilsesquioxane Aminomethyl Propanol Titanium Dioxide Disodium EDTA Iodopropynyl Butylcarbamate Caprylic/Capric Triglyceride Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride Isostearyl Neopentanoate Butylene Glycol Glyceryl Stearate PEG-100 Stearate Cetearyl Alcohol Acetyl Hexapeptide-8 Acetyl Octapeptide-3 Aminopropyl Ascorbyl Phosphate Palmitoyl Tetrapeptide-7 Algae Extract Sodium Hyaluronate Palmitoyl Hexapeptide-12 Sigesbeckia Orientalis Extract Whey Protein Dipeptide Diaminobutyroyl Benzylamide Diacetate Acetyl Glucosamine Caffeine Palmitoyl Tripeptide-1 Glycine Soja Seed Extract Cetearyl Glucoside Tocopheryl Acetate Isohexadecane Petrolatum Caprylyl Glycol Glycereth-26 Tromethamine Glyceryl Polymethacrylate PEG-8 Hexylene Glycol Polysorbate 80 Carbomer Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Sorbitan Oleate Cetyl Alcohol Sodium Citrate Phenoxyethanol Potassium Sorbate Sodium Benzoate Water, Glycerin, Isostearyl Neopentanoate, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Cetearyl Alcohol, Acetyl Hexapeptide-8, Acetyl Octapeptide-3, Aminopropyl Ascorbyl Phosphate, Palmitoyl Tetrapeptide-7, Algae Extract, Sodium Hyaluronate, Palmitoyl Hexapeptide-12, Sigesbeckia Orientalis Extract, Whey Protein, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetyl Glucosamine, Caffeine, Palmitoyl Tripeptide-1, Glycine Soja Seed Extract, Cetearyl Glucoside, Tocopheryl Acetate, Isohexadecane, Petrolatum, Caprylyl Glycol, Glycereth-26, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Glyceryl Polymethacrylate, PEG-8, Polysorbate 20, Hexylene Glycol, Polysorbate 80, Carbomer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Sorbitan Oleate, Cetyl Alcohol, Sodium Citrate, Disodium EDTA, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all sk