Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Kiehl's Ultra Facial Cream with Squalane

Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Kiehl's Ultra Facial Cream with Squalane Detailed comparison of Olay Regenerist Retinol 24 + Peptide Night Moisturizer versus Kiehl's Ultra Facial Cream with Squalane. This anti-aging night moisturi

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Olay Regenerist Retinol 24 + Peptide Night Moisturizer Versus Kiehl's Ultra Facial Cream with Squalane Detailed comparison of Olay Regenerist Retinol 24 + Peptide Night Moisturizer versus Kiehl's Ultra Facial Cream with Squalane. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. This barrier-repair moisturizer is formulated around Squalane and Pseudoalteromonas Ferment Extract to strengthen the skin barrier and hydrate skin. Water Dimethicone Glycerin Tapioca Starch Dimethicone Crosspolymer Retinol Retinyl Propionate Niacinamide Palmitoyl Pentapeptide-4 Polyacrylamide C13-14 Isoparaffin DMDM Hydantoin Polysorbate 20 Laureth-4 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Laureth-7 Dimethiconol Polymethylsilsesquioxane Aminomethyl Propanol Titanium Dioxide Disodium EDTA Iodopropynyl Butylcarbamate Caprylic/Capric Triglyceride Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride Squalane Bis-PEG-18 Methyl Ether Dimethyl Silane Sucrose Stearate Stearyl Alcohol PEG-8 Stearate Myristyl Myristate Prunus Armeniaca Kernel Oil Phenoxyethanol Persea Gratissima Oil Glyceryl Stearate Cetyl Alcohol Oryza Sativa Bran Oil Olea Europaea Fruit Oil Chlorphenesin Stearic Acid Palmitic Acid Carbomer Trisodium Ethylenediamine Disuccinate Prunus Amygdalus Dulcis Oil Xanthan Gum Ethylhexylglycerin Sodium Hydroxide Tocopherol Glycine Soja Oil Pseudoalteromonas Ferment Extract Myristic Acid Hydroxypalmitoyl Sphinganine Salicylic Acid Helianthus Annuus Seed Oil Rosmarinus Officinalis Leaf Extract Citric Acid Water, Glycerin, Dimethicone, Squalane, Bis-PEG-18 Methyl Ether Dimethyl Silane, Sucrose Stearate, Stearyl Alcohol, PEG-8 Stearate, Myristyl Myristate, Prunus Armeniaca Kernel Oil, Phenoxyethanol, Persea Gratissima Oil, Glyceryl Stearate, Cetyl Alcohol, Oryza Sativa Bran Oil, Olea Europaea Fruit Oil, Chlorphenesin, Stearic Acid, Palmitic Acid, Carbomer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trisodium Ethylenediamine Disuccinate, Prunus Amygdalus Dulcis Oil, Xanthan Gum, Ethylhexylglycerin, Sodium Hydroxide, Tocopherol, Glycine Soja Oil, Pseudoalteromonas Ferment Extract, Myristic Acid, Hydroxypalmitoyl Sphinganine, Salicylic Acid, Helianthus Annuus Seed Oil, Rosmarinus Officinalis Leaf Extract, Citric Acid These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acrylates/C10-30 Alkyl Acrylate Crosspolymer is a synthetic polymer. It is used to thicken, emulsify, and improve the texture of products. As an emulsifier, it helps stabilize oil-in-water emulsions to give products an elegant feel when applied. It can also form a thin protective film on skin. One study found that a formula using this polymer helped slow down how quickly other ingredients (like DEET) were absorbed through skin. A 2024 study of over 1,300 patients confirmed that sensitization to this ingredient is rare. It is also non-mutagenic and has a clean track record. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Water. It's the most common cosmetic ingredient of all. You'll usually see it at the top of ingredient lists, meaning that it makes up the largest part of the product. So why is it so popular? Water most often acts as a solvent - this means that it helps dissolve other ingredients into the formulation. You'll also recognize water as that liquid we all need to stay alive. If you see this, drink a glass of water. Remember to stay hydrated!