Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Palmer's Moisture Rich Night Cream Versus DRMTLGY Peptide Night Cream

Palmer's Moisture Rich Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Palmer's Moisture Rich Night Cream versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Retinol and Palmitoyl Tripeptide-1 to sof

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Palmer's Moisture Rich Night Cream Versus DRMTLGY Peptide Night Cream Detailed comparison of Palmer's Moisture Rich Night Cream versus DRMTLGY Peptide Night Cream. This anti-aging night moisturizer is formulated around Retinol and Palmitoyl Tripeptide-1 to soften the look of wrinkles. This anti-aging night moisturizer is formulated around Palmitoyl Tripeptide-1 and Palmitoyl Tripeptide-5 to soften the look of wrinkles. Water Cetearyl Alcohol Theobroma Cacao Extract Cyclopentasiloxane Glyceryl Stearate PEG-100 Stearate Cyclohexasiloxane Diethylhexyl Sebacate Glycereth-26 Theobroma Cacao Seed Butter Glycerin Butyrospermum Parkii Butter Retinol Cocos Nucifera Oil Tocopherol Helianthus Annuus Seed Oil Aloe Barbadensis Leaf Juice Hydrolyzed Milk Protein Oenothera Biennis Flower Extract Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Phenoxyethanol Leuconostoc/Radish Root Ferment Filtrate Ceteareth-20 Sodium Polyacrylate Parfum Ethylhexylglycerin Tetrasodium EDTA Propylene Glycol Caprylic/Capric Triglyceride Steareth-20 N-Hydroxysuccinimide BHT Chrysin Benzyl Benzoate Coumarin Water, Cetearyl Alcohol, Theobroma Cacao Extract, Cyclopentasiloxane, Glyceryl Stearate, PEG-100 Stearate, Cyclohexasiloxane, Diethylhexyl Sebacate, Glycereth-26, Theobroma Cacao Seed Butter, Glycerin, Butyrospermum Parkii Butter, Retinol, Cocos Nucifera Oil, Tocopherol, Helianthus Annuus Seed Oil, Aloe Barbadensis Leaf Juice, Hydrolyzed Milk Protein, Oenothera Biennis Flower Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Phenoxyethanol, Leuconostoc/Radish Root Ferment Filtrate, Ceteareth-20, Sodium Polyacrylate, Parfum, Ethylhexylglycerin, Tetrasodium EDTA, Propylene Glycol, Caprylic/Capric Triglyceride, Steareth-20, N-Hydroxysuccinimide, BHT, Chrysin, Benzyl Benzoate, Coumarin Propanediol C12-15 Alkyl Benzoate Isopropyl Palmitate Undecane Cetyl Alcohol Dimethicone Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine Palmitoyl Tripeptide-5 Trifluoroacetyl Tripeptide-2 Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate Ceramide NP Ceramide AP Ceramide EOP Phytosphingosine Cholesterol Tridecane Allantoin Glycol Distearate Potassium Cetyl Phosphate Butylene Glycol Acrylates/C10-30 Alkyl Acrylate Crosspolymer Carbomer Polysorbate 20 Dextran Magnesium Chloride Disodium EDTA Sodium Hydroxide Sodium Lauroyl Lactylate Xanthan Gum Water, Glyceryl Stearate, Propanediol, C12-15 Alkyl Benzoate, Glycerin, Isopropyl Palmitate, Undecane, Butyrospermum Parkii Butter, Caprylic/Capric Triglyceride, Cetyl Alcohol, Dimethicone, PEG-100 Stearate, Palmitoyl Dipeptide-5 Diaminobutyroyl Hydroxythreonine, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Palmitoyl Tetrapeptide-7, Trifluoroacetyl Tripeptide-2, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Ceramide NP, Ceramide AP, Ceramide EOP, Phytosphingosine, Cholesterol, Tridecane, Allantoin, Tocopherol, Glycol Distearate, Potassium Cetyl Phosphate, Butylene Glycol, Ethylhexylglycerin, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Carbomer, Polysorbate 20, Dextran, Magnesium Chloride, Phenoxyethanol, Disodium EDTA, Sodium Hydroxide, Sodium Lauroyl Lactylate, Xanthan Gum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. This ingredient is also known as shea butter. It is a plant-derived extract from the nuts of the Africa shea tree and one of the most well-studied emollients. Because it has a high concentration of fatty acids (primarily oleic, stearic, and linoleic) it is able to form a protective barrier on the skin's surface. This helps seal in moisture and prevents transepidermal water loss (TEWL). In vitro research found an increase in skin hydration by 58% and a decrease in TEWL by 37.8% after 24 hours of applying this ingredient (pretty impressive for a single ingredient!). Besides hydration, shea butter also contains triterpenes that have anti-inflammatory potential. In particule, lupeol cinnamate has shown the highest anti-inflammatory activity in vivo. Shea butter also contains vitamins A and E which may contribute to antioxidant activity. While Shea Butter has an SPF rating of about 3-4, it is not a sunscreen replacement. This ingredient may not be fungal acne safe because its fatty acids fall within the C11-C24 range that the Malassezia yeast can metabolize. Caprylic/Capric Triglyceride (aka MCT Oil) is a lightweight emollient, solvent, and texture enhancer. It is considered a skin-softener by helping to prevent moisture loss. Though it behaves like an oil, it is not technically one due to its chemical composition. One perk of this ingredient is that it is very stable, resistant to oxidation, and unlikely to go rancid. In practice, that translates to a long shelf life and a consistently elegant skin feel. While there is an assumption Caprylic Triglyceride can clog pores due to it being derived from coconut oil, there is no research supporting this. Just patch test if you have concerns. Fractionated coconut oil and MCT Oil are both listed as Caprylic/Capric Triglyceride according to INCI. This is because INCI names are based on the ingredient’s final chemical composition and not its marketing name or source. This ingredient is treated as the gold standard fungal acne safe oil. Even though it is coconut derived, the problematic lauric acid is stripped out. This leaves just caprylic (C8) and capric (C10) acid. These chain lengths actually trend antifungal; a 2020 study found caprylic acid was enough to disrupt Malassezia furfur cell membrane, with a caprylic acid derivative damaging membrane structures at concentrations as low as 0.2%. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound natur