Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice 1% Retinol Booster Versus Clinique Smart Clinical Repair Wrinkle Correcting Serum

Paula's Choice 1% Retinol Booster Versus Clinique Smart Clinical Repair Wrinkle Correcting Serum Detailed comparison of Paula's Choice 1% Retinol Booster versus Clinique Smart Clinical Repair Wrinkle Correcting Serum. This anti-aging treatment is formulated ar

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Paula's Choice 1% Retinol Booster Versus Clinique Smart Clinical Repair Wrinkle Correcting Serum Detailed comparison of Paula's Choice 1% Retinol Booster versus Clinique Smart Clinical Repair Wrinkle Correcting Serum. This anti-aging treatment is formulated around Retinol and Ceramide NP to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Acetyl Hexapeptide-8 and Palmitoyl Tripeptide-1 to soften the look of wrinkles and refine skin texture. Water Glycerin Carthamus Tinctorius Seed Oil Polyglyceryl-10 Caprylate/Caprate Butylene Glycol Pyrus Malus Fruit Extract Polysorbate 20 Retinol Glycyrrhiza Glabra Root Ceramide NP Palmitoyl Tripeptide-1 Avena Sativa Kernel Extract Epilobium Angustifolium Extract Arctium Lappa Seed Oil Salix Alba Extract Allantoin Dipotassium Glycyrrhizate Caprylyl Glycol Polyglyceryl-10 Laurate Dipentaerythrityl Hexacaprylate/Hexacaprate Ethylhexyl Olivate Hydrogenated Lecithin Glyceryl Ascorbate Disodium EDTA Sorbic Acid Xanthan Gum Phenoxyethanol Water, Glycerin, Carthamus Tinctorius Seed Oil, Polyglyceryl-10 Caprylate/Caprate, Butylene Glycol, Pyrus Malus Fruit Extract, Polysorbate 20, Retinol, Glycyrrhiza Glabra Root, Ceramide NP, Palmitoyl Tripeptide-1, Avena Sativa Kernel Extract, Epilobium Angustifolium Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Allantoin, Dipotassium Glycyrrhizate, Caprylyl Glycol, Polyglyceryl-10 Laurate, Dipentaerythrityl Hexacaprylate/Hexacaprate, Ethylhexyl Olivate, Hydrogenated Lecithin, Glyceryl Ascorbate, Disodium EDTA, Sorbic Acid, Xanthan Gum, Phenoxyethanol Dimethicone Isododecane Polysilicone-11 Ascorbyl Glucoside Sodium Hyaluronate Tocopheryl Acetate Squalane Hypnea Musciformis Extract Gelidiella Acerosa Extract Sigesbeckia Orientalis Extract Helianthus Annuus Seed Extract Hordeum Vulgare Extract Triticum Vulgare Germ Extract Cucumis Sativus Fruit Extract Caffeine Acetyl Hexapeptide-8 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 PEG-10 Dimethicone Glycyrrhetinic Acid Whey Protein Isohexadecane Propylene Glycol Dicaprate Hydroxypinacolone Retinoate Acetyl Glucosamine Cholesterol PEG-8 Faex Extract PEG-6 Dimethyl Isosorbide Glyceryl Polymethacrylate Sodium Phosphate Synthetic Fluorphlogopite Polysorbate 80 Carbomer Hexylene Glycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Acrylamide/Sodium Acryloyldimethyltaurate Copolymer Potassium Hydroxide Tin Oxide Disodium Phosphate Citric Acid Sodium Citrate Potassium Sorbate CI 77891 Water, Dimethicone, Isododecane, Butylene Glycol, Glycerin, Polysilicone-11, Ascorbyl Glucoside, Sodium Hyaluronate, Tocopheryl Acetate, Squalane, Hypnea Musciformis Extract, Gelidiella Acerosa Extract, Sigesbeckia Orientalis Extract, Helianthus Annuus Seed Extract, Hordeum Vulgare Extract, Triticum Vulgare Germ Extract, Cucumis Sativus Fruit Extract, Caffeine, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, PEG-10 Dimethicone, Glycyrrhetinic Acid, Whey Protein, Isohexadecane, Propylene Glycol Dicaprate, Caprylyl Glycol, Hydroxypinacolone Retinoate, Acetyl Glucosamine, Cholesterol, PEG-8, Faex Extract, PEG-6, Dimethyl Isosorbide, Glyceryl Polymethacrylate, Polysorbate 20, Sodium Phosphate, Synthetic Fluorphlogopite, Polysorbate 80, Carbomer, Hexylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Acrylamide/Sodium Acryloyldimethyltaurate Copolymer, Potassium Hydroxide, Tin Oxide, Disodium Phosphate, Citric Acid, Disodium EDTA, Sodium Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibrobla