Paula's Choice 1% Retinol Booster Versus Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles

Paula's Choice 1% Retinol Booster Versus Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles Detailed comparison of Paula's Choice 1% Retinol Booster versus Vichy LiftActiv Pure Retinol Serum for Deep Wrinkles. This anti-aging treatment is formulated around Retinol and Ceramide NP to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Retinol and Palmitoyl Tetrapeptide-7 to soften the look of wrinkles and refine skin texture. Water Glycerin Carthamus Tinctorius Seed Oil Polyglyceryl-10 Caprylate/Caprate Butylene Glycol Pyrus Malus Fruit Extract Polysorbate 20 Retinol Glycyrrhiza Glabra Root Ceramide NP Palmitoyl Tripeptide-1 Avena Sativa Kernel Extract Epilobium Angustifolium Extract Arctium Lappa Seed Oil Salix Alba Extract Allantoin Dipotassium Glycyrrhizate Caprylyl Glycol Polyglyceryl-10 Laurate Dipentaerythrityl Hexacaprylate/Hexacaprate Ethylhexyl Olivate Hydrogenated Lecithin Glyceryl Ascorbate Disodium EDTA Sorbic Acid Xanthan Gum Phenoxyethanol Water, Glycerin, Carthamus Tinctorius Seed Oil, Polyglyceryl-10 Caprylate/Caprate, Butylene Glycol, Pyrus Malus Fruit Extract, Polysorbate 20, Retinol, Glycyrrhiza Glabra Root, Ceramide NP, Palmitoyl Tripeptide-1, Avena Sativa Kernel Extract, Epilobium Angustifolium Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Allantoin, Dipotassium Glycyrrhizate, Caprylyl Glycol, Polyglyceryl-10 Laurate, Dipentaerythrityl Hexacaprylate/Hexacaprate, Ethylhexyl Olivate, Hydrogenated Lecithin, Glyceryl Ascorbate, Disodium EDTA, Sorbic Acid, Xanthan Gum, Phenoxyethanol Pentylene Glycol Isononyl Isononanoate Alcohol Denat. Dicaprylyl Ether Glycine Soja Oil Propylene Glycol PEG-6 Caprylic/Capric Glycerides Hydrolyzed Rice Protein Hydroxyacetophenone Palmitoyl Tetrapeptide-7 Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate Sodium Hyaluronate Sodium Hydroxide Trisodium Ethylenediamine Disuccinate Vitreoscilla Ferment Dicaprylyl Carbonate Ammonium Polyacryloyldimethyl Taurate Carbomer Glyceryl Isostearate PPG-6-Decyltetradeceth-30 Sodium Lactate Tocopherol Water, Glycerin, Pentylene Glycol, Isononyl Isononanoate, Alcohol Denat., Dicaprylyl Ether, Glycine Soja Oil, Propylene Glycol, PEG-6 Caprylic/Capric Glycerides, Hydrolyzed Rice Protein, Hydroxyacetophenone, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Sodium Hyaluronate, Sodium Hydroxide, Trisodium Ethylenediamine Disuccinate, Vitreoscilla Ferment, Retinol, Dicaprylyl Carbonate, Ammonium Polyacryloyldimethyl Taurate, Butylene Glycol, Caprylyl Glycol, Carbomer, Glyceryl Isostearate, Polysorbate 20, PPG-6-Decyltetradeceth-30, Sodium Lactate, Tocopherol, Xanthan Gum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Palmitoyl Tripeptide-1 (aka Pal-GHK) is a synthetic signal peptide made of three amino acids attached to palmitic acid. That fatty acid attachment is the key: it boosts the peptide's ability to penetrate the skin barrier. This puts it closer to the dermal cells where it can actually make a difference. Once there, it acts as a matrikine, a signaling peptide that prompts fibroblasts to produce more collagen, fibronectin, and hyaluronic acid. In vitro studies show it can boost collagen production in skin cells even when UV-damaged skin samples were treated with it at a tiny concentration (it almost fully restored dermal collagen at 5ppm). It achieved this at 100x lower concentration than retinoic acid, which needed 500 ppm to do the same thing. Human clinical data is promising, but modest: A study of 23 female volunteers found a small but statistically significant increase (~4%) in skin thickness after treatment at 4 ppm. A separate small trial of 15 women showed statistically significant reductions in wrinkle length, depth, and skin roughness after applying it twice daily for four weeks. You'll likely see Pal-GHK paired with Palmitoyl Tetrapeptide-7 as part of the Matrixyl 3000 complex. Fungal acne note: