Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice 1% Retinol Treatment Versus Paula's Choice 1% Retinol Treatment

Paula's Choice 1% Retinol Treatment Versus Paula's Choice 1% Retinol Treatment Detailed comparison of Paula's Choice 1% Retinol Treatment EU versus Paula's Choice 1% Retinol Treatment US. This anti-aging treatment is formulated around Retinol and Tetrahexyldec

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Paula's Choice 1% Retinol Treatment Versus Paula's Choice 1% Retinol Treatment Detailed comparison of Paula's Choice 1% Retinol Treatment EU versus Paula's Choice 1% Retinol Treatment US. This anti-aging treatment is formulated around Retinol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. Water Dimethicone Glycerin Butylene Glycol Isononyl Isononanoate Castor Isostearate Succinate Glyceryl Stearate C12-15 Alkyl Benzoate Dimethicone Crosspolymer PEG-33 Polysorbate 20 Behenyl Alcohol Tetrahexyldecyl Ascorbate PEG-100 Stearate Pentaerythrityl Tetraisostearate Polymethylsilsesquioxane Retinol Ceramide Ng Palmitoyl Tripeptide-1 Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Morus Alba Root Extract Glycine Soja Sterols Lecithin Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Sorbitan Laurate Acetyl Dipeptide-1 Cetyl Ester Disodium EDTA Hydroxyethylcellulose Sodium Hydroxide Tribehenin Caprylyl Glycol Ethylhexylglycerin Pentylene Glycol PEG-75 Shea Butter Glycerides PPG-12/Smdi Copolymer PEG-10 Phytosterol PEG-8 Dimethicone PEG-14 Magnesium Aluminum Silicate Arachidyl Glucoside Sclerotium Gum Arachidyl Alcohol Benzoic Acid Carbomer Phenoxyethanol Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, Tetrahexyldecyl Ascorbate, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Retinol, Ceramide Ng, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Morus Alba Root Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethicone, PEG-14, Magnesium Aluminum Silicate, Arachidyl Glucoside, Sclerotium Gum, Arachidyl Alcohol, Benzoic Acid, Carbomer, Phenoxyethanol Sodium Hyaluronate Arctium Lappa Seed Oil Salix Alba Extract Water, Dimethicone, Glycerin, Butylene Glycol, Isononyl Isononanoate, Castor Isostearate Succinate, Glyceryl Stearate, C12-15 Alkyl Benzoate, Dimethicone Crosspolymer, PEG-33, Polysorbate 20, Behenyl Alcohol, PEG-100 Stearate, Pentaerythrityl Tetraisostearate, Polymethylsilsesquioxane, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Seed Oil, Salix Alba Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Sorbitan Laurate, Acetyl Dipeptide-1 Cetyl Ester, Disodium EDTA, Hydroxyethylcellulose, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Ethylhexylglycerin, Pentylene Glycol, PEG-75 Shea Butter Glycerides, PPG-12/Smdi Copolymer, PEG-10 Phytosterol, PEG-8 Dimethi These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Dipeptide-1 Cetyl Ester is a peptide composed of amino acids arginine and tyrosine. This peptide is considered a neurotransmitter peptide, meaning it has pain-relieving and relaxing properties. It has the ability to calm skin irritation from external factors such as chemical stinging or heat. Neurotransmitter peptides are also often called "botox in a bottle". This is because these peptides have the ability to relax the muscles. Though relaxing the muscles can prevent expression lines (as we have seen in botox), the studies do not show these peptides to be a botox replacement. The effects of this muscle relaxation is also short-term, as opposed to longer-term results from botox. Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics. Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity. Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation. It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh. Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated. This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%. Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating. Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism. Arachidyl Alcohol is a fatty alcohol made from the the arachidic acid found in peanut oil. Despite having "alcohol" in the name, it is not related to denatured alcohol or ethanol. This ingredient is a multitasker: Just be sure to patch this ingredient if you have a peanut allergy (though this ingredient is highly processed and the allergenic proteins are typically removed). This ingredient is a plant-based surfactant and emulsifier. It helps oil and water based ingredients mix evenly to improve formula stability without adding a "greasy" feel. Avena Sativa Kernel Extract is is derived from colloidal oatmeal. Besides being a healthy breakfast, oats have many benefits in skincare too. This ingredient helps sooth, hydrate, and protect the skin. The starches in colloidal oatmeal are able to bind water, keeping the skin hydrated. The cellulose and fiber in colloidal oatmeal help reduce inflammation. This can also help the skin feel softer. Colloidal Oatmeal is also an antioxidant. Antioxidants protect o