Paula's Choice 10% Azelaic Acid Booster Versus Dr. Sheth's Probiotics & Azelaic Acid Serum

Paula's Choice 10% Azelaic Acid Booster Versus Dr. Sheth's Probiotics & Azelaic Acid Serum Detailed comparison of Paula's Choice 10% Azelaic Acid Booster versus Dr. Sheth's Probiotics & Azelaic Acid Serum. This calming treatment is formulated around Azelaic Acid and Salicylic Acid to calm redness and fade the look of dark spots. This acne serum is formulated around Azelaic Acid to clear breakouts and calm redness. Water Azelaic Acid C12-15 Alkyl Benzoate Caprylic/Capric Triglyceride Methyl Glucose Sesquistearate Glycerin Cetearyl Alcohol Glyceryl Stearate Dimethicone Salicylic Acid Adenosine Glycyrrhiza Glabra Root Extract Boerhavia Diffusa Root Extract Allantoin Bisabolol Cyclopentasiloxane Xanthan Gum Sclerotium Gum Propanediol Butylene Glycol Phenoxyethanol Water, Azelaic Acid, C12-15 Alkyl Benzoate, Caprylic/Capric Triglyceride, Methyl Glucose Sesquistearate, Glycerin, Cetearyl Alcohol, Glyceryl Stearate, Dimethicone, Salicylic Acid, Adenosine, Glycyrrhiza Glabra Root Extract, Boerhavia Diffusa Root Extract, Allantoin, Bisabolol, Cyclopentasiloxane, Xanthan Gum, Sclerotium Gum, Propanediol, Butylene Glycol, Phenoxyethanol Propylene Glycol Caprylyl Methicone PEG-12 Dimethicone/PPG-20 Crosspolymer Palmaria Palmata Extract Alpha-Glucan Oligosaccharide Polymnia Sonchifolia Root Juice Maltodextrin Lactobacillus Sodium Acrylates Copolymer Lecithin Arginine Ethoxydiglycol Ammonium Acryloyldimethyltaurate/Vp Copolymer Ethylhexylglycerin Polymethylsilsesquioxane Tocopheryl Acetate Disodium EDTA Water, Azelaic Acid, Propylene Glycol, Caprylyl Methicone, PEG-12 Dimethicone/PPG-20 Crosspolymer, Cyclopentasiloxane, Palmaria Palmata Extract, Alpha-Glucan Oligosaccharide, Polymnia Sonchifolia Root Juice, Maltodextrin, Lactobacillus, Sodium Acrylates Copolymer, Lecithin, Arginine, Ethoxydiglycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Phenoxyethanol, Ethylhexylglycerin, Polymethylsilsesquioxane, Tocopheryl Acetate, Disodium EDTA Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Azelaic acid is a multitasker ingredient that helps treat acne, pigmentation, and irritation. It is a great option for sensitive skin. What makes it special? OTC Azelaic acid is usually available in concentrations from 10-15% and anything over requires a prescription. Here's what each tier does best: Unlike other acids, azelaic acid will not make your skin more photosensitive/sun sensitive. Though this ingredient is naturally occurring in grains like wheat, rye, and barley, it is usually synthetically created for cosmetics to ensure stability and effectiveness. Cyclopentasiloxane (D5) is a lightweight silicone that mostly acts as an emollient and solvent in cosmetics. Its the reason your products feel silky, fast-spreading, and non-greasy. Since D5 is volatile, it does its thing and then evaporates off the skin quickly. The safety profile of this ingredient is reassuring; the US CIR Expert Panel concluded D5 is safe as used in cosmetics and Health Canada concluded that D5 is not harmful to human health or the environment as currently used in cosmetics There's a study that people mention about D5 in a rat study showing tumors. This study is related to long-term inhalation of high D5 levels. Regulatory bodies have judged this study to be not applicable in topical skincare since skin absorption of D5 is very low and we're not really inhaling huge amounts of D5. The only restriction for this ingredient is environmental. The European Chemicals Agency (ECHA) restricted D5 in wash-off cosmetics at or above 0.1% due to their persistence in water. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures roughly 200x higher than what people get from cosmetics. And despite its very widespread use, this ingred