Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice 10% Niacinamide Booster Versus Paula's Choice Clinical Niacinamide 20% Treatment

Paula's Choice 10% Niacinamide Booster Versus Paula's Choice Clinical Niacinamide 20% Treatment Detailed comparison of Paula's Choice 10% Niacinamide Booster versus Paula's Choice Clinical Niacinamide 20% Treatment. This pore-care treatment is formulated aroun

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Paula's Choice 10% Niacinamide Booster Versus Paula's Choice Clinical Niacinamide 20% Treatment Detailed comparison of Paula's Choice 10% Niacinamide Booster versus Paula's Choice Clinical Niacinamide 20% Treatment. This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture. Water Niacinamide Acetyl Glucosamine Ascorbyl Glucoside Butylene Glycol Phospholipids Sodium Hyaluronate Allantoin Boerhavia Diffusa Root Extract Glycerin Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Ubiquinone Epigallocatechin Gallate Beta-Glucan Panthenol Carnosine Genistein Citric Acid Sodium Citrate Sodium Hydroxide Xanthan Gum Disodium EDTA Ethylhexylglycerin Phenoxyethanol Water, Niacinamide, Acetyl Glucosamine, Ascorbyl Glucoside, Butylene Glycol, Phospholipids, Sodium Hyaluronate, Allantoin, Boerhavia Diffusa Root Extract, Glycerin, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Ubiquinone, Epigallocatechin Gallate, Beta-Glucan, Panthenol, Carnosine, Genistein, Citric Acid, Sodium Citrate, Sodium Hydroxide, Xanthan Gum, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol Niacinamide 20% Pentylene Glycol Spiraea Ulmaria Extract Portulaca Oleracea Extract Camellia Japonica Flower Extract Camellia Sinensis Leaf Extract Lecithin Pullulan Silica Sclerotium Gum Propanediol Sodium Phytate Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Acetyl Glucosamine is an antioxidant and humectant. It is an amino acid sugar and is naturally found in our skin. The cool thing about this ingredient? It helps the skin produce hyaluronic acid and boost hydration. It also has antioxidant benefits to protect skin cells. When paired with niacinamide, Acetyl Glucosamine has been shown to be effective at reducing discoloration. Allantoin is a soothing ingredient known for its protective and moisturizing properties; it's basically a quiet workhorse ingredient you can find in a huge range of cosmetics. Though it can be derived from the comfrey plant, allantoin is produced synthetically for cosmetic products to ensure purity. Research shows it can encourage your skin cells to turn over and renew by stimulating keratinocyte and fibroblast proliferation. It also has mild keratolytic properties to help loosen and shed dead skin cells without being harsh. Studies also suggest allantoin can help calm inflammation by dialing down some of the chemical signals your skin sends out when it is irritated. This ingredient is typically used in the 0.1-0.5% range, and the FDA recognizes it as a skin protectant in OTC products up to 2%. Overall, allantoin is a wonderful addition to most routines; it is stable across a wide pH range (~4-8), works well with other ingredients, and is considered non-sensitizing/non-irritating. Fun fact: Allantoin is naturally occurring in comfrey root, beets, chamomile, and wheat sprouts. Our bodies even produce it as a byproduct of uric acid metabolism. Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there. It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize. Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause. The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate. These studies also showed AA-2G released vitamin C over a longer period. A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days. And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo. There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too. Typical usage is usually between 0.5-5% and most studies/products land around 2%. AA-2G perfo