Paula's Choice Barrier Repair Advanced Moisturizer Versus La Roche-Posay Toleriane Double Repair Face Moisturizer

Paula's Choice Barrier Repair Advanced Moisturizer Versus La Roche-Posay Toleriane Double Repair Face Moisturizer Detailed comparison of Paula's Choice Barrier Repair Advanced Moisturizer US versus La Roche-Posay Toleriane Double Repair Face Moisturizer. This barrier-repair moisturizer is formulated around Squalane and Ceramide NP to strengthen the skin barrier and hydrate skin. This barrier-repair moisturizer is formulated around Squalane and Niacinamide to strengthen the skin barrier and hydrate skin. Water Dicaprylyl Carbonate Ethylhexyl Stearate Glycerin Cocoglycerides Squalane Sodium Polyacrylate Butyrospermum Parkii Butter Ceramide NP Ceramide AP Ceramide As Ceramide Ns Ceramide EOP Sodium Hyaluronate Adenosine Palmitoyl Tripeptide-5 Citrullus Lanatus Seed Oil Glyceryl Stearate Caprylyl Glycol Hydroxyacetophenone Sodium Stearoyl Glutamate Hexylene Glycol Tocopherol 2,3-Butanediol Xanthan Gum Ethylhexylglycerin Sodium Phytate Sodium PCA Urea Hydrogenated Lecithin Trehalose Polyquaternium-51 Triacetin Cholesterol Phenoxyethanol Water, Dicaprylyl Carbonate, Ethylhexyl Stearate, Glycerin, Cocoglycerides, Squalane, Sodium Polyacrylate, Butyrospermum Parkii Butter, Ceramide NP, Ceramide AP, Ceramide As, Ceramide Ns, Ceramide EOP, Sodium Hyaluronate, Adenosine, Palmitoyl Tripeptide-5, Citrullus Lanatus Seed Oil, Glyceryl Stearate, Caprylyl Glycol, Hydroxyacetophenone, Sodium Stearoyl Glutamate, Hexylene Glycol, Tocopherol, 2,3-Butanediol, Xanthan Gum, Ethylhexylglycerin, Sodium Phytate, Sodium PCA, Urea, Hydrogenated Lecithin, Trehalose, Polyquaternium-51, Triacetin, Cholesterol, Phenoxyethanol Dimethicone Zea Mays Starch Niacinamide Ammonium Polyacryloyldimethyl Taurate Myristyl Myristate Stearic Acid Potassium Cetyl Phosphate Glyceryl Stearate Se Sodium Hydroxide Myristic Acid Palmitic Acid Capryloyl Glycine Water, Glycerin, Squalane, Dimethicone, Zea Mays Starch, Niacinamide, Ammonium Polyacryloyldimethyl Taurate, Myristyl Myristate, Stearic Acid, Ceramide NP, Potassium Cetyl Phosphate, Glyceryl Stearate Se, Sodium Hydroxide, Myristic Acid, Palmitic Acid, Capryloyl Glycine, Caprylyl Glycol, Xanthan Gum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Ceramide NP (formerly known as Ceramide 3) is one of the skin's naturally occurring lipids. Since ceramides are the major lipid components of the skin, they are crucial for maintaining skin barrier and hydration. Ceramide NP most closely mirrors the dominant kind in human skin amongst ceramide subtypes. This ceramide works by slotting into gaps within the stratum corneum's lipid matrix to limit trans-epidermal water loss (TEWL) and shield the skin against external irritants. A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%. Another clinical study in subjects aged 60 and older found that a ceramide body wash and moisturizer improved skin dryness and itchy skin in 15 days. Overall, ceramides are considered non-irritating and safety tests have found little to no observable adverse effects from using this ingredient. Ceramide NP is usually sourced from plants (like soybean or rice bran), or produced synthetically. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Squalane is the hydrogenated and shelf-stable form of squalene (a lipid that naturally occurs in human sebum). It is an emollient and skin conditioning agent that is able to integrate seamlessly into the skin's lipid barrier without clogging pores. This is due to how structurally similar it is to what your skin already produces. Though it is mostly an emollient that helps soften and hydrate skin, it also has some humectant and occlusive action. Humectants help the skin retain moisture while occlusives seal it in, making squalane a triple-threat moisturizer. Res