Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus La Roche-Posay Retinol B3 Serum

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus La Roche-Posay Retinol B3 Serum Detailed comparison of Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment versus La Roche-Posay Retinol B3 Serum. This anti-aging treatment is formu

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Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus La Roche-Posay Retinol B3 Serum Detailed comparison of Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment versus La Roche-Posay Retinol B3 Serum. This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. This anti-aging serum is formulated around Niacinamide and Retinol to soften the look of wrinkles and fade the look of dark spots. Water Dimethicone Pentaerythrityl Tetraisostearate Isononyl Isononanoate Butylene Glycol Bakuchiol Arachidyl Alcohol Glyceryl Polymethacrylate Dimethicone Crosspolymer Behenyl Alcohol Glycerin PEG-75 Shea Butter Glycerides Glyceryl Stearate C12-15 Alkyl Benzoate Polysorbate 20 Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Sodium Hyaluronate Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Salix Alba Bark Extract Glycine Soja Sterols Lecithin Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Palmitoyl Tripeptide-1 Sodium Hydroxide Tribehenin Caprylyl Glycol Dipeptide-2 Polygonum Cuspidatum Root Extract PEG-10 Phytosterol PEG-8 Magnesium Aluminum Silicate Arachidyl Glucoside Chrysin Pentylene Glycol Sodium Acrylates Copolymer Steareth-20 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol Coco-Glucoside Hesperidin Methyl Chalcone N-Hydroxysuccinimide Disodium EDTA Phenoxyethanol Benzoic Acid Ethylhexylglycerin Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin Cyclohexasiloxane Alcohol Denat. Niacinamide Glycine Soja Oil PPG-6-Decyltetradeceth-30 Adenosine Ammonium Polyacryloyldimethyl Taurate Citric Acid Trisodium Ethylenediamine Disuccinate Xanthan Gum Polysilicone-11 Retinyl Palmitate Tocopherol Parfum Water, Glycerin, Cyclohexasiloxane, Alcohol Denat., Pentylene Glycol, Niacinamide, Dimethicone, Glycine Soja Oil, PPG-6-Decyltetradeceth-30, Sodium Hyaluronate, Retinol, Adenosine, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Citric Acid, Trisodium Ethylenediamine Disuccinate, Xanthan Gum, Polysilicone-11, Retinyl Palmitate, Tocopherol, Phenoxyethanol, Parfum These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Caprylyl Glycol is a humectant, skin conditioner, emollient, and preservative booster derived from either caprylic acid or synthetically created. Typical use levels vary from 0.3-1% as a preservative booster and go up to 2% to condition skin. Because it is not a free-fatty acid, this ingredient is fungal acne safe (there's nothing for Malassezia to feed on). Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula: Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses. On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations. Typical use levels in a formula run about 1-5%. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural