Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer

Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment versus Olay Regenerist Retinol 24 + Peptide Night M

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Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment Versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer Detailed comparison of Paula's Choice Clinical 0.3% Retinol + 2% Bakuchiol Treatment versus Olay Regenerist Retinol 24 + Peptide Night Moisturizer. This anti-aging treatment is formulated around Bakuchiol and Tetrahexyldecyl Ascorbate to soften the look of wrinkles and refine skin texture. This anti-aging night moisturizer is formulated around Retinol and Niacinamide to soften the look of wrinkles and refine skin texture. Water Dimethicone Pentaerythrityl Tetraisostearate Isononyl Isononanoate Butylene Glycol Bakuchiol Arachidyl Alcohol Glyceryl Polymethacrylate Dimethicone Crosspolymer Behenyl Alcohol Glycerin PEG-75 Shea Butter Glycerides Glyceryl Stearate C12-15 Alkyl Benzoate Polysorbate 20 Tetrahexyldecyl Ascorbate Retinol Ceramide Ng Palmitoyl Tetrapeptide-7 Palmitoyl Hexapeptide-12 Sodium Hyaluronate Dipotassium Glycyrrhizate Glycyrrhiza Glabra Root Extract Avena Sativa Kernel Extract Arctium Lappa Root Extract Salix Alba Bark Extract Glycine Soja Sterols Lecithin Allantoin Tocopheryl Acetate Hydrolyzed Soy Protein Palmitoyl Tripeptide-1 Sodium Hydroxide Tribehenin Caprylyl Glycol Dipeptide-2 Polygonum Cuspidatum Root Extract PEG-10 Phytosterol PEG-8 Magnesium Aluminum Silicate Arachidyl Glucoside Chrysin Pentylene Glycol Sodium Acrylates Copolymer Steareth-20 Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer Cetearyl Alcohol Coco-Glucoside Hesperidin Methyl Chalcone N-Hydroxysuccinimide Disodium EDTA Phenoxyethanol Benzoic Acid Ethylhexylglycerin Water, Dimethicone, Pentaerythrityl Tetraisostearate, Isononyl Isononanoate, Butylene Glycol, Bakuchiol, Arachidyl Alcohol, Glyceryl Polymethacrylate, Dimethicone Crosspolymer, Behenyl Alcohol, Glycerin, PEG-75 Shea Butter Glycerides, Glyceryl Stearate, C12-15 Alkyl Benzoate, Polysorbate 20, Tetrahexyldecyl Ascorbate, Retinol, Ceramide Ng, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Sodium Hyaluronate, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract, Avena Sativa Kernel Extract, Arctium Lappa Root Extract, Salix Alba Bark Extract, Glycine Soja Sterols, Lecithin, Allantoin, Tocopheryl Acetate, Hydrolyzed Soy Protein, Palmitoyl Tripeptide-1, Sodium Hydroxide, Tribehenin, Caprylyl Glycol, Dipeptide-2, Polygonum Cuspidatum Root Extract, PEG-10 Phytosterol, PEG-8, Magnesium Aluminum Silicate, Arachidyl Glucoside, Chrysin, Pentylene Glycol, Sodium Acrylates Copolymer, Steareth-20, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Alcohol, Coco-Glucoside, Hesperidin Methyl Chalcone, N-Hydroxysuccinimide, Disodium EDTA, Phenoxyethanol, Benzoic Acid, Ethylhexylglycerin Tapioca Starch Retinyl Propionate Niacinamide Palmitoyl Pentapeptide-4 Polyacrylamide C13-14 Isoparaffin DMDM Hydantoin Laureth-4 Acrylates/C10-30 Alkyl Acrylate Crosspolymer Laureth-7 Dimethiconol Polymethylsilsesquioxane Aminomethyl Propanol Titanium Dioxide Iodopropynyl Butylcarbamate Caprylic/Capric Triglyceride Water, Dimethicone, Glycerin, Tapioca Starch, Dimethicone Crosspolymer, Retinol, Retinyl Propionate, Niacinamide, Palmitoyl Pentapeptide-4, Polyacrylamide, C13-14 Isoparaffin, DMDM Hydantoin, Polysorbate 20, Laureth-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Laureth-7, Dimethiconol, Polymethylsilsesquioxane, Aminomethyl Propanol, Titanium Dioxide, Disodium EDTA, Iodopropynyl Butylcarbamate, Caprylic/Capric Triglyceride These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Dimethicone is a type of synthetic silicone created from natural materials such as quartz. It is also known as polydimethylsiloxane. What it does: Dimethicone comes in different viscosities: Depending on the viscosity, dimethicone has different properties. Ingredients lists don't always show which type is used, so we recommend reaching out to the brand if you have questions about the viscosity. This ingredient is unlikely to cause irritation because it does not get absorbed into skin. However, people with silicone allergies should be careful about using this ingredient. Note: Dimethicone may contribute to pilling. This is because it is not oil or water soluble, so pilling may occur when layered with products. When mixed with heavy oils in a formula, the outcome is also quite greasy. Dimethicone Crosspolymer is a silicone created by modifying dimethicone with hydrocarbon side chains. Due to its large size, it does not penetrate skin. It is considered non-occlusive. Dimethicone Crosspolymer is used to stabilize and thicken products. It also helps give products a silky feel. Disodium EDTA is a chelating agent. It grabs onto and deactivates metal ions that sneak into your products from water, packaging, or air. This ingredient mainly works behind the scenes and helps with: On top of that, this ingredient can counteract the effects of hard water by binding to the minerals in it. One thing worth knowing is that Disodium EDTA has been shown to be a mild penetration enhancer. It can help other ingredients absorb into skin more effectively which can be a double-edged sword (great for actives, but can also make the active too strong if you have sensitive skin). Clinical patch testing showed no significant skin irritation at typical use concentrations and minimal dermal absorption. You'll most likely see this ingredient near the end of an ingredient list. It's typically found in concentrations less than 1%. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Polysorbate