Paula's Choice Clinical Niacinamide 20% Treatment Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

Paula's Choice Clinical Niacinamide 20% Treatment Versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum Detailed comparison of Paula's Choice Clinical Niacinamide 20% Treatment versus Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum. This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture. This barrier-repair serum is formulated around Bifida Ferment Lysate and Sodium Hyaluronate to strengthen the skin barrier and soften the look of wrinkles. No concerns Water Niacinamide 20% Pentylene Glycol Butylene Glycol Glycerin Acetyl Glucosamine Ascorbyl Glucoside Glycyrrhiza Glabra Root Extract Spiraea Ulmaria Extract Portulaca Oleracea Extract Camellia Japonica Flower Extract Epigallocatechin Gallate Boerhavia Diffusa Root Extract Camellia Sinensis Leaf Extract Allantoin Lecithin Pullulan Panthenol Silica Xanthan Gum Sclerotium Gum Propanediol Sodium Phytate Phenoxyethanol Ethylhexylglycerin Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin Bifida Ferment Lysate PEG-8 Bis-PEG-18 Methyl Ether Dimethyl Silane Methyl Gluceth-20 Glycereth-26 PEG-75 Adansonia Digitata Seed Extract Tripeptide-32 Sodium Hyaluronate Faex Extract Lactobacillus Ferment Cola Acuminata Seed Extract Anthemis Nobilis Flower Extract Hydrolyzed Algin Pantethine Caffeine Sodium Rna Bisabolol Squalane Oleth-3 Phosphate Caprylyl Glycol Oleth-3 Oleth-5 Choleth-24 Hydrogenated Lecithin Jojoba Wax PEG-120 Esters Ceteth-24 Tocopheryl Acetate Carbomer Triethanolamine Tetrasodium EDTA BHT Potassium Sorbate Disodium EDTA CI 14700 CI 19140 Water, Bifida Ferment Lysate, PEG-8, Propanediol, Bis-PEG-18 Methyl Ether Dimethyl Silane, Methyl Gluceth-20, Glycereth-26, PEG-75, Butylene Glycol, Adansonia Digitata Seed Extract, Tripeptide-32, Sodium Hyaluronate, Faex Extract, Lactobacillus Ferment, Cola Acuminata Seed Extract, Anthemis Nobilis Flower Extract, Hydrolyzed Algin, Pantethine, Caffeine, Lecithin, Sodium Rna, Bisabolol, Squalane, Glycerin, Oleth-3 Phosphate, Caprylyl Glycol, Oleth-3, Oleth-5, Choleth-24, Hydrogenated Lecithin, Jojoba Wax PEG-120 Esters, Ceteth-24, Tocopheryl Acetate, Carbomer, Triethanolamine, Tetrasodium EDTA, BHT, Xanthan Gum, Potassium Sorbate, Disodium EDTA, Phenoxyethanol, CI 14700, CI 19140 These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Lecithin is a term for a group of substances found in the cell membranes of plants, animals, and humans. They are made up of phospholipids. Thanks to its amphiphilic structure (water-loving head and oil-loving tail), it is a true multitasker: It plays well with most ingredients and is typically used at 0.1-1%. However, concentrations up to 50% have been reported in moisturizers. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of this ingredient is that it stays functional across a wide pH range (3-10). You'll often see it paired with boosters like Ethylhexylglycerin; one study showed that a 1:9 ratio of Ethylhexylglycerin to Phenoxyethanol damages bacterial membranes as effectively as doubling the Phenoxyethanol concentration on its own. Typical use concentrations range from 0.3-1% depending on the formula, and this ingredient is capped at 1% int the EU. Safety-wise, the fear mongering does not hold up to the evidence. The EU's Scientific Committee on Consumer Safety and FDA consider it safe as a preservative at up to 1%, including for children of all ages. Adverse systemic effects only showed up in animal studies at exposures ro