Paula's Choice Clinical Niacinamide 20% Treatment Versus RNW DER. CONCENTRATE Niacinamide Plus Serum

Paula's Choice Clinical Niacinamide 20% Treatment Versus RNW DER. CONCENTRATE Niacinamide Plus Serum Detailed comparison of Paula's Choice Clinical Niacinamide 20% Treatment versus RNW DER. CONCENTRATE Niacinamide Plus Serum. This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture. This brightening serum is formulated around Niacinamide and Glutathione to brighten dull-looking skin and fade the look of dark spots. No concerns Water Niacinamide 20% Pentylene Glycol Butylene Glycol Glycerin Acetyl Glucosamine Ascorbyl Glucoside Glycyrrhiza Glabra Root Extract Spiraea Ulmaria Extract Portulaca Oleracea Extract Camellia Japonica Flower Extract Epigallocatechin Gallate Boerhavia Diffusa Root Extract Camellia Sinensis Leaf Extract Allantoin Lecithin Pullulan Panthenol Silica Xanthan Gum Sclerotium Gum Propanediol Sodium Phytate Phenoxyethanol Ethylhexylglycerin Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin Methylpropanediol Niacinamide Alcohol Dipropylene Glycol 1,2-Hexanediol Glutathione Tranexamic Acid Nonapeptide-1 Eclipta Prostrata Leaf Extract Algae Extract Hydrogenated Lecithin Carbomer Adenosine Fructooligosaccharides Beta-Glucan Tromethamine Hydrolyzed Hyaluronic Acid Acetyl Hexapeptide-8 Copper Tripeptide-1 Palmitoyl Tetrapeptide-7 Tripeptide-1 Palmitoyl Pentapeptide-4 Palmitoyl Tripeptide-1 Hexapeptide-9 Caprylyl Glycol Water, Methylpropanediol, Glycerin, Niacinamide, Alcohol, Dipropylene Glycol, 1,2-Hexanediol, Ascorbyl Glucoside, Glutathione, Tranexamic Acid, Nonapeptide-1, Eclipta Prostrata Leaf Extract, Algae Extract, Hydrogenated Lecithin, Xanthan Gum, Carbomer, Adenosine, Fructooligosaccharides, Beta-Glucan, Butylene Glycol, Tromethamine, Hydrolyzed Hyaluronic Acid, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tetrapeptide-7, Tripeptide-1, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Hexapeptide-9, Ethylhexylglycerin, Caprylyl Glycol Be the first to review These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ascorbyl Glucoside (AA-2G) is one of the most stable vitamin C derivatives out there. It's made by attaching a glucose molecule to ascorbic acid; this glucose "cap" shields the vitamin C from air, light, heat, and metal ions that normally cause pure ascorbic acid to oxidize. Once on your skin, the enzyme alpha-glucosidase snips off the glucose and gradually releases active ascorbic acid right where it's needed. Basically, it behaves like a slow-release pro-vitamin C with less of a stinging that high-strength ascorbic acid can cause. The research supports the classic vitamin C benefits as well. In lab and human studies, AA-2G slowed down the skin's production of melanin (the pigment behind dark spots) and helped shield skin cells against sun damage better than ascorbyl phosphate. These studies also showed AA-2G released vitamin C over a longer period. A frequently cited manufacturer trial found that a 2% AA-2G face cream significantly improved wrinkle depth and skin roughness after 45 days. And in 2009, a clinical trial showed it meaningfully lightened dark patches on the gums compared to a placebo. There's also collagen-synthesis support (since vitamin C is a required cofactor for that) and an antioxidant effect too. Typical usage is usually between 0.5-5% and most studies/products land around 2%. AA-2G performs best when formulated at a mildly acidic pH (~5-7) which is much gentler than the pH that pure vitamin C demands (~2.5-3.5). Just one thing worth knowing: the in-skin conversation rate is only about 55-60% by weight. So a 5% AA-2G product delivers roughly 2.75-3% of actual active vitamin C. On top of that, skin absorption is relatively low because the ingredient is water-soluble. Butylene Glycol (or BG) is used within cosmetic products for a few different reasons: Overall, Butylene Glycol is a safe and well-rounded ingredient that works well with other ingredients. Though this ingredient works well with most skin types, some people with sensitive skin may experience a reaction such as allergic rashes, closed comedones, or itchiness. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aqu