Peptide Skincare & BeautySkin science and ingredient guides

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Paula's Choice Clinical Niacinamide 20% Treatment Versus The Ordinary Hyaluronic Acid 2% + B5

Paula's Choice Clinical Niacinamide 20% Treatment Versus The Ordinary Hyaluronic Acid 2% + B5 Detailed comparison of Paula's Choice Clinical Niacinamide 20% Treatment versus The Ordinary Hyaluronic Acid 2% + B5. This pore-care treatment is formulated around Ni

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Paula's Choice Clinical Niacinamide 20% Treatment Versus The Ordinary Hyaluronic Acid 2% + B5 Detailed comparison of Paula's Choice Clinical Niacinamide 20% Treatment versus The Ordinary Hyaluronic Acid 2% + B5. This pore-care treatment is formulated around Niacinamide and Acetyl Glucosamine to refine the look of pores and refine skin texture. This hydrating treatment is formulated around Sodium Hyaluronate and Sodium Hyaluronate Crosspolymer to hydrate skin and strengthen the skin barrier. Water Niacinamide 20% Pentylene Glycol Butylene Glycol Glycerin Acetyl Glucosamine Ascorbyl Glucoside Glycyrrhiza Glabra Root Extract Spiraea Ulmaria Extract Portulaca Oleracea Extract Camellia Japonica Flower Extract Epigallocatechin Gallate Boerhavia Diffusa Root Extract Camellia Sinensis Leaf Extract Allantoin Lecithin Pullulan Panthenol Silica Xanthan Gum Sclerotium Gum Propanediol Sodium Phytate Phenoxyethanol Ethylhexylglycerin Water, Niacinamide 20%, Pentylene Glycol, Butylene Glycol, Glycerin, Acetyl Glucosamine, Ascorbyl Glucoside, Glycyrrhiza Glabra Root Extract, Spiraea Ulmaria Extract, Portulaca Oleracea Extract, Camellia Japonica Flower Extract, Epigallocatechin Gallate, Boerhavia Diffusa Root Extract, Camellia Sinensis Leaf Extract, Allantoin, Lecithin, Pullulan, Panthenol, Silica, Xanthan Gum, Sclerotium Gum, Propanediol, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin Sodium Hyaluronate Sodium Hyaluronate Crosspolymer Ahnfeltia Concinna Extract Trisodium Ethylenediamine Disuccinate Citric Acid Isoceteth-20 Ethoxydiglycol Hexylene Glycol 1,2-Hexanediol Caprylyl Glycol Water, Sodium Hyaluronate, Pentylene Glycol, Propanediol, Sodium Hyaluronate Crosspolymer, Panthenol, Ahnfeltia Concinna Extract, Glycerin, Trisodium Ethylenediamine Disuccinate, Citric Acid, Isoceteth-20, Ethoxydiglycol, Ethylhexylglycerin, Hexylene Glycol, 1,2-Hexanediol, Phenoxyethanol, Caprylyl Glycol These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Ethylhexylglycerin is created from glycerin. It is a multitasker ingredient that: The CIR Expert Panel found minimal skin absorption or sensitization of any kind in a safety assessment. Though this ingredient is considered well-tolerated, a small number of cases of allergic dermatitis have been published since 2002. Just be sure to patch test if you are unsure. Industry-reported use ranges from 8% in rinse-off products and 2% in leave-on formulations. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Panthenol is a common ingredient that helps hydrate and soothe the skin. It is found naturally in our skin and hair. There are two forms of panthenol: D and L. D-panthenol is also known as dexpanthenol. Most cosmetics use dexpanthenol or a mixture of D and L-panthenol. Panthenol is famous due to its ability to go deeper into the skin's layers. Using this ingredient has numerous pros (and no cons): Like hyaluronic acid, panthenol is a humectant. Humectants are able to bind and hold large amounts of water to keep skin hydrated. This ingredient works well for wound healing. It works by increasing tissue in the wound and helps close open wounds. Once oxidized, panthenol converts to pantothenic acid. Panthothenic acid is found in all living cells. This ingredient is also referred to as pro-vitamin B5. Pentylene Glycol (1,2-pentanediol) is a multitasking little diol with three main roles in a formula: Research on alkanediols (the family pentylene glycol belongs to) show they work by disrupting microbial cell membranes. This disruption helps the primary preservative system in a product work more effectively at lower doses. On the safety side, the Cosmetic Ingredient Review Expert Panel has concluded this ingredient to be safe as used in current cosmetic practices + concentrations. Typical use levels in a formula run about 1-5%. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activi