Peptide Skincare & BeautySkin science and ingredient guides

Ingredient or product comparison

Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer

Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer Detailed comparison of Paula's Choice Pro-Collagen Peptide Plumping Moisturizer versus Paula's Choice Barrier Repair Advanced Moisturizer EU. Thi

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Paula's Choice Pro-Collagen Peptide Plumping Moisturizer Versus Paula's Choice Barrier Repair Advanced Moisturizer Detailed comparison of Paula's Choice Pro-Collagen Peptide Plumping Moisturizer versus Paula's Choice Barrier Repair Advanced Moisturizer EU. This anti-aging moisturizer is formulated around Squalane to soften the look of wrinkles and hydrate skin. This barrier-repair moisturizer is formulated around Ceramide Ag and Ceramide NP to strengthen the skin barrier and hydrate skin. No concerns Water Dimethicone Squalane Glycerin Pyrus Malus Fruit Extract Pentylene Glycol 1,2-Hexanediol Ammonium Acryloyldimethyltaurate/Vp Copolymer Butylene Glycol Hydroxyacetophenone Sodium Acrylates Copolymer Acrylates/C10-30 Alkyl Acrylate Crosspolymer Gigartina Stellata Extract Acetyl Sh-Hexapeptide-5 Amide Acetate Tridecapeptide-1 Oligopeptide-1 Sodium Phytate Propanediol Lecithin Hydroxypropyltrimonium Hyaluronate Cyanocobalamin Phenoxyethanol Water, Dimethicone, Squalane, Glycerin, Pyrus Malus Fruit Extract, Pentylene Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Butylene Glycol, Hydroxyacetophenone, Sodium Acrylates Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Gigartina Stellata Extract, Acetyl Sh-Hexapeptide-5 Amide Acetate, Tridecapeptide-1, Oligopeptide-1, Sodium Phytate, Propanediol, Lecithin, Hydroxypropyltrimonium Hyaluronate, Cyanocobalamin, Phenoxyethanol 2,3-Butanediol Dicaprylyl Carbonate Glyceryl Stearate Cocoglycerides Ceramide Ag Ceramide NP Sodium Hyaluronate Ceramide EOP Ceramide Ng Ceramide AP Adenosine Tocopherol Butyrospermum Parkii Butter Palmitoyl Tripeptide-5 Hexylene Glycol Trehalose Cholesterol Urea Hydrogenated Lecithin Citrullus Lanatus Seed Oil Caprylyl Glycol Sodium PCA Polyquaternium-51 Triacetin Sodium Polyacrylate Xanthan Gum Ethylhexyl Stearate Sodium Stearoyl Glutamate Ethylhexylglycerin Water, 2,3-Butanediol, Dicaprylyl Carbonate, Glycerin, Glyceryl Stearate, Cocoglycerides, Ceramide Ag, Ceramide NP, Hydroxyacetophenone, Sodium Hyaluronate, Ceramide EOP, Ceramide Ng, Ceramide AP, Adenosine, Tocopherol, Butyrospermum Parkii Butter, Palmitoyl Tripeptide-5, Hexylene Glycol, Trehalose, Cholesterol, Squalane, Sodium Phytate, Urea, Hydrogenated Lecithin, Citrullus Lanatus Seed Oil, Caprylyl Glycol, Sodium PCA, Polyquaternium-51, Triacetin, Sodium Polyacrylate, Xanthan Gum, Ethylhexyl Stearate, Phenoxyethanol, Sodium Stearoyl Glutamate, Ethylhexylglycerin These ingredients are found in both products. Ingredients higher up in an ingredient list are typically present in a larger amount. Glycerin (or glycerol) is a compound naturally found in your skin. It's a powerhouse humectant that pulls water into the stratum corneum. Topically, glycerin does several things at once: Your skin makes glycerin on its own (mostly from sebaceous oil breakdown) and shuttles it to your outermost layer of skin, or your epidermis, via aquaporin-3. Aquaporin-3 is a transporter that is essential for normal skin hydration, elasticity, and repair. Interestingly, mice lacking in AQP3 have dry and less elastic skin that can be fully corrected with glycerin. This ingredient is non-irritating, plays well with almost every ingredient, and works across all skin types. Typical use is anywhere between 3-10% but can go up to 79% in some leave-on products. Just know very high concentrations (>40%) can feel tacky in low humidity. Glycerin is the name for this ingredient in American English. British English uses Glycerol/Glycerine. Hydroxyacetophenone is a small phenolic molecule that earns its place in a formulas as an antioxidant and preservative booster. As a phenol, it is able to neutralize free radicals to protect both the product and the skin from oxidative stress. Though it can't kill microbes on its own, it works as a good supporting agent when combined with other preservatives like Phenoxyethanol or 1,2-Hexanediol. This ingredient naturally occurs as piceol in Norwegian spruce needles (~0.4-1.1% dry weight and in cloudberries). Though the cosmetic-grade material is synthesized for purity and consistency. You'll usually see it used at low levels and suppliers recommend up to 1% added to a water phase. Safety testing was done at concentrations like 0.05% in SPF products and 0.5% in a Human Repeated Insult Patch Test. The safety evidence is assuring; this ingredient is safe for cosmetics in current use and also holds safety status as a food flavoring as well. An honest caveat: the "soothing" and "anti-inflammatory" claims come mostly from supplier marketing rather than published clinical trials. The Cosmetic Ingredient Review's own literature search found no useful efficacy studies on this ingredient. So the antioxidant and preservative-boosting roles are the well supported ones while the calming benefit is plausible but thinly evidenced. Overall, this is a well-tolerated, low-irritation multitasker that quietly helps a formula stay fresh and stable. Phenoxyethanol is one of the most widely used preservatives in skincare (and for good reason!). It has a large spectrum of antimicrobial activity and especially effective bacteria, yeast, and mold while only having a weak effect on your skin's natural microbiome. On a cellular level, it disrupts the cell membranes of microbes by poking holes that make the cell leak. This shuts down the chemical reactions the microbe needs to make energy so it can no longer survive. Another perk of thi